1.
Braz J Med Biol Res
; 19(1): 27-32, 1986.
Artigo
em Inglês
| MEDLINE
| ID: mdl-3026533
RESUMO
The adenyl cyclase deficient cr-1 mutant of Neurospora crassa grew poorly in bovine serum albumin as an alternative and only source of either sulfur, nitrogen or carbon. The low growth of the cr-1 mutant in protein was correlated with limited secretion of extracellular alkaline protease. The defect was specific for the cr-1 mutant and was suppressed by exogenous cyclic AMP. Cyclic AMP relieved protease deficiency under carbon, nitrogen or sulfur limiting conditions to unequal extents. Protease stimulation was greatest under carbon-limited conditions, but the resulting growth was least. Most of the cyclic AMP-mediated increase of alkaline protease was extracellular.
Assuntos
Adenilil Ciclases/deficiência , AMP Cíclico/farmacologia , Neurospora crassa/enzimologia , Neurospora/enzimologia , Peptídeo Hidrolases/metabolismo , Neurospora crassa/genética , Fenótipo
2.
Rev. bras. pesqui. méd. biol
; Braz. j. med. biol. res;19(1): 27-32, 1986. tab
Artigo
em Inglês
| LILACS
| ID: lil-34606