RESUMO
OBJECTIVES: Prevalence of systemic sclerosis (SSc) and different clinical subsets varies across the world. Few data have been published on SSc patients in Latin America. Our objective was to describe a SSc cohort in Argentina and to compare clinical findings, disease subsets and antibodies with other international SSc populations. METHODS: Patients with SSc (n=234) seen at the Rheumatology section of the Hospital Italiano de Buenos Aires between 2000-2011 were retrospectively analysed. Data on clinical manifestations, disease subsets and antibodies were obtained. Patients were classified into diffuse cutaneous (dc) and limited cutaneous (lc) subsets. Comparison with other cohorts (France, United States, Germany, Italy, Mexico, EUSTAR and Brazil) was made based on published information. RESULTS: A higher female:male ratio (12:1) and a higher limited subset prevalence (76.1%) was found in this Argentine cohort comparing with others. We also found a lower prevalence of diffuse disease, anti Scl-70 (antitopoisomerase) and nucleolar pattern antinuclear antibodies. Within each subset, clinical findings were similar with other SSc populations except for a very low prevalence in renal crisis (0.02% of dc SS). CONCLUSIONS: With slight variations perhaps due to genetic, environmental or referral factors, SSc in this cohort appears to be similar to that described in other parts of the world.
Assuntos
Esclerodermia Difusa/epidemiologia , Esclerodermia Limitada/epidemiologia , Adulto , Idoso , Anticorpos Antinucleares/imunologia , Argentina/epidemiologia , Autoanticorpos/imunologia , Brasil/epidemiologia , Estudos de Coortes , DNA Topoisomerases Tipo I , Feminino , França/epidemiologia , Gastroenteropatias/epidemiologia , Alemanha/epidemiologia , Humanos , Hipertensão Pulmonar/epidemiologia , Itália/epidemiologia , Doenças Pulmonares Intersticiais/epidemiologia , Masculino , México/epidemiologia , Pessoa de Meia-Idade , Proteínas Nucleares/imunologia , Prevalência , Estudos Retrospectivos , Esclerodermia Difusa/imunologia , Esclerodermia Limitada/imunologia , Distribuição por Sexo , Estados Unidos/epidemiologiaRESUMO
Street-vendors in Mexico City provide ready-to-eat food to a high proportion of the inhabitants. Nevertheless, their microbiological status, general hygienic and trading practices are not well known. During spring and summer 2000, five tianguis (open markets) were visited and 48 vendors in 48 stalls interviewed. A total of 103 taco dressings were sampled for E. coli and Salmonella spp.: 44 (43%) contained E. coli and 5 (5%) Salmonella (2 S. Enteritidis phage type 8, 1 S. Agona, 2 S. B group). Both E. coli and salmonellas were isolated from three samples. Of Salmonella-positive stalls 80% (4/5) had three or more food-vendors and 80% of vendors were males, compared with 37.3% (16/43) and 46.4% (20/43) in the Salmonella-negative stalls respectively. Food-vendors kept water in buckets (reusing it all day), lacked toilet facilities, and prepared taco dressings the day before which remained at the tianguis without protection for 7.8 h on average. Consumption of street-vended food by local and tourist populations poses a health risk.
Assuntos
Infecções por Escherichia coli/transmissão , Escherichia coli/isolamento & purificação , Contaminação de Alimentos , Higiene , Infecções por Salmonella/transmissão , Salmonella/isolamento & purificação , Cidades , Comércio , Coleta de Dados , Escherichia coli/patogenicidade , Humanos , México , Prevalência , Saúde Pública , Medição de Risco , Salmonella/patogenicidade , Estações do AnoRESUMO
The street-vended food industry provides employment and cheap ready-to-eat meals to a large proportion of the population in developing countries like Mexico, yet little is known about its role in the transmission of food borne diseases (FBD). Because of its wide consumption, street-vended chili sauces in Mexico are potential vehicles of FBD. An observational study was performed in Mexico City collecting 43 street-vended chili sauces. These sauces were prepared under poor hygienic conditions of handling and selling. Consumers add 4-8 ml of chili sauce per taco, ingest 2-5 tacos per meal and on average, 50 consumers frequent a stall per day. Seventeen (40%) samples were faecally contaminated and 2(5%) sauces harboured sufficient enterotoxigenic Escherichia coli to cause disease. Weestimate that the consumption of only one of these chili sauces could result in ETEC disease inat least 21,000 consumers per year, making them important potential vehicles of FBD.
Assuntos
Escherichia coli/isolamento & purificação , Fezes/microbiologia , Microbiologia de Alimentos , Saúde Pública , Manipulação de Alimentos , Humanos , MéxicoRESUMO
A total of 100 free-living urban pigeons (Columba livia) were captured in the city of Santiago, Chile, in order to evaluate, for the first time, their health status. Negligible antibody titres (1 to 3 log2) were detected in 22% of the birds against a strain of the paramyxovirus (PMV) serotype 1. No pigeons had antibodies against PMV serotype 7 and avian influenza. Salmonella sp. belonging to serogroups B and D were isolated from the intestinal tract of three pigeons (3%). The protozoa Haemoproteus columbae, Plasmodium sp., and Leucocytozoon sp. were not detected in any pigeons. Trichomonas gallinae was detected in 11%, without observation of either clinical signs or gross pathological changes at necropsy. Sixty-seven percent of the birds showed the presence of the chewing lice Columbicola columbae and Campanulotes bidentatus compar, and 1% harboured the mite Laminosioptes cysticola. Seven species of nematodes were identified. The frequency at which each species was detected was; Tetrameres sp. (14%), Capillaria annulata (1%), Capillaria columbae (11%), Capillaria obsignata (1%), Ascaridia columbae (5%), Dispharynx spiralis (2%), and Gongylonema ingluvicola (2%). The class Cestoda, found in one pigeon, was represented by the species Aporina delafondi. No trematodes were detected in the sampled birds.
RESUMO
Se presenta la experiencia personal de los autores, que trabajan en tres centros hospitalario grandes de nuestra ciudad (Hosp. Oncologico y C.N.S., hOSP. Japones) en un numero de 85 casos de Cancer de Pene. Realizandose un analisis de presentacion de acuerdo a la edad, tiempo transcurrido desde la aparicion del tumor hasta la primera consulta, sus diferentes localizaciones, el astadiamento y el tipo histologico de los tumores. Finalmente se realiza un analisis de los resultados de acuerdo a los distintos tratamiento afectuados. Se hacen las consideraciones epidemiologicas para neustro medio y se trata de esbozar un protocolo de tratamiento, para aplicar en lo sucesivo.