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ABSTRACT Objective: To analyse pharmacological overlap in patients with autism spectrum disorder (ASD) under conscious sedation in a dental office environment, identifying any potential risks and complications. Material and Methods: A critical review was conducted by selecting articles from online databases (Pubmed and Lilacs), using a search algorithm and eligibility criteria. The Medscape® platform was used to verify interactions between drugs commonly used by patients with ASD and medications used for sedation in paediatric dentistry. Results: Due to their polydrug use, children with ASD are at risk of complications, namely Serotonin Syndrome (SS), Neuroleptic Malignant Syndrome (NMS), increase or decrease of the QT interval (QTi) and Torsade de Pointes (TdP), due to pre-existence of metabolic syndrome, deepening the sedation level or even leading to a decrease in the sedative capacity of the drugs used. Conclusion: It is essential to assess better drug interaction in ASD patients submitted to sedation. The severity of the disorder and the need for sedation for dental treatment are directly proportional. However, increases in sedative doses tend to increase risks and complications in children with ASD.

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ABSTRACT Objective: To assess the efficacy and safety of the use of midazolam as monotherapy, compared to the associated use of midazolam and hydroxyzine for minimum and moderate sedation of children in dental offices, using data obtained from clinical trials. Material and Methods: A systematic review protocol was developed and registered on PROSPERO (CR42020208633). An electronic search was carried out in Pubmed, Lilacs, Science Direct, Open Gray, Web of Science, and central Cochrane Library. No language restrictions were included. Clinical trials were carried out with children aged 0-12 years, using midazolam as monotherapy compared to the use of midazolam associated with hydroxyzine to verify the effectiveness and safety of oral sedation. The quality of the studies was individually assessed and grouped using the RoB 2 (Revised Cochrane risk-of-bias tool for randomized trials) and GRADE (Grading of Recommendations Assessment, Development and Evaluation) systems, respectively. Results: A total of 749 studies were found. After analyzing the inclusion and removal of duplicates, two studies were analyzed for the quality of evidence. Through this analysis, it was possible to verify the very low level of scientific evidence on the superiority of the efficacy and safety of the combined use of midazolam and hydroxyzine for oral sedation in children in dental offices. Conclusion: The conflicting results and limitations of the studies enabled to establish that there is insufficient evidence to support the use of these drugs combined. There is only evidence for the use of midazolam as monotherapy.

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ABSTRACT Objective: To evaluate the influence of non-invasive treatment associated with the use of infiltrating resin for managing caries lesions in primary teeth. Material and Methods: A systematic review was performed by selecting articles from 6 online databases, using a search algorithm and eligibility criteria for data extraction and data synthesis for the papers included. Clinical trials involving primary teeth with incipient caries lesions (1/2 of the enamel or 1/3 of the outer dentin) were included, presenting full text and answering the study's guiding question. This study used the RoB 2 tool for the risk of bias assessment and GRADE for certainty of evidence. Random effects meta-analyses were implemented, and lesion progression treatment effects were estimated through relative risk (RR) and associated 95% confidence intervals. Results: A total of 440 studies were found. After analyzing the inclusion criteria and removal of duplicates, eight studies were analyzed for quality evidence. Five of the eight studies included in this review contributed to the meta-analysis, all with some reflections regarding the risk of bias. Overall, the results of the meta-analysis showed that non-invasive treatment, when associated with the use of infiltrating resins, significantly reduced the risk of caries progression in relation to the treatment without this addition for follow-up periods ranging from 12 months to 2 years (RR 0.51 [0.40-0.65]). Conclusion: There is moderate certainty of evidence that the use of infiltrating resins associated with non-invasive treatments decreases the risk of caries progression in primary teeth with incipient caries lesions (1/2 of the enamel or 1/3 of the dentin outer) when combined with non-invasive control methods alone.

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ABSTRACT BACKGROUND AND OBJECTIVES: Musculoskeletal pain (MSP) is related to psychogenic factors and quality of sleep, showing that this triad is a biopsychosocial process. The aim of this study was to analyze an association between poor sleep quality and MSP in adolescents. METHODS: This study has an observational, cross-sectional character, in which 545 adolescents, aged between 11 and 15 years, were analyzed. Sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI), the presence of MSP using the Nordic Musculoskeletal Questionnaire (NMQ), temporomandibular disorder using the Axis II of the Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD) and excessive daytime sleepiness using the Epworth Sleepiness Scale (ESS). Pearson Chi-square or Fishers Exact test were used to assess the association between two categorical variables. RESULTS: The prevalence of poor sleep quality, sleep disorders, MSP and excessive daytime sleepiness were, respectively, 66.8, 9.5, 87.5 and 30.5%. An association was observed between the quality of sleep and the number of hours of sleep per night [OR = 1.49; (1.01 to 2.21)], and between sleep disorders and MSP in the upper back [OR=1.9; (1.0 to 3.3)], and the wrists and hands [OR=2.8; (1.4 to 5.7)]. However, there was no association between sleep quality and MSP [OR=1.29; (0.76 to 2.17)]. CONCLUSION: An association was found between sleep disorders and MSP, as well as between the number of hours slept per night and quality of sleep.

RESUMO JUSTIFICATIVA E OBJETIVOS: As dores musculoesqueléticas (DME) possuem relação com fatores psicogênicos e qualidade de sono, evidenciando que essa tríade se refere a um processo biopsicossocial. O objetivo deste estudo foi analisar a associação entre má qualidade de sono e DME em adolescentes. MÉTODOS: Realizou-se estudo observacional, com delineamento transversal, no qual foram analisados 545 adolescentes, na faixa etária entre 11 e 15 anos. A qualidade do sono foi avaliada através do Índice de Qualidade do Sono de Pittsburgh (PSQI), a presença de DME pelo Questionário Nórdico de Sintomas Osteomusculares (QNSO), disfunções temporomandibulares pelo Eixo II dos Critérios Diagnósticos de Pesquisa em Disfunção Temporomandibular (RDC/TMD) e a sonolência diurna excessiva através da Escala de Sonolência de Epworth (ESE). Para avaliar associação entre duas variáveis categóricas, foi utilizado o teste Qui-quadrado de Pearson ou o teste Exato de Fisher. RESULTADOS: A prevalência da má qualidade do sono, distúrbios do sono, DME e sonolência diurna excessiva foram 66,8, 9,5, 87,5 e 30,5%, respectivamente. Observou-se associação entre qualidade do sono e quantidade de horas de sono por noite [OR=1,49; (1,01 a 2,21)], e entre distúrbios do sono e DME na parte superior das costas [OR=1,9; (1,0 a 3,3)] e nos punhos e mãos [OR=2,8; (1,4 a 5,7)]. No entanto, não foi verificada associação entre qualidade do sono e DME [OR=1,29; (0,76 a 2,17)]. CONCLUSÃO: Foi verificada associação entre distúrbios de sono e DME, bem como entre qualidade do sono e quantidade de horas dormidas por noite.

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This systematic review of the literature assessed the effectiveness of using chewing gum containing only xylitol compared to prevention strategies or placebo in reducing the incidence of carious lesions in children using data obtained from randomized controlled trials. Electronic search was carried out in PubMed MEDLINE, Latin American and Caribbean Literature on the Health Science, Web of Science, Scopus, Science Direct, and Scientific Electronic Library Online through the period between 2000 and 2020. Included clinical studies were done in children when the xylitol was dispensed in gum and the preventive effect of xylitol on tooth decay was compared to other preventive strategies or control groups. The studies were evaluated for their quality to obtain the level of evidence. The preventive fraction of each study was extracted. Two hundred studies were found. After analyzing the inclusion and removal of duplicates, only five studies were analyzed for the quality of evidence. With the analysis through the Grading of Recommendations Assessment, Development, and Evaluation system, it was possible to verify the very low level of scientific evidence on the effectiveness of gums containing only xylitol for the prevention of caries in children. The preventive fraction obtained varied between - 0.31 and 0.57 depending on the compared prevention strategy. The conflicting results, limitations, and inconsistencies of the studies allow us to establish that there is insufficient evidence to support the use of gums containing only xylitol for the prevention of caries in children. Other properly designed clinical trials need to be carried out.

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ABSTRACT This paper discusses the potential risk that COVID-19 generates for the development of enamel defects. This hypothesis was built based on the etiopathogenesis of enamel defects and the relationship with the symptom's characteristic of COVID-19. Pregnancy is a critical period for the child's development; exposure to pathological agents can cause systemic imbalances and risks of adverse perinatal and prenatal outcomes. The main clinical symptoms of this disease and its association with that dental outcome were considered. Fever, breathing, cardiovascular disorders, and diarrhea were related as potential etiological factors of ameloblast metabolism imbalance, which can interfere qualitatively and quantitatively in the development, maturation and mineralization of the tooth enamel. Molecular disorders derived from COVID-19, as well as their clinical symptoms, can be considered potential risk factors for the development of enamel defects. Individuals with enamel defects experienced high stress levels during pregnancy or early childhood. The approach adopted may help build new research to ensure understanding of the etiology of the development of dental enamel defects and its relationship with COVID-19. However, longitudinal studies need to be conducted to confirm the association between COVID-19 and adverse events during pregnancy.

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Resumo Introdução O estudo da qualidade de vida de crianças portadoras de doenças crônicas, como o HIV, é essencial, visando um cuidado integral e holístico para os portadores da doença. Objetivo Avaliar a qualidade de vida e os fatores sociodemográficos associados de crianças portadoras do HIV. Método Estudo descritivo transversal, amostra de 78 crianças de ambos os sexos, faixa etária de 3 a 13 anos, atendidas em serviço de referência da cidade do Recife-PE. Foram utilizados o questionário Critério de Classificação Econômica Brasil, para caracterização socioeconômica, e a Escala de Qualidade de Vida da Criança (AUQEI). Para avaliar associação entre as variáveis, foram utilizados o teste Qui-quadrado de Pearson e o teste Exato de Fischer. A margem de erro utilizada foi de 5%. Resultados No tocante à qualidade de vida, ficar doente, brincar sozinho e a presença de bullying na escola apresentaram baixos índices de satisfação. Já itens como férias, aniversário, estar à mesa com a família e assistir televisão apresentaram altos níveis de satisfação. Conclusão As crianças desta pesquisa demonstraram uma qualidade de vida influenciada pelos aspectos negativos presentes em suas vidas. Desta forma, é necessária uma equipe multidisciplinar para o tratamento e prevenção de comorbidades, inclusive as psicossociais.

Abstract Background Studying the quality of life of children with chronic diseases, such as HIV, is essential, aiming at comprehensive and holistic care for people with the disease. Objective To assess the quality of life and sociodemographic associated factors in children with HIV. Method A descriptive cross-sectional study, with a sample of 78 children of both genders, aged between 3 and 13 years old, attending a reference service in the city of Recife-PE. Two questionnaires were used to collect data, the Brazilian Economic Classification Criteria questionnaire, to accomplish the socioeconomic characteristics, and the Quality of Life Scale for Children (AUQEI). Pearson's Chi-square test and Fisher's exact test evaluated the association between the variables. The margin of error was 5%. Results The quality of life, being sick, playing alone and the presence of bullying in school had low satisfaction rates. On the other hand, items such as vacations, birthday, being at the table with the family, and watching television showed high levels of satisfaction. Conclusions The children in this research demonstrated a quality of life influenced by the negative aspects present in their lives. Thus, a multidisciplinary team is needed for the treatment and prevention of comorbidities, including psychosocial ones.

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Purpose: to evaluate the impact of dental pain and the consequences of untreated dental caries on the quality of life in children of low social-economic status aged from 8 to 10 years old. Materials and Methods: in this cross-sectional study, 230 children were submitted to a clinical examination in which the caries-pufa ratio was measured, afterward, they answered to two questionnaires: one about their quality of life (CPQ8-10) and the other about dental pain. Data were statistically analyzed through Chi-square, Mann-Whitney or Kruskal-Wallis tests to evaluate the association between the variables with impact on children's OHRQoL. To establish the existence of risk factors among variables and impact on OHRQoL a Poisson Regression model was applied. Results: dental caries (p = 0.003; PR 2.39; 95% CI 1.04­1.56), severity of untreated caries (p = 0.008; PR 2.86; 95% CI 1.13­2.00), toothache (p < 0.001; PR 2.31; 95% CI 1.64­3.27) and PUFA + pufa index (p < 0.023; PR 2.68; 95% CI 1.10­1.87) were associated with and were a predictor factor for impact on overall OHRQoL. All of these variables also had an effect over the social welfare subscale (p ≤ 0.001), whereas caries presence was also statistically linked with the emotional wellbeing subscale (p = 0.008) and dental pain with all four subscales (p ≤ 0.001). Conclusion: untreated dental caries' clinical consequences and dental pain exerted a negative influence on the quality of life of schoolchildren analyzed.(AU)

Objetivo: avaliar o impacto da dor de dente e das consequências da cárie não tratada na qualidade de vida de crianças entre 8 e 10 anos com baixos indicadores socioeconômicos. Métodos: neste estudo transversal, 230 crianças escolares foram submetidas a um exame clínico, no qual foram avaliados seus CPO/ceo (Dentes cariados, perdidos e obturados) e PUFA/pufa (Envolvimento pulpar, ulceração, fístula e abscesso). Em um segundo momento, elas responderam a dois questionários: um sobre a qualidade de vida (CPQ8-10) e outro sobre odontalgia. Os dados foram analisados estatisticamente por meio dos testes de Chi-quadrado, Mann-Whitney ou Kruskal-Wallis, para avaliar a associação entre as variáveis e o impacto na qualidade de vida relacionada à saúde oral (QdVRSO) da criança. Para estabelecer a existência de fatores de risco para impacto na QdVRSO entre as variáveis, um modelo de regressão de Poisson foi aplicado. Resultados: a presença de cárie (p = 0,003; RP 2,39; 95% IC 1,04-1,56), a severidade da cárie não tratada (p = 0,008; RP 2,86; 95% IC 1,13-2,00), dor de dente (p < 0,001; RP 2,31; 95% IC 1,64-3,27) e PUFA/pufa (p < 0,023; RP 2,68; 95% IC 1,10- 1,87) foram associados com impacto na QdVRSO, assim como também foram fatores preditores para o impacto na qualidade de vida relacionada à saúde oral. Todas as então citadas variáveis também exerceram efeito sobre a subescala do bem-estar social (p ≤ 0,001), enquanto a presença de cárie esteve estatisticamente conectada com a subescala do bem-estar emocional (p = 0,008) e a dor dentária com todas as subescalas da QdVRSO (p ≤ 0,001). Conclusão: as consequências clínicas da cárie não tratada e a dor dentária exercem uma influência negativa na qualidade de vida das crianças analisadas.(AU)

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Abstract Objective: To develop an educational mobile application as a dynamic platform provided free of charge, including several clinical and laboratory protocols for a wider range of skills and greater knowledge on the strategic axes of child dental care: Pediatric Dentistry and Orthodontics. Material and Methods: The prototype tool was structured as follows: development of clinical and laboratory contents to be addressed, software selection, layout format, inclusion of features, applicability and acceptability tests of the operational system, and indexation on the Play Store® application store (free of charge). Results: The mobile application has shown to be a tool capable of storing and providing data through various audiovisual media formats on clinical and laboratory contents of child dental care. Media resources were developed for the following themes: restorative dentistry in pediatric dentistry, radiographic techniques with pediatric patients, pulp therapy in deciduous teeth, traumatic injuries in the primary dentition, and preventive and interceptive orthodontics. The short-duration multimedia content, with different audiovisual formats, proved to be coherent with the peculiarities of each procedure, enabling to better visualize and understand the techniques. Moreover, the rewind, fast forward, and pause features were included in the mobile application, as well as the possibility of saving print screens, as well as highlighting and searching for contents of interest. Conclusion: The OdontoPed-Helpbox® demonstrated to be able to reach new strategies for the dynamic teaching-learning process, through operational efficiency. It proved to be a useful and instant tool for providing information to support clinical decision making in Dentistry.

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Abstract Objective: To evaluate sleep quality and excessive daytime sleepiness in undergraduate dentistry students. Material and Methods: This research is characterized as an observational study of transversal type, having analysed undergraduate students in dentistry from a public university in the State of Pernambuco, Brazil. The sample consisted of 325 students enrolled between the 1st and 10th academic semester. Sleep quality was evaluated using the Pittsburgh Sleep Quality Index (PSQI), while excessive daytime sleepiness was analysed through the Epworth Sleepiness Scale (ESS). The t-Student and Mann-Whitney tests were used for the numerical values, with the F-test (ANOVA) or the Kruskal-Wallis test being used to compare more than two categories. Results: It was observed that 71.1% of students presented a poor sleep quality, with more than half of the students exhibiting excessive daytime sleepiness (58.1%). A relationship between sleep quality and the academic semester was verified. However, gender and age were not associated with sleep quality or with excessive daytime sleepiness. Conclusion: A high prevalence of poor sleep quality and excessive daytime sleepiness was observed among undergraduate students in dentistry. The data suggest that the undergraduate degree in Dentistry can influence the students' quality of sleep, regardless of age or gender.

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Introduction: Dental trauma in childhood is a serious and high incidence complication, mostly due to the discovery phase. This is when the first steps begin, without adequate motor coordination, making children more prone to falls. Trauma to a deciduous tooth can leave sequelae owing to the anatomical proximity to the permanent successor tooth germ. Objective: This study aimed to report a case of severe intrusion in a 10-month-old baby with the emergence of odontoma after dental trauma. Case Report: A 9-year-old patient, accompanied by the guardian, sought attendance for delayed primary teeth exfoliation. During anamnesis, the trauma to the deciduous dentition was found in a 10-month old child, followed by clinical and radiographic examination, showing the presence of odontoma in teeth 11 and 21. The multidisciplinary treatment plan included surgery to remove the odontoma, with subsequent rehabilitation. Conclusion: Trauma to primary dentition can have several consequences for permanent dentition. Thus, dental care is required soon after the incident, besides careful follow-up to evaluate possible sequelae.

Introdução: O traumatismo dentário na infância é uma intercorrência grave, de incidência alta devido principalmente a fase de descobertas, com o início dos primeiros passos, sem ter coordenação motora adequada, tornando as crianças mais propensas a quedas. Um trauma em um dente decíduo pode deixar sequelas em razão da proximidade anatômica ao germe do dente sucessor permanente. Objetivo: O objetivo deste trabalho foi relatar um caso de intrusão grave em bebê de 10 meses, com surgimento de Odontoma após trauma dentário. Relatode Caso: Paciente de 9 anos de idade, acompanhada pela responsável, procurou atendimento pelo atraso na esfoliação dos dentes decíduos. Durante a anamneses foi constatado traumatismo na dentição decídua aos 10 meses de idade, e em seguida realizado o exame clínico e radiográfico, demostrando a presença de odontoma nos dentes 11 e 21. O plano de tratamento multidisciplinar compreedeu a cirurgia para remoção do odontoma, com posterior tratamento ortodôntico reabilitador. Conclusão: O trauma na dentição decídua pode gerar diversas consequências para a dentição permanente. Desse modo é necessário um atendimento odontológico logo após o incidente e um proservação do caso, para avaliar possíveis sequelas.

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Objetivo: avaliar a confiabilidade de fórmulas para o cálculo da dose dos principais antibacterianos em crianças de diferentes idades e pesos, tendo como padrão-ouro as dosagens fornecidas em bulas. Sujeitos e método: 45 crianças, com idades de 3, 6 e 9 anos, constituíram três grupos independentes. Os dados antropométricos foram obtidos por meio da análise de prontuários da Clínica de Odontologia Infantil da Faculdade Integrada de Pernambuco. As dosagens foram calculadas através das fórmulas estabelecidas a partir de parâmetros de peso, idade e superfície corporal. Os antibacterianos selecionados para a análise foram: Amoxicilina, Amoxicilina com clavulonato de potássio, Clindamicina, Claritromicina, Eritromicina e Azitromicina. Os dados foram submetidos ao teste paramétrico de análise de variância. Para verificar se houve diferença entre as dosagens estabelecidas por fórmulas e a dose estabelecida pela bula (padrão-ouro), foi aplicado o teste post-hoc de Tukey. Os testes estatísticos foram realizados com uma margem de erro de 5%. Resultados: nenhuma fórmula foi válida para todos os antibacterianos quando se comparou com a dose padrão estabelecida em bula. Os resultados apresentaram maiores variabilidades no grupo de crianças com menor idade, podendo ser considerado um risco clínico. Conclusão: as dosagens pediátricas dos antibacterianos obtidas por meio de fórmulas não são confiáveis para os grupos etários analisados e, portanto, não devem ser utilizadas para fins de prescrição medicamentosa. (AU)

Objective: This cross-sectional study evaluated the reliability of formulas for calculating the dose of the main antibacterials in children of different ages and weight, and the gold standard were the dosages provided in package inserts. Subjects and method: Forty-five children aged 3, 6, and 9 years constituted three independent groups. The anthropometric data were obtained through the analysis of medical records of the Child Dentistry Clinic of Faculdade Integrada de Pernambuco, Brazil. The dosages were calculated using the formulas established from parameters of weight, age, and body surface. The antibacterials selected for this analysis were amoxicillin, amoxicillin with potassium clavulanate, clindamycin, clarithromycin, erythromycin, and azithromycin. The data were subjected to parametric analysis of variance. In order to verify whether there was a difference between the dosages established in the formulas and the dose established in the package insert (gold standard), Tukey's post-hoc test was applied. The statistical tests were performed with a 5% margin of error. Results: No formula was valid for all antibacterials when compared to the standard dose established in package inserts. The results showed greater variability in the group of younger children, which may be considered a clinical risk. Conclusion: The pediatric dosages of antibacterials obtained in formulas are not reliable for the age groups analyzed and therefore should not be used for drug prescription purposes. (AU)

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Introduction: Ameloblastic fibrodentinoma (AFD) is a rare, asymptomatic, slow-growing mixed odontogenic tumor, usually affecting children and young peoplein their first or second decade of life. This lesion usually causes bone expansion ofthe involved region and makes tooth eruption difficult. Objective: the aim of thisstudy is to report a case of AFD in the anterior maxilla of a 3-year-old baby and itstreatment, highlighting the importance of early dental care and treatment forthis type of injury. Casereport: A 3-year-old female patient attended the dentalcare clinic at Cesmac University Center (Maceió- AL, Brazil), accompanied by hermother, reporting a swollen gum for approximately 6 months. Clinical examinationrevealed an increase in volume in the right central and lateral incisor region,discreetly reddish in color, smooth surface, spherical shape, sessile insertion, nomobility and firm consistency. Radiographic examination revealed a mixed lesionwith radiolucent area compatible with bone resorption and radiopaque areascompatible with calcified material within the lesion. An incisional biopsy wasperformed, confirming the diagnosis of Ameloblastic Fibrodentinoma. Conclusion:Treating this anomaly requires an early approach to improve the quality of life ofthese patients. Parents or guardians should be advised of the need for periodicfollow-up after treatment.

Introdução: O Fibrodentinoma Ameloblástico (FDA) é um tumor odontogênicomisto, raro, assintomático e de crescimento lento, acometendo normalmentecrianças e jovens em sua primeira ou segunda década de vida. Essa lesãogeralmente provoca expansão óssea da região envolvida e dificulta a erupçãodentária. Objetivo: O objetivo deste trabalho é relatar um caso de FDA em maxilaanterior de bebê de 3 anos de idade e seu tratamento, ressaltando a importânciado atendimento odontológico precoce e o tratamento para este tipo de lesão.Relatodecaso: Paciente do gênero feminino, 3 anos, compareceu à clínicaodontológica de atendimento a bebês do Centro Universitário Cesmac (Maceió ­AL, Brasil), acompanhada de sua mãe, relatando uma gengiva inchada háaproximadamente 6 meses. Ao exame clínico, observou-se um aumento de volumena região do incisivo central e lateral direito, com coloração discretamenteavermelhada, superfície lisa, formato esférico, com inserção séssil, sem mobilidadee de consistência firme. Ao exame radiográfico constatou-se uma lesão mistacom área radiolúcida compatível com reabsorção óssea e áreas radiopacascompatíveis com material calcificado no interior da lesão. Foi realizado umabiopsia incisional, confirmando o diagnóstico de Fibrodentinoma Ameloblástico.Conclusão: O tratamento desta anomalia requer uma abordagem precoce como objetivo de melhorar a qualidade de vida desses pacientes, devendo-se aconselharos pais ou responsáveis quanto à necessidade do acompanhamento periódicoapós a realização do tratamento.

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An experimental dentifrice containing nano-silver fluoride (NSF) and a sodium fluoride (NaF) toothpaste were tested in vitro, against S. mutans, to evaluate the minimal inhibitory concentration (MIC), minimal bactericidal concentration (MBC), antiadherence, antiacid, enamel microhardness, and OCT. The microdilution technique was used to determine the MIC and MBC. Fragments of deciduous enamel were treated with dentifrice slurries, containing bacterial suspension and PBS-treated saliva. The quantification of the microorganisms that adhered to the enamel was determined after 24 hours of incubation, and media pH readings were performed after 2 hours and 24 hours. Deciduous teeth were evaluated for microhardness and OCT during 14 days of pH cycling. Data were statistically analyzed using Student's t-test, Mann-Whitney U test, ANOVA, and Tukey tests at 5% of significance. Dentifrices containing NSF presented a lower MIC and higher statistically significant results compared to NaF dentifrices with respect to preventing bacterial adhesion and pH decreases. NSF and NaF dentifrices showed the same ability to avoid enamel demineralization corroborated by the OCT images. The NSF formulation had a better antibacterial effect compared to NaF dentifrices and similar action on the demineralization of enamel indicating their potential effectiveness to prevent caries.

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OBJECTIVES: This in vivo research investigated whether pulp treatments using formocresol for 7 days would cause mutagenic changes in children's lymphocytes. MATERIALS AND METHODS: The mutagenicity was tested in lymphocyte cultures established from the peripheral blood of children living in Brazil. The samples consisted of 2000 cells from teeth undergoing formocresol pulpotomies in which the formocresol pellet was sealed in the primary tooth for 7 days. It was removed on the seventh day, the base was placed, and the tooth was restored. Two venous blood samples (6-8 ml) were collected from each child; the first was prior to pulp therapy, and the second was 7 days later. Two thousand metaphases were analyzed. The level of significance adopted for the statistics was P < 0.05, and a random effects meta-analysis was performed combining this and two previous studies. RESULTS: There was no significant difference found in the metaphase analysis between the blood samples taken before and after the pulpotomy treatment (Wilcoxon signed rank test); however, the meta-analysis showed a significant difference between the combined studies. CONCLUSIONS: This study did not reveal any mutagenic effects, but based on the combined meta-analysis, we recommend the careful use of formocresol. CLINICAL RELEVANCE: This research helps to bring scientific evidence of the safe use of formocresol in deciduous pulpotomy treatments.

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Introduction: malocclusions are considered public health problems, needing an uniform method of assessment that prioritizes the attendance of individuals with greater orthodontic treatment need, with this purpose, the Index of Orthodontic Treatment Need has been used in many countries. Objetive: to evaluate the orthodontic treatment need in school going children, attending in Recife, northeast Brazil and also establishes its relationship with gender, family income and ethnic groups. Methods: 433 children, aged 6-12 years formed the sample. The dental health component grades it was recorded to define the orthodontic treatment need. Results: the findings revealed that 59.5 % of children had at least one type of malocclusion; 40.5 % had no need for orthodontic treatment (grade 1 and 2); 5.5 % were borderlines, indicating moderate need (grade 3); 54 % had definite treatment (grade 4), but no children were classified in grade 5. No statistically significant differences were found between genders (p= 0.217), family income (p= 0.176) and ethnic groups (p= 0.281). Conclusion: the most of the children had moderate and great orthodontic needs treatment. There was no association between orthodontic treatment need and gender, family income or ethnic groups(AU)

Introducción: las maloclusiones se consideran un problema de salud pública, que requiere un método uniforme de evaluación que priorice la asistencia de las personas con mayores necesidades de tratamiento de ortodoncia, para este fin, el Índice de Necesidad de Tratamiento Ortodóncico se ha utilizado en muchos países. Objetivo: evaluar la necesidad de tratamiento ortodóncico en niños en edad escolar que viven en Recife, noreste de Brasil, y establecer su relación con el género, el ingreso familiar y los grupos étnicos. Métodos: 433 niños de 6 a 12 años conformaron la muestra. Los datos obtenidos en el componente de salud dental fueron recodificadas para definir la necesidad del tratamiento ortodóncico. Resultados: los resultados revelaron que 59,5 % de los niños tienen al menos un tipo de maloclusión; 40,5 % no tenía necesidad de tratamiento de ortodoncia (grado 1 y 2); 5,5 % tenía una condición de frontera, lo que indica la necesidad moderada (grado 3); 54 % tenían un tratamiento definitivo (grado 4), y no hubo niños clasificados en el grado 5. No se encontraron diferencias estadísticamente significativas entre sexos (p= 0,217), ingreso familiar (p= 0,176) y los grupos étnicos (p= 0,281). Faculty of Dentistry: La mayoría de los niños tenían necesidad de tratamiento ortodóncico moderada o grande. No hubo asociación entre la necesidad de tratamiento de ortodoncia y el sexo, ingresos o grupos étnicos(AU)

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RESUMO

Objetivo: o objetivo deste trabalho é realizar um levantamento dos estudos publicados de 2004 a 2014 sobre o impacto da deficiência de vitamina D na prevalência de cárie precoce na infância. Método: a estratégia de busca das publicações incluiu as bases de dados Medline, Lilacs e Pubmed. A seleção dos artigos foi feita com base nos seguintes critérios: ter sido escrito em inglês, espanhol ou português; apresentar resumo estruturado e abordar aspectos que relacionem a deficiência de vitamina D com cárie dentária em crianças. Após a análise crítica dos resumos, sete estudos foram selecionados. Considerações finais: há clara associação entre deficiência de vitamina D e cárie precoce na infância. Além disso, a literatura atual sugere que a suplementação de vitamina D pode reduzir o risco do desenvolvimento de lesões cariosas.

RESUMO

Objetivo: Avaliar se os critérios radiográficos clássicos de indicação de terapia pulpar em dentes decíduos vêm sendo observados no cotidiano das atividades clínicas. Método: Foram avaliados 359 prontuários de pacientes atendidos na clínica de odontopediatria da Faculdade de Odontologia de Pernambuco (FOP/UPE), no período de janeiro de 2011 a junho de 2013. Dentre os 359 prontuários avaliados, 64 registraram tratamento pulpar em 78 dentes decíduos, os quais compõem a amostra final deste estudo. Mediante as radiografias intraorais, contidas nos prontuários, foram observados o grau de destruição coronária, o estágio de desenvolvimento de Nolla da raiz do sucessor permanente e o grau de rizólise do dente decíduo. Resultados: observou-se que a idade média das crianças incluídas no estudo foi de 6,62 anos (± 1,98). Em 11,5% dos casos, o critério que previa condições para que o dente decíduo pudesse ser restaurado não foi seguido, e em 32% dos casos não foram levados em consideração o grau de rizólise do dente decíduo ou o estágio de Nolla. Conclusão: Os critérios radiográficos clássicos de indicação para terapia pulpar em dentes decíduos não estão sendo rigorosamente observados na clínica odontopediátrica da instituição de ensino avaliada, indicando o risco de iatrogenias serem reproduzidas pelos futuros profissionais.

Aim: To assess whether the radiographic classic criteria of pulp therapy indication in deciduous teeth have been observed in daily clinical activities. Methods: A total of 359 records of patients attended in pediatric dentistry clinic of the Faculty of Dentistry of Pernambuco (FOP / UPE), from January 2011 to June 2013. Of the 359 records evaluated 64 registered pulp treatments in 78 primary teeth, which make up the final sample. Through intra-oral radiographs, contained in the medical records, the degree of coronary destruction, the Nolla stage of development of the permanent successor root and the degree of tooth root resorption deciduous were observed. Results: It was observed that the average age of the children included in the study was 6.62 years (± 1.98). In 11.5% of cases, the criterion which provided conditions for the deciduous tooth could be restored was not followed, and in 32% of cases were not taken into account the degree of tooth root resorption deciduous or Nolla stage. Conclusion: The classic radiographic criteria indication for pulp therapy in primary teeth, are not being strictly observed in Pediatric Dentistry of assessed educational institution, indicating the risk of iatrogenic be reproduced by future professionals.

RESUMO

Objective: to evaluate the tendency and polarization of dental caries in children 4-5 years of age, between 2006 and 2014. Method: this is a comparison of two similar cross-sectional studies that included 226 children each year. Clinical data were collected according to the criteria proposed by the World Health Organization (WHO). A previously validated questionnaire was administered to parents or guardians of children, in order to obtain data related to family income. Results: 32.7 percent of children in 2006 and 35 percent in 2014 had at least one decayed tooth. The dmft index was 1.25 in 2006 and 1.40 in 2014, with no statistically significant difference (p> 0.05). It was verified that there is a higher concentration of dental caries in populations of lower economic status (p <0.05) for the years of analysis. Conclusion: the caries prevalence showed a tendency to remain constant after eight years of the baseline. Thus, the disease showed polarized, indicating a higher concentration of children whose families had worse socioeconomic conditions(AU)

Objetivo: evaluar la tendencia y la polarización de la caries dental en niños de 4-5 años de edad, entre 2006 y 2014. Método: se trata de la comparación de dos estudios transversales similares que incluyó a 226 niños en cada año. Los datos clínicos fueron recogidos de acuerdo con los criterios propuestos por la Organización Mundial de la Salud (OMS). un cuestionario previamente validado, fue aplicado a los padres o responsables de los niños, con la finalidad de obtener datos relacionados con los ingresos financieros familiar. Resultados: el 32,7 por ciento de los niños en 2006 y 35 por ciento en el 2014, tenían al menos un diente cariado. El índice ceod en 2006 fue de 1,25 y en 2014, de 1,40, no se encontró diferencia estadísticamente significativa (p> 0,05). Fue verificado que hay una mayor concentración de caries dental en poblaciones de menor estatus económico (p<0,05) para los años de análisis. Conclusión: la prevalencia de caries dental presentó una tendencia a mantenerse constante después de ocho años del momento de la evaluación inicial. Con esto, la enfermedad se mostró polarizada, evidenciando una mayor concentración en niños cuya familia poseía peores condiciones socioeconómicas(AU)

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