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1.
Cir Cir ; 85 Suppl 1: 89-92, 2017 Dec.
Artigo em Espanhol | MEDLINE | ID: mdl-27955849

RESUMO

BACKGROUND: The gallbladder volvulus is defined as the rotation of the gallbladder on its mesentery along the axis of the cystic duct and cystic artery. It is an extremely rare surgical disease and definitive diagnosis is usually made during surgery. CASE REPORT: A 78 year old woman presented with upper right quadrant abdominal pain, with no comorbidities and no other accompanying symptoms. Analysis revealed haemodynamic instability and leukocytosis. Computed tomography of abdomen showed an acute cholecystitis. During emergency right hypochondrium laparotomy, the gallbladder was found to be twisted counterclockwise with huge gangrenous gallbladder distal. Open cholecystectomy was performed and after the surgery, the patient was discharged in a few days. CONCLUSION: Gallbladder volvulus, or gallbladder torsion, is a rare condition and should be considered when clinical and imaging findings of complicated cholecystitis are present. The performance of urgent laparoscopic surgery would be first option to avoid perforation, peritonitis and haemodynamic instability.


Assuntos
Colecistectomia/métodos , Doenças da Vesícula Biliar/diagnóstico por imagem , Doenças da Vesícula Biliar/cirurgia , Anormalidade Torcional/diagnóstico por imagem , Anormalidade Torcional/cirurgia , Idoso , Colecistite/diagnóstico por imagem , Colelitíase/diagnóstico por imagem , Erros de Diagnóstico , Emergências , Feminino , Vesícula Biliar/patologia , Gangrena , Humanos , Laparotomia , Necrose , Tomografia Computadorizada por Raios X
2.
Clin Transl Oncol ; 7(3): 101-9, 2005 Apr.
Artigo em Espanhol | MEDLINE | ID: mdl-15899217

RESUMO

Colorectal cancer is one of the best studied of all malignant diseases in terms of genetics and/or molecular prognostic factors. These factors, and relationships with prognosis, may have important implications especially in the design of surgical and adjuvant chemo-radiotherapy options. However, the true prognostic significance of all known factors has yet to be realised. We have reviewed the literature with specific focus on the role of molecular markers involved in prognosis and the prediction of response to adjuvant treatment.


Assuntos
Neoplasias Colorretais/genética , Neoplasias Colorretais/terapia , Apoptose/genética , Biomarcadores Tumorais/análise , Terapia Combinada , Humanos , Mutação , Oncogenes , Prognóstico
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