RESUMO
BACKGROUND: Sleeve gastrectomy is a well-standardized surgical treatment for obesity. However, rates of weight regain after sleeve gastrectomy in long-term follow-up are relatively high. This multicenter study is the first to evaluate the use of an endoscopic sleeve gastroplasty (ESG) technique for the management of this population. METHODS: This was a multicenter retrospective study, including patients with weight regain following sleeve gastrectomy who underwent ESG for weight loss. Primary outcomes included absolute weight loss, percent total weight loss (%TWL), change in body mass index (BMI), percent excess weight loss (%EWL) at 6 and 12 months, and safety profile. Clinical success was defined as achieving ≥â25â% EWL at 1 year, ≤â5â% serious adverse event (SAE) rate following society-recommended thresholds, and %TWL ≥â10â%. RESULTS: 34 patients underwent ESG after sleeve gastrectomy. Technical success was 100â%. At 1 year, 82.4â% and 100â% of patients achieved ≥â10â%TWL and ≥â25â% EWL, respectively. Mean (SD) %TWL was 13.2â% (3.9) and 18.3â% (5.5), and %EWL was 51.9â% (19.1) and 69.9â% (29.9) at 6 months and 1 year, respectively. Mean (SD) %TWL was 14.2â% (12.5), 19.3â% (5.3), 17.5â% (5.2), and 20.4â% (3.3), and %EWL was 88.5â% (52.8), 84.4â% (22.4), 55.4â% (14.8), and 47.8â% (11.2) for BMI categories of overweight and obesity class I, II, and III, respectively, at 1 year. No predictors of success were identified in the multivariable regression analysis. No SAEs were reported. CONCLUSION: ESG appears to be safe and effective in the management of weight regain following sleeve gastrectomy.