RESUMO
An epidemiological survey on goiter was conducted in Buenos Aires, on 3882 schoolchildren, a randomized sample of 160,026 children of public schools, before establishing prophylactic measures in 1968. With an estimated error of 5% the result was 14.8% of goiter prevalence. This figure qualified Buenos Aires as an endemic area and was, therefore, included in the National Programme to Combat Endemic Goiter, through iodized salt (proportion 1:30,000 of salt). Schools were qualified according to their social level in high, middle and low; the prevalence of goiter was 6.8%, 12.2% and 26.4%, respectively. The prevalence was also higher in older ages. In 1986, using the same randomized sample, a second survey was conducted, after 18 years of prophylaxis. Goiter prevalence was 8.5%. Goiter in the low social class was about the same as in the middle class. In randomized samples of 49 urines, iodine concentration was determined yielding an average of 139.6 micrograms/g creatinine (median 120.9 micrograms/g creatinine). Urinary iodine level in 14 children with goiter was 146.1 micrograms/g creatinine and in 12 without goiter was 171.4 micrograms/g. There was no statistical difference between these three groups. Variations in radioiodine uptake, urinary iodine, plasma inorganic iodine levels, and water iodine are discussed.
Assuntos
Bócio Endêmico/epidemiologia , Adolescente , Fatores Etários , Argentina/epidemiologia , Criança , Creatinina/urina , Feminino , Bócio Endêmico/prevenção & controle , Bócio Endêmico/urina , Humanos , Iodo/administração & dosagem , Iodo/urina , Masculino , Análise de Regressão , Estudos de Amostragem , Fatores Sexuais , Fatores Socioeconômicos , Sódio na Dieta/administração & dosagem , População UrbanaRESUMO
Se presentan los resultados de dos encuestas de bocio efectuadas en Buenos Aires, una en 1968, anterior a la prifilaxis con sal yodada y la otra en 1986, durante su aplicación. La prevalencia de bocio fue de 14,8% y 8.5% respectivamente, siendo estadísticamente significativa la diferencia. La medida de las yodurias pasó de 92,7 µg/24 hs a 139,6 µg/g creatinina. Otros parámetros tiroides muestran diferencias definidas, indicando todos mayor contenido de yodo en el organismo. En 1968 había una asociación estadísticamente definida entre bocio y el nivel social del alumnado, que era de 6,8% en el alto, 12,2% en el medio y 26,4% en el bajo; en 1986 no se halló diferencia por nivel social. Tampoco se halló diferencia por sexo, pero se halló correlación con la edad, en ambas encuestas
Assuntos
Criança , Adolescente , Humanos , Masculino , Feminino , Bócio Endêmico/epidemiologia , Fatores Etários , Argentina/epidemiologia , Creatinina/urina , Bócio Endêmico/prevenção & controle , Iodo/administração & dosagem , Iodo/urina , Análise de Regressão , Estudos de Amostragem , Fatores Sexuais , Fatores Socioeconômicos , Sódio na Dieta/administração & dosagem , Sódio na Dieta/farmacologiaRESUMO
An epidemiological survey on goiter was conducted in Buenos Aires, on 3882 schoolchildren, a randomized sample of 160,026 children of public schools, before establishing prophylactic measures in 1968. With an estimated error of 5
the result was 14.8
of goiter prevalence. This figure qualified Buenos Aires as an endemic area and was, therefore, included in the National Programme to Combat Endemic Goiter, through iodized salt (proportion 1:30,000 of salt). Schools were qualified according to their social level in high, middle and low; the prevalence of goiter was 6.8
, 12.2
and 26.4
, respectively. The prevalence was also higher in older ages. In 1986, using the same randomized sample, a second survey was conducted, after 18 years of prophylaxis. Goiter prevalence was 8.5
. Goiter in the low social class was about the same as in the middle class. In randomized samples of 49 urines, iodine concentration was determined yielding an average of 139.6 micrograms/g creatinine (median 120.9 micrograms/g creatinine). Urinary iodine level in 14 children with goiter was 146.1 micrograms/g creatinine and in 12 without goiter was 171.4 micrograms/g. There was no statistical difference between these three groups. Variations in radioiodine uptake, urinary iodine, plasma inorganic iodine levels, and water iodine are discussed.
RESUMO
Se presentan los resultados de dos encuestas de bocio efectuadas en Buenos Aires, una en 1968, anterior a la prifilaxis con sal yodada y la otra en 1986, durante su aplicación. La prevalencia de bocio fue de 14,8% y 8.5% respectivamente, siendo estadísticamente significativa la diferencia. La medida de las yodurias pasó de 92,7 Ag/24 hs a 139,6 Ag/g creatinina. Otros parámetros tiroides muestran diferencias definidas, indicando todos mayor contenido de yodo en el organismo. En 1968 había una asociación estadísticamente definida entre bocio y el nivel social del alumnado, que era de 6,8% en el alto, 12,2% en el medio y 26,4% en el bajo; en 1986 no se halló diferencia por nivel social. Tampoco se halló diferencia por sexo, pero se halló correlación con la edad, en ambas encuestas (AU)