RESUMO
Liposarcoma of the lung is extremely rare with only 11 cases previously reported. A case of a locally advanced pulmonary pleomorphic liposarcoma in a 49-year-old male is presented. Surgery was performed but radical resection was not possible. Post-operative radiotherapy (40 Gy) was given concurrently with cisplatin (12.5 mg daily for 10 days). A partial response of short duration was obtained. The patient died 8 months following surgery with disseminated disease. Based on reports in the literature, liposarcoma of the lung must be classified as an aggressive highly metastatic disease responding poorly to both chemotherapy and radiotherapy.
Assuntos
Lipossarcoma/diagnóstico , Neoplasias Pulmonares/diagnóstico , Quimioterapia Adjuvante , Cisplatino/administração & dosagem , Evolução Fatal , Humanos , Lipossarcoma/terapia , Neoplasias Pulmonares/terapia , Masculino , Pessoa de Meia-IdadeRESUMO
The use of growth hormone (GH) has been implicated as a possible risk factor for leukemia. We present data from six patients that support a working hypothesis that an increased risk of leukemia may exist in patients with GH deficiency not related to exogenous use of GH.