Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 1 de 1
Filtrar
Mais filtros











Base de dados
Intervalo de ano de publicação
1.
Vet Parasitol ; 180(3-4): 368-71, 2011 Aug 25.
Artigo em Inglês | MEDLINE | ID: mdl-21466920

RESUMO

Toxoplasma gondii causes fatal multisystemic disease in New World primates, with respiratory failure and multifocal necrotic lesions. Although cases and outbreaks of toxoplasmosis have been described, there are few genotyping studies and none has included parasite load quantification. In this article, we describe two cases of lethal acute toxoplasmosis in squirrel monkeys (Saimiri sciureus) of Mexico city. The main pathological findings included pulmonary edema, interstitial pneumonia, hepatitis and necrotizing lymphadenitis, and structures similar to T. gondii tachyzoites observed by histopathology in these organs. Diagnosis was confirmed by immunohistochemistry, transmission electron microscopy and both end point and real time PCR. The load was between <14 and 23 parasites/mg tissue. Digestion of the SAG3 gene amplicon showed similar bands to type I reference strains. These are the first cases of toxoplasmosis in primates studied in Mexico, with clinical features similar to others reported in Israel and French Guiana, although apparently caused by a different T. gondii variant.


Assuntos
Atelinae , Doenças dos Macacos/parasitologia , Toxoplasmose Animal/epidemiologia , Doença Aguda , Animais , Evolução Fatal , México/epidemiologia , Doenças dos Macacos/epidemiologia , Doenças dos Macacos/patologia , Toxoplasmose Animal/patologia
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA