RESUMO

The scientific basis for the statement that plants and their active constituents play an important role in the prevention of chronic and degenerative diseases is continously advancing. The object of the present study was to evaluate the effect of Hibiscus sabdariffa L. dried calyx ethanolic extract on the serum lipid profile of Sprague-Dawley rats. The rats were fed during 4 weeks with either a basal diet, containing high cholesterol (1%), cholic acid (0.25%), lard oil (10%), or a supplemental diet with H. sabdariffa extract at 5%, 10%, and 15% levels (SD(5), SD(10), SD(15)). Weight gain and faeces dry weight were both very significantly less (p

Assuntos

Colesterol/sangue , Hibiscus/química , Lipídeos/sangue , Extratos Vegetais/administração & dosagem , Triglicerídeos/sangue , Aumento de Peso/efeitos dos fármacos , Animais , LDL-Colesterol/sangue , Relação Dose-Resposta a Droga , Fezes , Masculino , Distribuição Aleatória , Ratos , Ratos Sprague-Dawley , Triglicerídeos/biossíntese