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Background: Due to their abundant vascular supply, the lungs are a usual metastatic site, with primary lung cancer presenting a low prevalence in dogs and cats. Among the primary pulmonary tumors afflicting dogs, lepidic carcinoma is the mostcommon and can be classified by site of onset. Lepidic predominant adenocarcinoma is characterized by the proliferationof neoplastic cells along the pulmonary alveoli and pre-existing alveolar structures. Few reports of this specific tumor werefound in the literature, so the objective of this study is to describe the clinical, pathological, and immunohistochemicalfindings of a dog with predominantly diffuse lepidic adenocarcinoma.Case: A 14-year-old, female, spayed, mixed-breed canine with a history of progressive weight loss, cough, respiratorydistress, and pain while eating was brought in for a consultation. A presumptive diagnosis of pneumonia was suggested.However, in spite of treatment, the dog died, and a necropsy was performed. Upon gross examination, the lungs were diffuselyenlarged, whitish, and stiffened with large and highly vascular nodules. Histopathological findings showed proliferation ofneoplastic cells along the vascular walls and within the bronchioalveolar structures, with moderate fibrovascular stroma.The growth patterns resembled the pre-existing alveolar structures, with papillary protrusions into the alveolar lumen.After immunohistochemical evaluation, the definitive diagnosis was diffuse lepidic predominant adenocarcinoma. Thistumor is uncommon and difficult to diagnose in the clinical veterinary routine, so it should be considered in the differentialdiagnosis of respiratory conditions in canines, especially in elderly animals with chronic clinical signs not responsive toantibiotic therapy. Complementary diagnostic examinations such as imaging, laboratory tests, and biopsy are indispensableto the early diagnosis of this lung neoplasm...(AU)

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Background: Although mesenchymal neoplasms are prominent in horses due to the occurrence of sarcoids, other neoplasmsmay occur. Fibrosarcoma in horses is uncommon, notwithstanding, few studies have performed diagnostic techniques. Itis presumed, therefore, that other diagnostic methodologies should be explored. In this sense, fine needle aspiration cytology (FNAC) emerges as an effective, low-cost, and minimally invasive method to identify tumors in these animals. Theobjective of this study was to describe the use of FNAC in the diagnosis of oral fibrosarcoma in horses. Once fibrosarcomais an aggressive tumor, it is important to validate effective techniques for an early diagnosis.Case: A 10-year-old male Quarter Horse was treated, with a clinical complaint of increased volume in the right maxillaryregion. This tumor occupied about » of the hard palate area. Hyporexia, hypodipsia, mild dehydration, and weight losswere observed at clinical examination. Complementary examinations were requested, and an extensive radiolucent masswith an indication of bone involvement was observed on the radiograph. The hemogram revealed normocytic normochromicanemia, in addition to lymphopenia. In the serum biochemistry test, AST (aspartate aminotransferase) and creatinine wereslightly increased. FNAC showed a malignant mesenchymal neoplasm, possibly fibrosarcoma. Due to its clinical worsening and lack of response to supportive treatment, humanitarian euthanasia was performed. Finally, a histopathologicalexamination confirmed the oral fibrosarcoma suggested by FNAC.Discussion: The early diagnosis of neoplasms is important for its correct treatment, as well as the prognosis. In this way,the combined use of complementary tests helps in the resolution of the case. FNAC is still little used in the examinationroutine in horses. In the present report, this test demonstrated efficacy since it revealed mesenchymal cells compatible withfibroblasts...(AU)

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Background: Although mesenchymal neoplasms are prominent in horses due to the occurrence of sarcoids, other neoplasmsmay occur. Fibrosarcoma in horses is uncommon, notwithstanding, few studies have performed diagnostic techniques. Itis presumed, therefore, that other diagnostic methodologies should be explored. In this sense, fine needle aspiration cytology (FNAC) emerges as an effective, low-cost, and minimally invasive method to identify tumors in these animals. Theobjective of this study was to describe the use of FNAC in the diagnosis of oral fibrosarcoma in horses. Once fibrosarcomais an aggressive tumor, it is important to validate effective techniques for an early diagnosis.Case: A 10-year-old male Quarter Horse was treated, with a clinical complaint of increased volume in the right maxillaryregion. This tumor occupied about » of the hard palate area. Hyporexia, hypodipsia, mild dehydration, and weight losswere observed at clinical examination. Complementary examinations were requested, and an extensive radiolucent masswith an indication of bone involvement was observed on the radiograph. The hemogram revealed normocytic normochromicanemia, in addition to lymphopenia. In the serum biochemistry test, AST (aspartate aminotransferase) and creatinine wereslightly increased. FNAC showed a malignant mesenchymal neoplasm, possibly fibrosarcoma. Due to its clinical worsening and lack of response to supportive treatment, humanitarian euthanasia was performed. Finally, a histopathologicalexamination confirmed the oral fibrosarcoma suggested by FNAC.Discussion: The early diagnosis of neoplasms is important for its correct treatment, as well as the prognosis. In this way,the combined use of complementary tests helps in the resolution of the case. FNAC is still little used in the examinationroutine in horses. In the present report, this test demonstrated efficacy since it revealed mesenchymal cells compatible withfibroblasts...

Assuntos

RESUMO

Background: Due to their abundant vascular supply, the lungs are a usual metastatic site, with primary lung cancer presenting a low prevalence in dogs and cats. Among the primary pulmonary tumors afflicting dogs, lepidic carcinoma is the mostcommon and can be classified by site of onset. Lepidic predominant adenocarcinoma is characterized by the proliferationof neoplastic cells along the pulmonary alveoli and pre-existing alveolar structures. Few reports of this specific tumor werefound in the literature, so the objective of this study is to describe the clinical, pathological, and immunohistochemicalfindings of a dog with predominantly diffuse lepidic adenocarcinoma.Case: A 14-year-old, female, spayed, mixed-breed canine with a history of progressive weight loss, cough, respiratorydistress, and pain while eating was brought in for a consultation. A presumptive diagnosis of pneumonia was suggested.However, in spite of treatment, the dog died, and a necropsy was performed. Upon gross examination, the lungs were diffuselyenlarged, whitish, and stiffened with large and highly vascular nodules. Histopathological findings showed proliferation ofneoplastic cells along the vascular walls and within the bronchioalveolar structures, with moderate fibrovascular stroma.The growth patterns resembled the pre-existing alveolar structures, with papillary protrusions into the alveolar lumen.After immunohistochemical evaluation, the definitive diagnosis was diffuse lepidic predominant adenocarcinoma. Thistumor is uncommon and difficult to diagnose in the clinical veterinary routine, so it should be considered in the differentialdiagnosis of respiratory conditions in canines, especially in elderly animals with chronic clinical signs not responsive toantibiotic therapy. Complementary diagnostic examinations such as imaging, laboratory tests, and biopsy are indispensableto the early diagnosis of this lung neoplasm...

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RESUMO

Objetivou-se verificar a ocorrência e as causas de condenação de fígados de bovinos em um frigorífico na cidade de Condor, na região Noroeste do Estado do Rio Grande do Sul, sob regime de Inspeção Estadual, através da análise macroscópica e microscópica dos fígados condenados pelo SIE. Para isso, em um período de nove meses foram colhidas 196 amostras de lesões de fígado de bovinos. O material foi fotografado e fragmentos de fígado foram colhidos e fixados em formalina neutra a 10%, e processados rotineiramente para exame histopatológico. De acordo com o SIE, as razões para condenação foram: cirrose (26,54%), fasciolose (25,52%), peri-hepatite (15,81%), abscessos (14,79%), esteatose (10,71%), telangiectasia (3,06%) hidatidose (2,03%) e outras causas (1,54%). No exame microscópico, os fígados mostraram esteatose (26,54%), fasciolose (25,52%), abscessos (14,79%), sem alterações (13,77%), fibrose capsular (11,22%), telangiectasia (3,06%), peri-hepatite (3,06%), calcificação focal (1,02%) e hidatidose (1,02%). No presente estudo houve diferenças em alguns diagnósticos macroscópicos realizados pelos inspetores quando comparados com os diagnósticos microscópicos, demonstrando que há falta de aperfeiçoamento dos inspetores na linha de inspeção, corroborando com estudos já realizados.(AU)

The aim of this study is to verify the occurrence and causes of liver condemnation in a slaughter house in Condor, at the Northwest region of Rio Grande do Sul, under state inspection, through macroscopic and microscopic liver condemned by the SIE (State Inspection Service). During a period of nine month, were collected 196 samples of cattle injured liver. The material was pictured and liver fragments were collected and fixed in 10% neutral formalin and routinely processed for histopathological examination. According to the SIE, the reasons for judgment were: cirrhosis (26.54%), fascioliasis (25.52%), perihepatitis (15.81%), abscesses (14.79%), steatosis (10 71%), telangiectasia (3.06%) hydatid disease (2.03%) and other causes (1.54%). On microscopic examination, the livers showed steatosis (26.54%), fasciolosis (25.52%), abscesses (14.79%), unchanged (13.77%), capsular fibrosis (11.22%), telangiectasia (3.06%), perihepatitis (3.06%), focal calcification (1.02%) and hydatid disease (1.02%). In this study there were differences in some macroscopic diagnoses made by inspectors when compared to the microscopic diagnosis, showing that there is a lack of training by the inspectors in the inspection line, confirming previous studies.(AU)

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Objetivou-se verificar a ocorrência e as causas de condenação de fígados de bovinos em um frigorífico na cidade de Condor, na região Noroeste do Estado do Rio Grande do Sul, sob regime de Inspeção Estadual, através da análise macroscópica e microscópica dos fígados condenados pelo SIE. Para isso, em um período de nove meses foram colhidas 196 amostras de lesões de fígado de bovinos. O material foi fotografado e fragmentos de fígado foram colhidos e fixados em formalina neutra a 10%, e processados rotineiramente para exame histopatológico. De acordo com o SIE, as razões para condenação foram: cirrose (26,54%), fasciolose (25,52%), peri-hepatite (15,81%), abscessos (14,79%), esteatose (10,71%), telangiectasia (3,06%) hidatidose (2,03%) e outras causas (1,54%). No exame microscópico, os fígados mostraram esteatose (26,54%), fasciolose (25,52%), abscessos (14,79%), sem alterações (13,77%), fibrose capsular (11,22%), telangiectasia (3,06%), peri-hepatite (3,06%), calcificação focal (1,02%) e hidatidose (1,02%). No presente estudo houve diferenças em alguns diagnósticos macroscópicos realizados pelos inspetores quando comparados com os diagnósticos microscópicos, demonstrando que há falta de aperfeiçoamento dos inspetores na linha de inspeção, corroborando com estudos já realizados.

The aim of this study is to verify the occurrence and causes of liver condemnation in a slaughter house in Condor, at the Northwest region of Rio Grande do Sul, under state inspection, through macroscopic and microscopic liver condemned by the SIE (State Inspection Service). During a period of nine month, were collected 196 samples of cattle injured liver. The material was pictured and liver fragments were collected and fixed in 10% neutral formalin and routinely processed for histopathological examination. According to the SIE, the reasons for judgment were: cirrhosis (26.54%), fascioliasis (25.52%), perihepatitis (15.81%), abscesses (14.79%), steatosis (10 71%), telangiectasia (3.06%) hydatid disease (2.03%) and other causes (1.54%). On microscopic examination, the livers showed steatosis (26.54%), fasciolosis (25.52%), abscesses (14.79%), unchanged (13.77%), capsular fibrosis (11.22%), telangiectasia (3.06%), perihepatitis (3.06%), focal calcification (1.02%) and hydatid disease (1.02%). In this study there were differences in some macroscopic diagnoses made by inspectors when compared to the microscopic diagnosis, showing that there is a lack of training by the inspectors in the inspection line, confirming previous studies.

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RESUMO

Objetivou-se verificar a ocorrência e as causas de condenação de fígados de bovinos em um frigorífico na cidade de Condor, na região Noroeste do Estado do Rio Grande do Sul, sob regime de Inspeção Estadual, através da análise macroscópica e microscópica dos fígados condenados pelo SIE. Para isso, em um período de nove meses foram colhidas 196 amostras de lesões de fígado de bovinos. O material foi fotografado e fragmentos de fígado foram colhidos e fixados em formalina neutra a 10%, e processados rotineiramente para exame histopatológico. De acordo com o SIE, as razões para condenação foram: cirrose (26,54%), fasciolose (25,52%), peri-hepatite (15,81%), abscessos (14,79%), esteatose (10,71%), telangiectasia (3,06%) hidatidose (2,03%) e outras causas (1,54%). No exame microscópico, os fígados mostraram esteatose (26,54%), fasciolose (25,52%), abscessos (14,79%), sem alterações (13,77%), fibrose capsular (11,22%), telangiectasia (3,06%), peri-hepatite (3,06%), calcificação focal (1,02%) e hidatidose (1,02%). No presente estudo houve diferenças em alguns diagnósticos macroscópicos realizados pelos inspetores quando comparados com os diagnósticos microscópicos, demonstrando que há falta de aperfeiçoamento dos inspetores na linha de inspeção, corroborando com estudos já realizados.

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Background: Infectious canine hepatitis (ICH) is a systemic viral disease of dogs. It affects mainly unvaccinated dogs under the age of six months. Although clinical signs of ICH are not specific, the necropsy findings are sufficient to allow a presumptive diagnosis associated with epidemiology and clinical signs. Clinician should suspect the disease when two years-old dogs or younger present acute death with abdominal pain, neurological disorders and signs of bleeding. The objective of this study is to report an unusual case of ICH, describing the clinical and pathological findings in a geriatric dog with the disease. Case: A female Basset Hound dog, 9 year-old, was presented with intense vomiting and diarrhea in the last day. The animal was not vaccinated there was two years. The blood count revealed moderate leukocytosis by neutrophils and deviation to the left and to the right, and monocytosis, besides lymphopenia and eosinopenia. It was also possible to observe hyperproteinemia and plasma intensely jaundiced. The biochemical examination showed alterations in liver and kidney parameters. After three days of hospitalization, the patient was euthanized and submitted for necropsy. Macroscopic findings consisted of increased dark red liver, and fibrin strands in the capsular surface. There was a bloody fluid in the small intestine and stomach. Serous small intestine showed...(AU)

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Background: Infectious canine hepatitis (ICH) is a systemic viral disease of dogs. It affects mainly unvaccinated dogs under the age of six months. Although clinical signs of ICH are not specific, the necropsy findings are sufficient to allow a presumptive diagnosis associated with epidemiology and clinical signs. Clinician should suspect the disease when two years-old dogs or younger present acute death with abdominal pain, neurological disorders and signs of bleeding. The objective of this study is to report an unusual case of ICH, describing the clinical and pathological findings in a geriatric dog with the disease. Case: A female Basset Hound dog, 9 year-old, was presented with intense vomiting and diarrhea in the last day. The animal was not vaccinated there was two years. The blood count revealed moderate leukocytosis by neutrophils and deviation to the left and to the right, and monocytosis, besides lymphopenia and eosinopenia. It was also possible to observe hyperproteinemia and plasma intensely jaundiced. The biochemical examination showed alterations in liver and kidney parameters. After three days of hospitalization, the patient was euthanized and submitted for necropsy. Macroscopic findings consisted of increased dark red liver, and fibrin strands in the capsular surface. There was a bloody fluid in the small intestine and stomach. Serous small intestine showed...

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