RESUMO
Doze pacientes virchovianos portadores de leucoplasias foram avaliados imunologicamente visando determinar a participaçäo do sistema imune nesta manifestaçäo. As provas utilizadas näo demonstraram qualquer normalidade imunológica nestes pacientes de modo que, nossos resultados näo apoiam a idéia de envolvimento imune inespecífico na patogênese das leucoplasia na cavidade bucal
Assuntos
Adulto , Pessoa de Meia-Idade , Humanos , Masculino , Feminino , Hanseníase Virchowiana/imunologia , Leucoplasia Oral/imunologia , Imunidade Celular , Leucoplasia Oral/patologiaRESUMO
The authors verified histologically in 20 no dentates patients, the influence of complete dentures on the hard palate mucosa. The patients were divided in two groups: I. Patients that never used complete dentures; II. Patients that were using complete dentures when this research was realized. New prosthesis were made for each one of the 20 patients. Immediately before they received the new prosthesis and ninety days after this, biopsies were realized. The circunferencial pieces of the hard palate mucosa were fixed in formol 10% and coloured with Hematoxylin/Eosin and Mallory's Tricomic for histomorphologic analysis and measuring of the stratum corneum of the epithelium. It was made the statistical analysis and the results showed that: 1. In normal conditions, the utilization of the full dentures produces the reduce of the thickness of the stratum corneum. This was more observed in Group I. 2. The range difference of the thickness of the stratum corneum between the first and the second biopsies in the groups I and II (4.86 microns and 2.18 microns) were not statistically significant. 3. With the use of complete dentures the stratum corneum of the epithelium showed tendence to parakeratinization.