RESUMO
Topiramate is a sulfamate-substituted monosaccharide mainly used to treat epilepsy in children and adults and prophylaxis of migraine. This article describes a case of topiramate-induced acute transient myopia. The underlying mechanism and management is discussed. A 13-year-old female complained of sudden onset of blurred vision; 7 days prior to this she had commenced topiramate therapy for migraine prophylaxis. Visual acuity was reduced in both eyes. Examination revealed myopic refractive changes which resolved quickly following discontinuation of the drug. An MRI showed uveoscleral and subcutaneous cellular tissue abnormalities in the T1 contrasted images.
Assuntos
Frutose/análogos & derivados , Miopia/induzido quimicamente , Miopia/diagnóstico , Fármacos Neuroprotetores/efeitos adversos , Adolescente , Meios de Contraste , Feminino , Frutose/efeitos adversos , Cefaleia/tratamento farmacológico , Humanos , Imageamento por Ressonância Magnética , TopiramatoAssuntos
Blefaroptose/diagnóstico , Transtornos de Enxaqueca/diagnóstico , Doenças do Nervo Oculomotor/diagnóstico , Oftalmoplegia/diagnóstico , Adolescente , Blefaroptose/complicações , Blefaroptose/prevenção & controle , Diagnóstico Diferencial , Feminino , Humanos , Transtornos de Enxaqueca/complicações , Doenças do Nervo Oculomotor/complicações , Doenças do Nervo Oculomotor/prevenção & controle , Oftalmoplegia/complicações , Prevenção SecundáriaRESUMO
Anabolic-androgenic steroid (AAS) abuse increased in recent years, and it is associated with numerous adverse effects. Few reports on ischemic stroke related to anabolic steroid abuse have been published. We report a case of a 26-year-old male amateur athlete who suffered a posterior territory ischemic stroke. No abnormalities were found in angiography and echocardiography studies, neither in hemostatic profile. His only significant risk factor was nonmedical use of stanozolol, an anabolic steroid. Anabolic steroids are capable of increasing vascular tone, arterial tension, and platelet aggregation; therefore, they are prone to produce atherothrombotic phenomena. Because of young people's widespread use of anabolic steroids, physicians should be aware of this kind of complication.