RESUMO
A discussion is carried out about the experiences with the application of rimantadine and amantadine to patients with influenza. The basic general results consisted in the fact that 2 of the 74 patients treated had a high cure percent (> 68.0%) within the first 72 hours after using the drug. No new diseased were found among the 40 contacts to whom chemoprophylaxis was applied. There were only 3.9% adverse reactions among the total number of people treated with amantadine.
Assuntos
Amantadina/uso terapêutico , Antivirais/uso terapêutico , Influenza Humana/tratamento farmacológico , Rimantadina/uso terapêutico , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Instituição de Longa Permanência para Idosos , Hospitalização , Humanos , Pessoa de Meia-IdadeRESUMO
A study of an outbreak of acute respiratory disease was done at the "Carlos Font Pupo" Old People's Home. Las Tunas Province, where 30 diseased old individuals were detected; grippe was diagnosed to two of them. General attack rate was 8.6%. Curative treatment with amantadine was administered to 29 old patients and chemoprophylaxis to 26, for a total of 55 old individuals treated. The evolution of the patients was satisfactory and none new case was observed. Diarrhea was the only one secondary reaction observed in a patient under chemoprophylactic treatment. The need to carry on performing similar studies is pointed out.