RESUMO

Dunalia spinosa, a plant used in folk medicine for toothaches, breathing problems and cleansing wounds, was found active as antimicrobial and antioxidant. A new (E)-aurone rutinoside (dunaurone) has been isolated from the aerial parts of the plant, and its structure was determined by spectroscopic means. Lupeol, beta-sitosterol, scopoletin, quercetin and withaferin A were also found. All the extracts exhibited strong antimicrobial activity while dunaurone showed only weak antimicrobial inhibition against Klebsiella pneumoniae; in addition it presented a significant free radical scavenging activity.

Assuntos

Antibacterianos/farmacologia , Extratos Vegetais/farmacologia , Solanaceae/química , Antibacterianos/química , Espectrometria de Massas , Testes de Sensibilidade Microbiana , Extratos Vegetais/química , Espectrofotometria Ultravioleta , Superóxidos/metabolismo , Xantina Oxidase/metabolismo