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SARS-CoV-2's rapid global spread caused the declaration of COVID-19 as a pandemic in March 2020. Alongside humans, domestic dogs and cats are also susceptible to infection. However, limited reports on pet infections in Chile prompted a comprehensive study to address this knowledge gap. Between March 2021 and March 2023, the study assessed 65 pets (26 dogs and 39 cats) from 33 COVID-19+ households alongside 700 nasal swabs from animals in households with unknown COVID-19 status. Using RT-PCR, nasal, fecal, and environmental samples were analyzed for the virus. In COVID-19+ households, 6.06% tested positive for SARS-CoV-2, belonging to 3 dogs, indicating human-to-pet transmission. Pets from households with unknown COVID-19 status tested negative for the virus. We obtained 2 SARS-CoV-2 genomes from animals, that belonged to Omicron BA.4.1 variant, marking the first report of pets infected with this lineage globally. Phylogenetic analysis showed these sequences clustered with human sequences collected in Chile during the same period when the BA.4.1 variant was prevalent in the country. The prevalence of SARS-CoV-2 in Chilean pets was relatively low, likely due to the country's high human vaccination rate. Our study highlights the importance of upholding and strengthening human vaccination strategies to mitigate the risk of interspecies transmission. It underscores the critical role of the One Health approach in addressing emerging zoonotic diseases, calling for further research on infection dynamics and risk factors for a comprehensive understanding.

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Antecedentes. En 2003 se reportó incidencia de 762 casos de neumoconiosis y 3686 casos de enfermedad respiratoria crónica en Colombia.Objetivo. Evaluar la utilidad de las técnicas de espirometría y oximetría para determinar la prevalencia de disfuncionalidad respiratoria en trabajadores de minas de carbón de Paipa–Boyacá y establecer posibles factores asociados, como edad y tiempo de exposición, para proponer medidas preventivas de salud ocupacional.Material y métodos. Estudio de corte transversal, observacional, analítico. Mediante instrumento previamente diseñado se encuestó a 410, trabajadores de las minas de carbón. Se evaluaron aspectos generales del trabajo, antecedentes de salud y parámetros de función respiratoria por espirometría y oximetría.Resultados. Grupo de sujetos jóvenes: promedio de edad 35,07 años (SD=11,75). Promedio de exposición 12,8 años (SD=11,8). Alta prevalencia de síntomas respiratorios: tos (42,7 por ciento); expectoración (31,46 por ciento); disnea (48,8 por ciento); dolor torácico (19,75 por ciento). En 26,1 por ciento alteración funcional respiratoria y en 3,99 por ciento, hipoxemia. Tiempo de exposición superior a cinco años se asoció con alteración respiratoria (RP=1,75) y con hipoxemia (RP= 9,30). Igualmente edad superior a 40 años se asoció con alteración espirométrica (RP=1,91) e hipoxemia (RP=3,07). Conclusiones. Actividad de alto riesgo. Altas prevalencias de sintomatología sugestiva de neumoconiosis y enfermedad pulmonar crónica en progreso. Se encuentran elevadas prevalencia de anormalidad del patrón respiratorio y de hipoxemia, lo cual sugiere que estas estimaciones podrían ser predictores del desarrollo de enfermedad pulmonar crónica de origen laboral.

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UNLABELLED: Obesity has increased worldwide affecting people of all ages and accounting for a severe public health problem. There exist several treatment options for obesity: dietary, pharmacological, physical exercising, psychotherapy, and surgical. Placement of the so-called intragastric ballonn, a silicone device similar to a 600-mL sphere, has been proposed, indicated for patients with a body mass index higher than 30 kg/m(2). OBJECTIVE: To assess the effect of the intragastric balloon as an alternative method for weight loosing in obese patients. METHODOLOGY: Longitudinal, experimental, descriptive, and exploring study. The sample includes 40 obese patients. Anthropometrical measurements including weight, height, abdominal circumference, tricipital and subscapular folds were done; the body mass index (BMI), muscle surface area and fat a surface area were calculated at baseline, first, third and sixth months after balloon placement. RESULTS: The sample comprised 31 women (77.5%) y 9 men (22.5%). The mean age for women was 35.87 years, and for men 44.67 years. At the end of the study, there was a total mean weight reduction of 18.25 kg, BMI 5.95 kg/m(2), abdominal circumference 13.53 cm, and arm circumference 4.14 cm, in both genders; the decrease in anthropometrical measurements was higher in men than women. CONCLUSIONS: The intragastric balloon showed to be an effective method for weight loosing in obese patients, with better outcomes in men than women.

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A patient with episodes of palpitation in whom the electrocardiogram showed a right bundle branch (RBBB) configuration and right axis deviation underwent electrophysiologic study and radiofrequency ablation. Left ventricular endocardial mapping during ventricular tachycardia (VT) identified the earliest ventricular activation in the anterolateral wall of the left ventricle. The fused Purkinje potential was recorded at that site, and preceded the QRS complex by 47 mseg, with pace mapping showing an optimal match between the paced rhythm and the clinical VT. The stimulus to QRS time was equal to the Purkinje potential-QRS time. Several radiofrequency lesions were applied in this region, one of them resulted with termination of the tachycardia. Following delivery of this lesion the ventricular tachycardia couldn't be induced either at baseline or during isoproterenol infusion. During VT, atrial fibrillation and atrial flutter were observed, cardioversion was performed reverting to sinus rhythm.

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