Assuntos
Nível de Saúde , Transplante de Rim , Doadores Vivos , Biomarcadores/sangue , Pressão Sanguínea/fisiologia , Creatinina/sangue , Feminino , Seguimentos , Humanos , Hipertensão/etiologia , Transplante de Rim/psicologia , Doadores Vivos/psicologia , Masculino , Pessoa de Meia-Idade , Porto RicoAssuntos
Transplante de Rim , Adulto , Cadáver , Criança , Sobrevivência de Enxerto , Humanos , Terapia de Imunossupressão , Transplante de Rim/efeitos adversos , Transplante de Rim/legislação & jurisprudência , Transplante de Rim/estatística & dados numéricos , Doadores Vivos , Morbidade , Porto Rico , Doadores de Tecidos , Obtenção de Tecidos e Órgãos/legislação & jurisprudênciaAssuntos
Emoções , Transplante de Rim , Doadores Vivos/psicologia , Adulto , Cadáver , Família , Feminino , Seguimentos , Sobrevivência de Enxerto , Humanos , Incidência , Relações Interpessoais , Falência Renal Crônica/epidemiologia , Falência Renal Crônica/cirurgia , Transplante de Rim/mortalidade , Transplante de Rim/fisiologia , Doadores Vivos/provisão & distribuição , Masculino , Pessoa de Meia-Idade , Porto Rico/epidemiologia , Cônjuges , Doadores de TecidosRESUMO
A total of 103 kidney transplantations from living-related donors were performed in the Puerto Rico Kidney Transplant Program between January 1977 and June 1984. The majority of these patients were male, 76% were between 21 and 50 years of age, 33% were indigent, and 38% were either black or of mixed race. Rigid exclusion criteria were established in the selection of kidney donors. All donor operations were at least 2-antigen-compatible. Surgical technique and posttransplant management were standard, except that in 1980 the immunosuppressive policy was changed as follows: posttransplant prednisone was very rapidly tapered to 20 mg/day at two weeks after transplantation and antilymphocyte globulin was used to treat all rejections. The overall 3-year patient survival for the 7 1/2 years is 91.6%, but after 1980 it increased to 98% perhaps a reflection of the changes in immunosuppressive policy. Eight of ten deaths were due to sepsis, most of them related to rejection treatment. The 3-year kidney survival was 77%. All kidney losses were due to rejection. A low incidence of urological complications is reported. There were no technical losses. A relatively low incidence of cancer is reported. Cutaneous mycosis is highly prevalent in our patients, but systemic fungi are virtually absent.