RESUMO
Osteosarcoma (OS) is the most common type of bone cancer, especially in young. Telangiectatic osteosarcoma (TO) is a rare variant of OS, and hence, its occurrence, presentation, and prognosis are poorly understood. A 4-year-old female rhesus monkey presenting lameness and swelling was examined for a mass on the right humerus. Radiography revealed fracture and disorganized structure of bone tissue. Histopathological examination revealed malignant neoplasm composed of anaplastic osteoblasts, which invaded the bone marrow and surrounded blood-filled cysts in the epiphysis and diaphysis forming septa. Cytogenetic analysis showed aneuploid cells, supernumerary AgNORs, and a marker fragment. The neoplasm was diagnosed as TO. To our knowledge, the occurrence of TO and its cytogenetic analysis were reported for the first time in non-human primates.
Assuntos
Neoplasias Ósseas/veterinária , Macaca mulatta , Doenças dos Macacos/diagnóstico por imagem , Osteossarcoma/veterinária , Telangiectasia/veterinária , Animais , Neoplasias Ósseas/diagnóstico por imagem , Análise Citogenética/veterinária , Feminino , Osteossarcoma/diagnóstico por imagem , Radiografia/veterinária , Telangiectasia/diagnóstico por imagemRESUMO
Saimiri (squirrel monkey) is a neotropical primate of the Simian genus that has been bred in captivity for the development of research into human and animal health. They have been widely used in studies in ophthalmology, toxicology, pharmacology, psychiatry, neuroscience, vaccines and drug tests (such as malaria and measles agents), as well as effects on interactive behavior and cognition of Creutzfeldt-Jakob disease in man. The main concern of non-human primate (NHP) research centers is focused on the establishment of self-sustaining breeding colonies providing good quality research animals. Maternal rejection, dystocia and pneumonia are the main causes of newborn deaths in these species. Therefore, in order to ensure the survival of these valuable animals, the Laboratory Animals Breeding Center of the Oswaldo Cruz Foundation (CECAL)/Fiocruz, Rio de Janeiro, Brazil, has developed a protocol for the nursery rearing of these infants.
Assuntos
Criação de Animais Domésticos/métodos , Saimiri/fisiologia , Animais , BrasilRESUMO
Although congenital thumb absence has been reported frequently in humans, their occurrence in macaques is rare. We observed three cases of spontaneous thumb defects in captive female rhesus monkeys. One animal exhibited bilateral absence and two other presented unilateral thumb absence, all with metacarpal integrity. This report presents the clinical, radiological, and genealogical details as well as possible etiologies in an attempt to draw a parallel with humans and other primate species.
Assuntos
Macaca mulatta/anormalidades , Polegar/anormalidades , Animais , Feminino , Radiografia , Polegar/diagnóstico por imagemRESUMO
Data on reproductive activity of fossorial species are limited because the specimens are difficult to be observed and captured. Here in, we present the reproductive cycle of female Atractus pantostictus, a fossorial neotropical species, and the sexual maturity of males and females in south-eastern Brazil. The female reproductive cycle of A. pantostictus is seasonal, with vitellogenic follicles being found from September to April and eggs in November, February, March and April with the number varying between two and four. Spermatozoa were found in the lumen of the glandular and non-glandular uterus in females collected during the rainy season. Sperm storage tubules were found in the posterior infundibulum of the females, where the storage of sperm occurs for a short time. The storage may occur because mating and ovulation are dissociated.