RESUMO

A model of multiple lung metastases in BDIX rats is under study at CNEA (Argentina) to evaluate the feasibility of BNCT for multiple, non-surgically resectable lung metastases. A practical shielding device that comfortably houses a rat, allowing delivery of a therapeutic, uniform dose in lungs while protecting the body from the neutron beam is presented. Based on the final design obtained by numerical simulations, the shield was constructed, experimentally characterized and recently used in the first in vivo experiment at RA-3.

Assuntos

Terapia por Captura de Nêutron de Boro/instrumentação , Neoplasias Pulmonares/radioterapia , Neoplasias Pulmonares/secundário , Proteção Radiológica/instrumentação , Planejamento da Radioterapia Assistida por Computador/métodos , Animais , Desenho Assistido por Computador , Desenho de Equipamento , Análise de Falha de Equipamento , Dosagem Radioterapêutica , Ratos