RESUMO
INTRODUCTION: Visceral adipose tissue (VAT) is related to cardiometabolic risk. Estimating it using the visceral adiposity index (VAI) could identify this risk in the Brazilian Air Force (BAF) aviator population. The aim here is to verify the predictive capacity of the VAI for identifying visceral fat areas compared to traditional obesity indicators in BAF pilots. MATERIALS AND METHODS: Forty male BAF pilots were recruited. The study was conducted in two stages: the first applied a structured questionnaire to characterize the sample and identify sedentary behavior and the second obtained nutritional, anthropometric, and body composition data, carrying out biochemical and magnetic resonance imaging tests and investigating physical activity level in this stage. The comparison of the predictive capacity of the VAI with that of other adiposity indicators (body mass index [BMI], waist circumference, waist-height ratio, waist-hip ratio, and neck circumference) for detecting increased VAT and the determination of the optimal cutoff points for the different adiposity indicators were carried out using receiving operating characteristic (ROC) curves. An association was verified between the adiposity indicators and excess visceral fat using Poisson regression analysis with robust variance. RESULTS: The VAI presented a better predictive capacity for VAT (area under the ROC curve = 0.941), while the BMI did not present diagnostic accuracy (95% CI < 0.5). The strength of the association with high visceral fat was also greater for the VAI than for the other indicators evaluated. CONCLUSIONS: The VAI was shown to be a better predictor of excess VAT in relation to the other indicators studied. As it is a more easy-access and lower-cost technique than resonance, it enables greater applicability in tracing and monitoring the visceral obesity of a large contingent of military personnel.
RESUMO
BACKGROUND AND AIM: Fat distribution may have prognostic value in the evaluation of non-alcoholic fatty liver disease. This study was conducted to evaluate associations of magnetic resonance imaging-measured abdominal fat areas with steatosis, steatohepatitis, and fibrosis, assessed histopathologically, in patients with type 2 diabetes. METHODS: This prospective study included 66 patients with type 2 diabetes (12 males, 54 females, age 26-68 years), without chronic liver disease of other causes. Axial dual-echo magnetic resonance images were acquired. Visceral, subcutaneous, and preperitoneal fat areas were measured using Osirix software. Liver biopsy specimens were obtained from all patients and examined histopathologically to evaluate steatosis, steatohepatitis, and fibrosis. Linear (for steatosis) and logistic (for steatohepatitis and fibrosis) regression models were fitted for the outcomes. R2 was used as a measure of how much model variance the predictors explained and to compare different predictors of the same outcome. RESULTS: Visceral and preperitoneal fat areas correlated well with histopathologically determined liver steatosis grade (both P = 0.004) and liver fibrosis (P = 0.008 and P = 0.037, respectively). All fat areas correlated well with steatohepatitis (P ≤ 0.002). Preperitoneal and visceral fat areas were the best predictors of steatohepatitis (R2 = 0.379) and fibrosis (R2 = 0.181), respectively. CONCLUSIONS: Visceral fat area was the best predictor of fibrosis in patients with type 2 diabetes. Preperitoneal fat area was the best predictor of steatohepatitis and is a potential new non-invasive marker for use in the screening of these patients to detect more aggressive forms of non-alcoholic fatty liver disease.
Assuntos
Diabetes Mellitus Tipo 2/complicações , Gordura Intra-Abdominal , Hepatopatia Gordurosa não Alcoólica/etiologia , Biomarcadores , Feminino , Humanos , Gordura Intra-Abdominal/diagnóstico por imagem , Gordura Intra-Abdominal/patologia , Cirrose Hepática/diagnóstico por imagem , Imageamento por Ressonância Magnética , Masculino , Pessoa de Meia-Idade , Hepatopatia Gordurosa não Alcoólica/diagnóstico por imagem , Prognóstico , RiscoRESUMO
A Síndrome de Budd-chiari é caracterizada pela oclusão das veias supra-hepáticas e apresenta inúmeras causas, mas nenhuma delas é identificável em cerca de 60-70% dos pacientes. O diagnóstico é realizado pela suspeita clínica e confirmado por exames complementares, sendo a ultrassonografia com Doppler a mais sensível (85%). A terapia varia desde medicamentos, cirurgias como anastomoses portossistêmicos e transplante hepático até métodos menos invasivos como derivação intra-hepática portossistêmica transjugular (TIPS) e angioplastia. O objetivo desse trabalho é apresentar um paciente portador da SBC submetido à angioplastia transjugular da veia supra-hepática, utilizando via anterógrada (punção através da veia cava inferior trans-hepática, atingindo a veia supra-hepática e recanalizando anterogradamente a veia supra-hepática).
The Budd-chiari syndrome is characterized by occlusion of the supra-hepatic veins and has any causes, but none of them are identifiable by about 60-70% of patients. The diagnosis is made by clinical suspicion and confirmed by additional tests, and the Doppler ultrasound with the most sensitive (85%). The therapy varies from medications, surgeries such as liver transplantation and anastomosis portossistêmicos even less invasive methods like bypass intra-hepatic portosystemic transjugular (TIPS) and angioplasty. The aim of this article is to present a patient of SBC submitted to angioplasty transjugular the above hepatic vein using antegrade route (puncture through the inferior vena cava reaching the above-hepatic vein and the vein recanalizando anterograde above-liver).
Assuntos
Humanos , Masculino , Pessoa de Meia-Idade , Angioplastia , Derivação Portossistêmica Transjugular Intra-Hepática , Síndrome de Budd-Chiari , Síndrome de Budd-Chiari/diagnóstico por imagemRESUMO
Pileflebite é uma complicação incomum das infecções intra-abdominais e está associada à alta mortalidade. A patogenia ainda não está esclarecida. O diagnóstico permanece difícil e frequentemente é tardio, uma vez que a clínica é inespecífica e é necessário um elevado grau de suspeição. Na maioria dos casos, o prognóstico é favorável. O fator mais importante é a precocidade no diagnóstico e a imediata antibioticoterapia específica. Relatamos um caso de um paciente com diagnóstico de pileflebite mesentérica secundária à diverticulite colônica.
Pylephlebitis is a uncommon complications of intraabdominalsuppuration and associated with high mortality. The pathogenic is not clear and diagnosis remains delay because of its nonspecific symptoms and is necessary high clinical suspicion. In the major of cases the prognostic is favorable. The most important determinants for the prognosis is earlydiagnosis and adequate medical. We report a case of patient with diagnosis of mesenteric Pylephlebitis secondary a colonic diverticulitis.