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1.
Res Sq ; 2023 Aug 10.
Artigo em Inglês | MEDLINE | ID: mdl-37609191

RESUMO

Background: The use of heuristics in clinical decision-making processes increases in contexts of high uncertainty, such as those in Intensive Care Units (ICU. Given the impossibility of empirically studying their impact on real-world conditions, clinical vignettes were developed with the goal of identifying the use of heuristics in the care of critically ill patients during the COVID-19 pandemic in different clinical contexts. Methodology: Vignettes were designed by critical care physicians in Spain to assess the use of representativeness, availability, and status quo heuristics in the care of critically ill patients during the COVID-19 pandemic. The construct, internal and external validity of the vignettes designed in Spain, the United States and Chile were evaluated. A questionnaire was piloted with the vignettes being validated in the three aforementioned countries through a computer application built for this purpose. Results: 16 study vignettes grouped into 5 models were created: each model included between 2 and 4 vignettes. The vignettes designed were closed-response vignettes with 2-3 possible alternatives. The vignettes, initially developed in Spain in Spanish, were translated to English and adapted to the Spanish used in Chile. The clinical content of the vignettes was not modified during the translation process. Conclusions: The vignettes allow for the study of the use of heuristics in critical care clinical decision making in the context of the COVID-19 pandemic. The piloting and validation process used can serve as a model for similar multinational studies exploring clinical decision making.

2.
Rev. colomb. anestesiol ; 50(4): e301, Oct.-Dec. 2022. tab, graf
Artigo em Inglês | LILACS | ID: biblio-1407951

RESUMO

Abstract The deadly triad concept represented a dogma in the definition of poor outcomes and death associated with major bleeding in trauma. This model of end-stage disease was then rapidly transferred to other major bleeding scenarios. However, and notwithstanding the fact that it represented a severe scenario, the original triad fails to establish a sequence, which would be relevant when defining the objectives during the initial treatment of severe bleeding. Likewise, this model admits only one scenario where all the conditions shall co-exist, knowing that each one of them contributes with a different risk burden. Based on a structured review, we propose a pentad model that includes a natural pattern of events occurring with hypoxemia as the main trigger for the development of hypocalcemia, hyperglycemia, acidosis and hypothermia, as surrogates of multi-organ impairment. This severity model of major bleeding considers coagulopathy as a result of the failure to restore the initial components of damage.


Resumen El concepto de la tríada mortal significó un dogma en la definición de malos desenlaces y muerte asociados al sangrado mayor en trauma. Este modelo de afectación terminal fue luego rápidamente trasladado a otros escenarios de sangrado mayor. Sin embargo y a pesar de significar un escenario de gravedad, la tríada original falla en adjudicar una secuencialidad, lo cual sería importante a la hora de definir los objetivos durante el tratamiento inicial de la hemorragia grave. De igual forma, solo admite un único escenario en donde deben coexistir todas las condiciones, cuando se sabe que cada una atribuye una carga diferencial de riesgo. A partir de una revisión estructurada proponemos un modelo de pentada que incluye un patrón natural de eventos que se implantan sobre la hipoxemia como principal detonante para el desarrollo de hipocalcemia, hiperglucemia, acidosis e hipotermia como representantes del deterioro en múltiples sistemas. Este modelo de gravedad del sangrado mayor culmina con la coagulopatía como resultante de la falla en la resolución de los demás componentes previos.

3.
Rev. colomb. anestesiol ; 48(4): e202, Oct.-Dec. 2020. tab, graf
Artigo em Inglês | LILACS, COLNAL | ID: biblio-1144313

RESUMO

Abstract Introduction: Surgical site infection (SSI) is among the most common healthcare-related infections. Given their greater morbidity and surgical complexity, patients undergoing major surgery are exposed to a high risk of SSI. Objective: To determine the incidence of SSI in adult patients undergoing major elective non-cardiac surgery, and to identify risk factors associated with its occurrence within the first 30 days after surgery. Methods: An analytical study was designed on the basis of a prospective institutional registry. Clinical and laboratory variables associated with perioperative management were recorded. An active search was conducted in order to find SSI episodes, renal failure and multiple organ dysfunction during the first 30 days after surgery. Adjusted logistic regression was done to identify potential associations between risk factors and the development of SSI. Results: Overall, 1501 patients were included. The incidence of SSI during the first 30 days after surgery was 6.72% (95% CI 5.57-8.11). ASA III, abdominal surgery and longer procedures were more frequent in the SSI group. Association with the occurrence of SSI was documented for preoperative hemoglobin levels (adjusted OR 0.79 [95% CI 0.72-0.88], p = 0.04), intraoperative transfusion (adjusted OR 2,47 [95% CI 1.16-5.27], p = 0.02) and major blood loss (adjusted OR 3.80 [95% CI 1.63-8.88], p = 0.04). Conclusion: Preoperative hemoglobin level, intraoperative transfusion and major bleeding are independent risk factors associated with the occurrence of SSI in adult patients undergoing major elective non-cardiac surgery.


Resumen Introducción: La infección del sitio operatorio (ISO) ocupa los primeros lugares entre las infecciones asociadas a la atención en salud. Con una mayor morbilidad y complejidad quirúrgica, los pacientes de cirugía mayor están expuestos a un alto riesgo de ISO. Objetivo: Determinar la incidencia de ISO en pacientes adultos sometidos a cirugía mayor electiva no cardiaca e identificar factores de riesgo relacionados con su aparición durante los primeros 30 días postoperatorios. Métodos: Se diseñó un estudio analítico a partir de un registro institucional prospectivo. Se registraron variables clínicas y de laboratorio relacionadas con el manejo perioperatorio. Se realizó una búsqueda activa de episodios de ISO, sepsis, falla renal y disfunción multiorgánica durante los primeros 30 días postoperatorios. Las potenciales asociaciones entre factores de riesgo y el desarrollo de ISO fueron identificadas mediante regresión logística ajustada. Resultados: Se incluyeron 1.501 pacientes. La incidencia de ISO durante los 30 días postoperatorios fue de 6,72 % [IC 95 % 5,57-8,11). El estado ASA III, la cirugía abdominal y los procedimientos de duración prolongada fueron más frecuentes en el grupo ISO. Se documentó asociación con la ocurrencia de ISO para los niveles de hemoglobina preoperatoria (OR ajustado 0,79 [IC 95 % 0,72-0,88], p = 0,04), transfusión intraoperatoria (OR ajustado 2,47 [IC 95 % 1,16-5,27], p = 0,02) y sangrado mayor intraoperatorio (OR ajustado 3,80 [IC 95 % 1,63-8,88], p = 0,04). Conclusiones: El nivel de hemoglobina preoperatoria, la transfusión intraoperatoria y el sangrado mayor son factores de riesgo asociados de forma independiente a la ocurrencia de ISO en pacientes adultos llevados a cirugía mayor electiva no cardiaca.


Assuntos
Humanos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Infecção da Ferida Cirúrgica , Hemorragia , Sangue , Fatores de Risco , Sepse , Infecções , Anemia
4.
Rev. colomb. anestesiol ; 45(1): 39-45, Jan.-June 2017. ilus, tab
Artigo em Inglês | LILACS, COLNAL | ID: biblio-900330

RESUMO

Abstract Introduction: To achieve minimal physiological goals in patients with penetrating thoracoabdominal trauma (TAPT) is essential to ensure adequate outcomes. Objectives: To determine the success in meting basic standards at the end of damage control surgery in subjects with TAPT: (1) Monitoring and prevention of hyperfibrinolysis; (2) central temperature >35 °C; (3) platelet count >50,000/mm³ and serum fibrinogen >150mg/dl; (4) hemoglobin levels >7.5 mg/dl and base deficit <6. Methods: Subjects >18 years old undergoing damage control surgery as a result of TAPT were prospectively collected at a referral center between October Oct-2012 and Dec-2014. Comparisons were done according to the Injury Severity Score (ISS) with a severity value indicator of >25. A p < 0.05 value was considered significant. Results:106 subjects with TAPT were enrolled. Administration of tranexamic acid was only reported in 52.7% of the patients, particularly in the group with low severity scores [Group ISS < 25 36.3% vs. group ISS > 25 65.8%. OR 3.37 (95% CI 1.2-9.85); p = 0.01]. Although the temperature was reported in 91% of the cases, only 66.2-71.4% reached the recommended goal. Serum fibrinogen was measured in 59.5% of the cases and only 52% met the recommended level. The base deficit values of <6 at the end of surgery were only accomplished in 40-43.8% of the subjects, with a significantly lower probability in the more severe patients [53% vs. 35.9%. OR 2.04 (95% CI 1.2-6.02); p = 0.042]. Conclusions: A considerable proportion of patients with TAPT does not meet the current recommendations at the end of damage control surgery.


Introducción: El logro de metas fisiológicas mínimas en pacientes con trauma toracoabdominal penetrante (TTAP) es fundamental para garantizar adecuados desenlaces. Objetivos: Determinar el éxito en el logro de estándares básicos al final de la cirugía de control de daños en sujetos con TTAP: 1.Monitorización y prevención de hiperfibrinolisis; 2.Temperatura central > 35 °C; 3.Niveles plaquetarios>50.000/mm3 y de fibrinógeno sérico > 150 mg/dl; 4.Niveles de hemoglobina > 7.5 mg/dl y déficit de base < 6. Métodos: Se recolectaron prospectivamente sujetos > 18 años llevados a cirugía de control de daños por TTAP en un centro de remisión entre Oct-2012 y Dic-2014. Las comparaciones se realizaron según el Injury severity score (ISS) teniendo como indicador de severidad un valor >25. Se consideró significativo un valor de p < 0.05. Resultados: Se registraron 106 sujetos con TTAP. La aplicación de ácido tranexámico solo se reportó en 52.7% de los pacientes, especialmente en el grupo con puntajes de severidad bajos [Grupo ISS<25 36.3% vs. grupo ISS > 25 65.8%. OR 3.37 (IC95% 1.2-9.85); p = 0.01]. A pesar de que la temperatura fue reportada en 91% de los casos, solo 66.2-71.4% alcanzaron la meta recomendada. El fibrinógeno sérico fue valorado en 59.5% de los sujetos y solo 52% alcanzaron la recomendación. Valores de déficit de base < 6 Al final de cirugía solo se lograron en 40-43.8% de los sujetos, con una probabilidad significativamente menor en los sujetos más graves [53% vs. 35.9%. OR 2.04 (IC95% 1.2-6.02); p = 0.042]. Conclusiones: Una proporción considerable de pacientes con TTAP no logran las recomendaciones actuales al final de la cirugía de control de daños.


Assuntos
Humanos
5.
Rev. méd. Chile ; 143(12): 1546-1551, dic. 2015. graf, tab
Artigo em Espanhol | LILACS | ID: lil-774440

RESUMO

Background: The causes of acute decompensations of patients with systemic autoimmune diseases are not well known. Aim: To describe the causes for consultation in an emergency room of patients with systemic autoimmune diseases. Material and Methods: Review of medical records of patients with systemic autoimmune diseases, aged over 14 years, consulting in an emergency room of a general hospital during three months. Results: In the study period, 166 patients with systemic autoimmune diseases consulted in the emergency room, of a total of 18,153 consultations (0.9%). Patients with rheumatoid arthritis were those that consulted with higher frequency (37%) followed by patients with systemic lupus erythematosus (21%). The most common causes for consultation were cardiovascular diseases in 25%, followed by digestive disorders in 15%. The most common diagnosis was chest pain with suspected ischemic heart disease in 36%. No differences in cardiovascular risk factors were observed between those patients consulting for cardiovascular diseases and those consulting for other causes. Conclusions: The most common cause of consultation in the emergency room of patients with systemic autoimmune diseases is cardiovascular.


Assuntos
Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Adulto Jovem , Doenças Autoimunes/terapia , Serviço Hospitalar de Emergência/estatística & dados numéricos , Doenças Autoimunes/classificação , Chile , Estudos Retrospectivos , Fatores de Risco , Centros de Atenção Terciária
6.
Arch. med. interna (Montevideo) ; 37(3): 158-162, nov. 2015.
Artigo em Espanhol | LILACS | ID: lil-770765

RESUMO

Resumen: Los traumatismos craneoencefálicos (TCE) constituyen un motivo de consulta frecuente en cualquier Servicio de Urgencias. Estados Unidos reporta hasta 1,7 millones de afectados en un año. En España la cifra, solo de TCE leve, se estima en 92000 por año. Los varones, sobre todo después de 65 años, constituyen el grupo más afectado y la caída desde su altura el mecanismo más frecuente. La asociación con tratamiento anticoagulante oral (TAO), agrega mayor complejidad a su manejo y constituye un tema en revisión constante. La necesidad de revertir la anticoagulación, los métodos para lograrlo, la indicación de un segundo control tomográfico en los pacientes con TCE leve-moderado, los algoritmos que orienten y organicen mejor las posibles conductas a seguir, continúan siendo aspectos en revisión. Una adecuada valoración inicial, control TC solo ante deterioro neurológico, y reversión de anticoagulación con complejo protrombínico permiten un manejo eficaz.


Abstract: Traumatic brain injury (TBI) is a frequent reason of consultation in any Emergency Room. The United States report up to 1.7 million affected individuals persons. In Spain, the figure corresponding only to mild TBI is estimated at 92,000 patients per year. Males, specially after age 65, are the most affected group and the most frequent injury mechanism is a a all from their height. The association with oral anticoagulant therapy (OAT) increases the complexity of its managament and is an issue under permanent review. The need to reverse anticoagulation, the methods to achieve it, the prescription of a second CT control in patients with mild to moderate TBI, the algorithms to better guide and organize the possible courses of action are still issues under review. An adequate initial assessment, a CT control only in case of neurological damage and reversion of anticoagulation with prothrombin complex allow an effective management.

7.
Rev Med Chil ; 143(12): 1546-51, 2015 Dec.
Artigo em Espanhol | MEDLINE | ID: mdl-26928616

RESUMO

BACKGROUND: The causes of acute decompensations of patients with systemic autoimmune diseases are not well known. AIM: To describe the causes for consultation in an emergency room of patients with systemic autoimmune diseases. MATERIAL AND METHODS: Review of medical records of patients with systemic autoimmune diseases, aged over 14 years, consulting in an emergency room of a general hospital during three months. RESULTS: In the study period, 166 patients with systemic autoimmune diseases consulted in the emergency room, of a total of 18,153 consultations (0.9%). Patients with rheumatoid arthritis were those that consulted with higher frequency (37%) followed by patients with systemic lupus erythematosus (21%). The most common causes for consultation were cardiovascular diseases in 25%, followed by digestive disorders in 15%. The most common diagnosis was chest pain with suspected ischemic heart disease in 36%. No differences in cardiovascular risk factors were observed between those patients consulting for cardiovascular diseases and those consulting for other causes. CONCLUSIONS: The most common cause of consultation in the emergency room of patients with systemic autoimmune diseases is cardiovascular.


Assuntos
Doenças Autoimunes/terapia , Serviço Hospitalar de Emergência/estatística & dados numéricos , Adulto , Idoso , Idoso de 80 Anos ou mais , Doenças Autoimunes/classificação , Chile , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Fatores de Risco , Centros de Atenção Terciária , Adulto Jovem
8.
Eur J Emerg Med ; 21(5): 380-3, 2014 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-24220140

RESUMO

The aim of the present study is to describe the clinical and epidemiological characteristics, complications and outcome of patients with haemophilia and acute head injury (AHI) at the emergency department (ED), and develop a protocol to prevent early and late complications. This is a retrospective cohort study including all patients with haemophilia and AHI admitted to the ED. We identified 26 patients with AHI. A computed tomography scan was carried out on all patients at admission, and again on two patients (with neurosurgical complications) 48 h later. The discharge diagnosis was as follows: 3.8% subdural haematoma, 3.8% cerebellar epidural haematoma and 92.3% uncomplicated AHI. We propose the following protocol: a computed tomography scan upon arrival and another within 48 h post-AHI, unless there is an absence of clinical symptoms. In addition, all patients must self-administer a clotting factor as soon as possible and be observed in the ED for at least 48 h.


Assuntos
Traumatismos Craniocerebrais/complicações , Hemofilia A/complicações , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Criança , Pré-Escolar , Protocolos Clínicos , Traumatismos Craniocerebrais/diagnóstico , Traumatismos Craniocerebrais/diagnóstico por imagem , Traumatismos Craniocerebrais/terapia , Serviço Hospitalar de Emergência , Abscesso Epidural/complicações , Feminino , Hematoma Subdural/complicações , Humanos , Lactente , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Tomografia Computadorizada por Raios X , Resultado do Tratamento , Adulto Jovem
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