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Risk factors related to the workplace environment are being studied to identify positive associations with hypertension disorders. Hypertension is considered as one of the main modifiable risk factors and most important public health issues. The study aims to describe the prevalence of hypertension and associate it with sociodemographic, labour and health aspects, in the health-care nursing staff of an emergency hospital.Cross-sectional study enrolled 606 nursing workers. The data were collected from February to June, and the analysis was conducted in November 2010. Arterial blood pressure, body mass index (BMI), waist-to-hip ratio (WHR) were assessed, and sociodemographic and labour variables were investigated by means of a questionnaire. The data were analysed by descriptive statistics, univariate and multivariate analysis. The prevalence of hypertension was 32% (n = 388), with positive associations with age > 49 years (OR = 2.55 (CI: 1.19 to 5.43)), ethnicity (non-white) (odds ratio (OR) = 2.22, confidence interval (CI) 1.16 to 1.24), BMI (OR = 2.24 (CI: 1.25 to 4.01)) and WHR (OR = 2.65 (CI: 1.95 to 7.763)). Arterial hypertension was frequent in the nursing staff of this emergency hospital. Further studies are needed to better understand the relationship between occupational aspects and arterial hypertension.

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OBJETIVOS: Descrever os medicamentos mais frequentemente utilizados por pacientes em hemodiálise e identificar potenciais interações medicamentosas entre os mesmos.MÉTODOS: Estudo transversal realizado em uma unidade hospitalar de hemodiálise. Cada combinação de medicamentos prescritos foi analisada no programa Micromedex©2014 Truven Health Analytics (Michigan, Estados Unidos), para identificação de potenciais interações medicamentosas e classificação de acordo com a gravidade.RESULTADOS: Foram incluídos 65 pacientes. A média de idade foi de 59,1±14,7 anos e 50,8% eram mulheres. A ocorrência de polifarmácia foi de 87,7%, com média de 6,3±3,1 medicamentos por paciente, sendo os mais frequentes o carbonato de cálcio (n=55, 84,6%) e a eritropoetina (n=47, 72,3%). A prevalência de potenciais interações medicamentosas foi de 56,9%, com mediana de uma interação por paciente, e a maioria foi classificada como moderada (49,1%), sendo as mais frequentes atenolol/carbonato de cálcio (n=9, 8,0%) e ferro/carbonato de cálcio (n=9, 8,0%). A presença de potenciais interações medicamentosas moderadas ou importantes e o número destas associaram-se com a quantidade de medicamentos utilizados por paciente (p<0,001).CONCLUSÕES: A prevalência de potenciais interações medicamentosas nos pacientes em hemodiálise foi elevada e esteve intimamente ligada ao número de medicamentos utilizados por cada paciente. A população com doença renal crônica necessita do uso de vários medicamentos, portanto é importante a seleção cuidadosa de alternativas terapêuticas, através da assistência farmacêutica, para o uso eficaz, racional e seguro de medicamentos.

AIMS: To describe the drugs most frequently used by patients in hemodialysis and to identify potential drug-drug interactions.METHODS: Cross-sectional study conducted in a hospital hemodialysis unit. Each combination of drugs prescription was analyzed in Micromedex©2014 Truven Health Analytics (Michigan, United States), to identify potential drug-drug interactions and classify them according to severity.RESULTS: Sixty-five patients were included. The mean age was 59.1±14.7 years and 50.8% were women. The occurrence of polypharmacy was 87.7%, with average of 6.3±3.1 medications/patient, the most frequent being calcium carbonate (n=55, 84.6%) and erythropoietin (n=47, 72.3%). The prevalence of potential drug-drug interactions was 56.9%, with median of one interaction per patient, and most were classified as moderate (49.1%) being the most frequent atenolol/calcium carbonate (n=9, 8.0%) and iron/calcium carbonate (n=9, 8.0%). The presence and number of potential moderate or important drug-drug interactions were significantly associated with the number of drugs used by the patient (P<0.001).CONCLUSIONS: The prevalence of potential drug-drug interactions was high and closely linked to the number of drugs used by each patient. The population with chronic kidney disease requires the use of various drugs, therefore the careful selection of therapeutic alternatives through pharmaceutical assistance is important for effective, rational and safe use of medicines.

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Cross-sectional study aimed to analyse and compare the correlation between the Therapeutic Intervention Scoring System (TISS)-28 and Nine Equivalents of Nursing Manpower Use (NEMS) indicators with a sample of 725 patients, for which data was collected from the computerized system of a university hospital. The findings of the present study well demonstrated a strong correlation between the TISS-28 and NEMS, both at the time of patient admission and discharge (0.888 and 0.885; P < 0.001), although there is a dispersion of 21% in the data and established cut-off points to discriminate with greater power the death and no death scenarios. Further research is still necessary to confirm the possibility of replacing the TISS-28 scoring instrument with NEMS.

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Streptococcus agalactiae causes a rare and often fatal peritonitis in continuous ambulatory peritoneal dialysis (CAPD). A 52-year-old white female with Alport and chronic kidney disease was initiated on CAPD treatment. Nineteen months later she had a S. agalactiae peritonitis identified and received initially gentamicin-cephalothin, which was changed to ceftazidime, tobramycin, and vancomycin. Recovery started after peritoneal catheter removal. After 3 weeks, severe leucopenia occurred. Granulokine and steroids were given. Six weeks later, she felt well and an abdominal video laparoscopic procedure disclosed a diffuse peritoneal fibrosis, precluding CAPD resumption. She is now doing well on hemodialysis (HD).

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