RESUMO

POEMS is an acronym for a syndrome characterized by osteosclerotic myeloma: polyneuropathy, organomegaly, endocrinopathy, monoclonal protein and skin changes. Hypothyroidism, hypogonadism, diabetes mellitus and adrenal failure can be associated to POEMS syndrome. We report a 39 years old women with monoclonal gammopathy and paraparesis caused by a polyneuropathy, in whom a POEMS syndrome was diagnosed and treated with dexamethasone. The patient had a secondary amenorrhea and a clinical hypothyroidism with negative antithyroidal antibodies. Substitutionwith levothyroxine was started.

Assuntos

Humanos , Feminino , Adulto , Amenorreia/etiologia , Hipotireoidismo/etiologia , Síndrome POEMS/diagnóstico , Dexametasona/uso terapêutico , Hipotireoidismo/tratamento farmacológico , Síndrome POEMS/tratamento farmacológico , Tiroxina/uso terapêutico