RESUMO

We present two cases of Leishmania (V) panamensis in returning travelers from Central America successfully treated with miltefosine. The couple presented with ulcerative skin lesions nonresponsive to antibiotics. Skin biopsy with polymerase chain reaction (PCR) revealed L. (V) panamensis. To prevent the development of mucosal disease and avoid the inconvenience of parental therapy, we treated both patients with oral miltefosine. We suggest that miltefosine represents an important therapeutic alternative in the treatment of cutaneous lesions caused by L. panamensis and in preventing mucosal involvement.

Assuntos

Antiprotozoários/administração & dosagem , Leishmania guyanensis/isolamento & purificação , Leishmaniose Cutânea/diagnóstico , Fosforilcolina/análogos & derivados , Administração Oral , Adulto , Biópsia , América Central , Feminino , Humanos , Leishmaniose Cutânea/tratamento farmacológico , Leishmaniose Cutânea/parasitologia , Masculino , Fosforilcolina/administração & dosagem , Reação em Cadeia da Polimerase , Pele/parasitologia , Viagem