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J Biophotonics ; 17(4): e202300412, 2024 04.
Artigo em Inglês | MEDLINE | ID: mdl-38253349

RESUMO

This study aimed to evaluate the clinical evolution of patients with diabetic foot ulcer treated with antimicrobial photodynamic therapy (aPDT) using the Bates-Jensen (BJ) scale. A total of 21 patients were monitored, with an average age of 58 years. Patients underwent the standard treatment protocol of the institution, supplemented with aPDT utilizing 0.01% methylene blue (MB) and laser irradiation (660 nm, 100 mW, 6 J per point). Following aPDT, the lesions were protected with hydrofiber dressings containing silver. The Bates-Jensen Scale was employed at pre-treatment and post-aPDT sessions to assess lesion progression. The results demonstrated a significant difference between pre- and post-treatment values in the overall BJ score. The use of MB in aPDT proved to be an effective, safe, well-tolerated treatment with high patient adherence and the potential for implementation in the care of diabetic foot conditions.


Assuntos
Anti-Infecciosos , Diabetes Mellitus , Pé Diabético , Fotoquimioterapia , Humanos , Pessoa de Meia-Idade , Fármacos Fotossensibilizantes/uso terapêutico , Pé Diabético/tratamento farmacológico , Fotoquimioterapia/métodos , Resultado do Tratamento , Azul de Metileno/farmacologia , Azul de Metileno/uso terapêutico
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