RESUMO
OBJETIVO: Avaliar se o uso de salbutamol inalatório através de inalador dosimetrado acoplado a espaçadores de grande volume com tratamento antiestático na espirometria com prova broncodilatadora modifica os resultados do teste quando comparado à técnica usual (sem espaçador). MÉTODOS: Estudo prospectivo envolvendo 24 pacientes, com idades entre 18 e 45 anos e suspeita clínica de asma, atendidos no Ambulatório de Pneumologia do Hospital das Clínicas da Universidade Federal de Minas Gerais, em Belo Horizonte (MG). Os pacientes foram submetidos a duas espirometrias com prova broncodilatadora realizadas com e sem o uso de espaçador de grande volume. RESULTADOS: Não houve diferença significativa na variação do VEF1 antes e após o uso de broncodilatador entre as duas técnicas (ΔVEF1 média = 0,01 L; IC95 por cento: -0,05 a 0,06; p = 0,824). Não houve diferença estatisticamente significativa entre as duas técnicas em relação ao resultado qualitativo da prova broncodilatadora (p = 1,00). Houve concordância dos resultados da prova broncodilatadora entre as técnicas (coeficiente kappa = 0,909; p < 0,005). CONCLUSÕES: De acordo com os resultados deste estudo, a utilização de espaçadores de grande volume não modificou de forma significativa os resultados da prova broncodilatadora.
OBJECTIVE: To evaluate whether the use of inhaled albuterol via a metered-dose inhaler with a large-volume spacer with antistatic treatment modifies the bronchodilator test results when compared with the usual technique (no spacer). METHODS: A prospective study involving 24 patients, 18-45 years of age, clinically suspected of having asthma, and under treatment at the Outpatient Pulmonary Clinic of the Federal University of Minas Gerais Hospital das Clínicas, located in the city of Belo Horizonte, Brazil. All of the patients underwent two bronchodilator tests: one with and one without the use of a large-volume spacer. RESULTS: There was no significant difference in the variation of FEV1 prior to and after bronchodilator use between the two techniques (mean ΔFEV1 = 0.01 L; 95 percent CI: -0.05 to 0.06; p = 0.824). No statistically significant difference was found between the two techniques regarding the qualitative results on the bronchodilator test (p = 1.00). There was concordance between the techniques in terms of the bronchodilator test results (kappa coefficient = 0.909; p < 0.005). CONCLUSIONS: According to the results of this study, the use of large-volume spacers does not significantly modify bronchodilator test results.
Assuntos
Adolescente , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Adulto Jovem , Albuterol/administração & dosagem , Asma/tratamento farmacológico , Testes de Provocação Brônquica/métodos , Broncodilatadores/administração & dosagem , Espaçadores de Inalação , Espirometria , Asma/fisiopatologia , Desenho de Equipamento , Volume Expiratório Forçado/efeitos dos fármacos , Estudos Prospectivos , Eletricidade EstáticaRESUMO
OBJECTIVE: To evaluate whether the use of inhaled albuterol via a metered-dose inhaler with a large-volume spacer with antistatic treatment modifies the bronchodilator test results when compared with the usual technique (no spacer). METHODS: A prospective study involving 24 patients, 18-45 years of age, clinically suspected of having asthma, and under treatment at the Outpatient Pulmonary Clinic of the Federal University of Minas Gerais Hospital das Clínicas, located in the city of Belo Horizonte, Brazil. All of the patients underwent two bronchodilator tests: one with and one without the use of a large-volume spacer. RESULTS: There was no significant difference in the variation of FEV1 prior to and after bronchodilator use between the two techniques (mean ΔFEV1 = 0.01 L; 95% CI: -0.05 to 0.06; p = 0.824). No statistically significant difference was found between the two techniques regarding the qualitative results on the bronchodilator test (p = 1.00). There was concordance between the techniques in terms of the bronchodilator test results (kappa coefficient = 0.909; p < 0.005). CONCLUSIONS: According to the results of this study, the use of large-volume spacers does not significantly modify bronchodilator test results.