RESUMO
Cercariae of Schistosoma mansoni after intraperitoneal inoculation, developed and reached the sexual maturation in that site with egg production. In the AKR/J strain of mice, 7.7 of the peritoneal recovered females showed normal eggs in the uterus. No evidence of hemoglobinic pigment in their digestive tract was observed in the peritoneal recovered parasites from both strains (AKR/J and SWISS). This fact suggests that the parasites can develop without red blood cells ingestion. On the other hand, the development of the parasite with egg production in the peritoneal cavity of the AKR/J mouse reinforces the data that the lung phase is not necessary for the development of the parasite.
Assuntos
Animais , Masculino , Feminino , Camundongos , Camundongos Endogâmicos AKR/parasitologia , Cavidade Peritoneal , Schistosoma mansoni , Ovário , Interações Hospedeiro-Parasita , Maturidade SexualAssuntos
Animais , Masculino , Camundongos , Dexametasona , Schistosoma mansoni , Larva , Schistosoma mansoni , Fatores de TempoRESUMO
The peritoneal cavity of laboratory mice was used to study the phenomenon of host cell adhesion to different evolutive stages of the Schistosoma mansoni (cercaria, adult worm, developing and mature eggs, miracidium, young and mature daughter sporocysts). Material recovered from the peritoneal cavity 30 and 180 min after the inoculation of each evolutive form was examined with the help of a stereomicroscope. The free swimming larvae (cercaria and miracidium), and the evolutive forms producing such larvae (mature egg and mature daughter sporocyst) elicited the host cell adhesion phenomenon. In all forms but cercariae the adherent cells remained as so till 180 minutes after inoculation
Assuntos
Animais , Schistosoma mansoni/patogenicidade , Adesão Celular , Interações Hospedeiro-Parasita , Larva/crescimento & desenvolvimento , Larva/patogenicidade , Camundongos , Cavidade Peritoneal/citologia , Cavidade Peritoneal/parasitologia , Schistosoma mansoni/crescimento & desenvolvimento , Esquistossomose mansoni/parasitologia , Fatores de TempoRESUMO
Camundongos albinos heterozigotos foram inoculados com a cepa IFLA/BR/67/PH8 de Leishmania mexicana amazonensis (10 elevado a 5 promastigotas por camundongo) e, depois que as lesöes cutâneas estavam bem caracterizadas (78 dias após), com a cepa LE de Schistosoma mansoni (cerca de 30 cercárias por camundongo). Os camundongos controle receberam apenas a inoculaçäo pelo helminto. Durante as necrópsias, realizadas 63 dias após a infecçäo pelo S. mansoni, um aumento significativo no número de vermes foi observado nos animais com infecçäo concomitante pela L. m. amazonensis. Os achados säo atribuídos a uma possível alteraçäo na resposta imune do hospedeiro à infecçäo pelo S. mansoni, alteraçäo essa devida à infecçäo leishmaniótica prévia.