RESUMO
Introduction: Protein-caloric malnutrition is a public health concern in certain areas of the Brazil. It can affect growth, the auditory nervous system development and, consequently, the cognition. This study compared the Brainstem Auditory Evoked Potential (BAEP) between malnourished and eutrophic children.Methods: A total of 111 children, aged 0-60 months, were examined: 57 were malnourished, according to the World Health Organization criteria, and 54 were normo-nourished. All the subjects underwent otorhinolaryngological evaluations and had acoustic immittance and transient evoked otoacoustic emissions within the normal range. The BAEP responses to click and tone burst stimuli were recorded at intensities of 80, 60, 40, and 30 dBNA.Results: We observed that latencies of I, III, and V waves and interpeaks III-V at 80 dBNA with click stimuli were significantly higher in all malnourished children when compared to those in the eutrophic children, as was the I-V interval in the 0- to 24-month group. The V-wave latencies at those intensities were also significantly higher in malnourished children.Conclusions: Malnourished children presented changes in BAEP characterized by delayed wave latency and interpeak intervals when compared to eutrophic children, suggesting alterations in both peripheral and central auditory pathways development and maturation.
Assuntos
Encéfalo/crescimento & desenvolvimento , Potenciais Evocados Auditivos do Tronco Encefálico/fisiologia , Desnutrição/fisiopatologia , Encéfalo/fisiopatologia , Brasil , Pré-Escolar , Feminino , Humanos , Lactente , Recém-Nascido , Masculino , Sistema Nervoso , Estado Nutricional/fisiologiaRESUMO
UNLABELLED: Auditory neuropathy spectrum disorder (ANSD) is characterized by impairment of the auditory nerve associated with preservation of outer hair cell function. OBJECTIVE: To establish the prevalence of ANSD in subjects with sensorineural hearing loss (SNHL). METHOD: This retrospective study was carried out between 2010 and 2012 and included the charts of 2,292 individuals with SNHL. Data from otolaryngological and audiological examinations based on pure-tone and speech audiometry, impedance tests, otoacoustic emissions (OAEs), and brainstem auditory evoked potentials (BAEPs) were collected. INCLUSION CRITERIA: presence of OAEs and/or cochlear microphonic (CM); absent or altered BAEPs, and normal MRI scans of the brain. RESULTS: Twenty-seven (1.2%) of the 2,292 subjects with SNHL had ANSD (37% males; 63% females). Mild SNHL was seen in 29.6% of the individuals with ANSD; 55.5% had moderate SNHL; 7.4% had severe SNHL; and 7.5% had profound SNHL. In terms of age, 14.8% were aged between zero and 20 years, 44.1% were 41 to 60 years old, and 7.4% were above the age of 60. CONCLUSION: ANSD was seen in 1.2% of the individuals with SNHL included in this study.
Assuntos
Perda Auditiva Central/complicações , Perda Auditiva Neurossensorial/etiologia , Adolescente , Adulto , Distribuição por Idade , Audiometria de Tons Puros , Criança , Pré-Escolar , Potenciais Evocados Auditivos do Tronco Encefálico/fisiologia , Feminino , Perda Auditiva Central/diagnóstico , Perda Auditiva Central/epidemiologia , Perda Auditiva Central/fisiopatologia , Perda Auditiva Neurossensorial/fisiopatologia , Humanos , Lactente , Recém-Nascido , Masculino , Pessoa de Meia-Idade , Emissões Otoacústicas Espontâneas/fisiologia , Prevalência , Estudos Retrospectivos , Índice de Gravidade de DoençaRESUMO
Oespectro da neuropatia auditiva (ENA) caracteriza-se pelo acometimento do nervo auditivo, associado à preservação da função das células ciliadas externas cocleares. OBJETIVO: Determinar a prevalência do ENA em sujeitos com perda auditiva neurossensorial (PANS). MÉTODO: Estudo retrospectivo realizado de 2010 a 2012, pela análise dos prontuários de 2.292 sujeitos com PANS. Foram coletados dados das avaliações otorrinolaringológica e audiológica, por meio da audiometria tonal e vocal, imitanciometria, Emissões Otoacústicas (EOAs) e Potencial Evocado Auditivo de Tronco Encefálico (PEATE). Critérios de inclusão: presença das EOAs e/ou Microfonismo Coclear (MC); ausência ou alterações nas ondas do (PEATE) e ressonância nuclear magnética cerebral normal. RESULTADOS: Entre os 2.292 sujeitos com PANS, 27 (1,2%) apresentaram ENA, sendo 37% masculino e 63% feminino. Entre os sujeitos com ENA, 29,6% tinham PANS leve; 55,5% moderada; 7,4% grave e 7,5% profunda. Em relação à faixa etária, 14,8% estavam entre 0 e 20 anos, 33,4% entre 21 e 40 anos, 44,4% entre 41 e 60 anos e 7,4% acima de 60 anos. CONCLUSÃO: A prevalência do ENA neste estudo foi de 1,2% em sujeitos com PANS.
Auditory neuropathy spectrum disorder (ANSD) is characterized by impairment of the auditory nerve associated with preservation of outer hair cell function. OBJECTIVE: To establish the prevalence of ANSD in subjects with sensorineural hearing loss (SNHL). METHOD: This retrospective study was carried out between 2010 and 2012 and included the charts of 2,292 individuals with SNHL. Data from otolaryngological and audiological examinations based on pure-tone and speech audiometry, impedance tests, otoacoustic emissions (OAEs), and brainstem auditory evoked potentials (BAEPs) were collected. Inclusion criteria: presence of OAEs and/or cochlear microphonic (CM); absent or altered BAEPs, and normal MRI scans of the brain. RESULTS: Twenty-seven (1.2%) of the 2,292 subjects with SNHL had ANSD (37% males; 63% females). Mild SNHL was seen in 29.6% of the individuals with ANSD; 55.5% had moderate SNHL; 7.4% had severe SNHL; and 7.5% had profound SNHL. In terms of age, 14.8% were aged between zero and 20 years, 44.1% were 41 to 60 years old, and 7.4% were above the age of 60. CONCLUSION: ANSD was seen in 1.2% of the individuals with SNHL included in this study.