RESUMO

Foot-and-Mouth Disease serotype O circulated endemically in Ecuador for many years, with an upsurge occurring in 2009. This manuscript describes retrospectively in vitro and in vivo laboratory studies to predict the field effectiveness of a commercial FMD vaccine to protect against the field strain, and explains the key actions and epidemiological strategies followed by the country to control the disease. The results established that the use of a good quality oil vaccine, manufactured with strains that were isolated long ago: O1 Campos Br/58 and A24 Cruzeiro Br/55; combined with the correct epidemiological strategies, are useful to control field strains when used in periodic biannual vaccination campaigns.

Assuntos

Doenças dos Bovinos/prevenção & controle , Febre Aftosa/prevenção & controle , Vacinas Virais/uso terapêutico , Sequência de Aminoácidos , Animais , Anticorpos Antivirais/sangue , Proteínas do Capsídeo/genética , Bovinos , Doenças dos Bovinos/virologia , Proteção Cruzada , Equador , Vírus da Febre Aftosa/classificação , Vacinação/veterinária , Vacinas Virais/imunologia