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This literature review explores cutting-edge microencapsulation techniques designed to enhance the antimicrobial efficacy of essential oils in dairy products. As consumer demand for natural preservatives rises, understanding the latest advancements in microencapsulation becomes crucial for improving the shelf life and safety of these products. The bibliometric analysis utilized in this review highlighted a large number of documents published on this topic in relation to the following keywords: essential oils, AND antimicrobials, AND dairy products, OR microencapsulation. The documents published in the last 11 years, between 2013 and 2023, showed a diversity of authors and countries researching this topic and the keywords commonly used. However, in the literature consulted, no study was identified that was based on bibliometric analysis and that critically evaluated the microencapsulation of essential oils and their antimicrobial potential in dairy products. This review synthesizes findings from diverse studies, shedding light on the various encapsulation methods employed and their impact on preserving the quality of dairy goods. Additionally, it discusses the potential applications and challenges associated with implementation in the dairy industry. This comprehensive analysis aims to provide valuable insights for researchers, food scientists, and industry professionals seeking to optimize the use of essential oils with antimicrobial properties in dairy formulations.

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Oligobregma represents the most speciose genus of Scalibregmatidae with 17 valid species. Most of them occur at great depths and are found living on soft bottoms. Here, we present the descriptions of O. nonatoi sp. nov., O. cruzae sp. nov., and O. bakkeni sp. nov., sampled from the Brazilian continental shelf and slope, and a key to all species of Oligobregma. O. nonatoi sp. nov. differs from its congeners by the presence of a triangular prostomium with short rounded horns, acicular spines on notopodia of chaetigers 14 and on neuropodia of chaetigers 13. Oligobregma cruzae sp. nov. can be distinguished by the presence of a quadrangular prostomium with two short, rounded horns, acicular spines on chaetigers 14, and lyrate chaetae from chaetiger 5. Finally, O. bakkeni sp. nov. is unique among its congeners by the presence of acicular spines with rounded tips. This is the first record of this genus along the Brazilian coast and the specimens were collected on Esprito Santo, Campos and Santos sedimentary basins, both located in Brazilian southeast region. The sampling campaigns were carried out in scientific expeditions related to two research projects: Santos Project Santos Basin Environmental Characterization and Ambes Project Esprito Santo Basin Assessment Project, both coordinated by CENPES/PETROBRAS.

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One of the main disturbances caused by coastal nuclear power plants is the discharge of thermal effluents capable of affecting a number of marine systems, including macroalgal forests that support key ecosystem services such as carbon uptake, fisheries increment and coastal protection. This study aimed at describing the long-term trend (1992-2022) in the abundance of Sargassum forests from sites located inside and outside areas affected by the thermal effluent discharged by the Brazilian Nuclear Power Station (BNPS) and at evaluating the relationship between Sargassum cover and seawater temperature. This information is interesting to provide insights on whether and how Sargassum populations would likely be affected by increasing temperature due to climate change. We detected a long-term decline in Sargassum cover inside, but not outside the area affected by the BNPS thermal plume. Mean summer surface seawater temperature above 30 °C was identified as an important factor driving the decline of Sargassum abundance. This study highlights the impact caused by decades of discharge of the BNPS thermal effluent on Sargassum forests, which leads to predict the likely disappearance of marine forests under a climate change scenario in other sites situated in warm temperate regions.

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Pseudoscalibregma Ashworth, 1901 is a small genus of the family Scalibregmatidae Malmgren, 1867. Currently, a total of eight valid species are accepted. Of these, the majority are found at great depths. This work contains the first report of Pseudoscalibregma to the Brazilian coast, with the description of three new species: Pseuscalibregma ermindae sp. nov., P. magalhaesi sp. nov. and P. parapari sp. nov. The material was sampled from the Brazilian southeast region, on Campos and Santos sedimentary basins, during scientific expeditions called Santos ProjectSantos Basin Environmental Characterization and Ambes ProjectEsprito Santo Basin Assessment Project, both coordinated by PETROBRAS/CENPES. We also include an identification key to Pseudoscalibregma species.

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Fertigation is widely used in seedling production for different crops, including passion fruit. There is no consensus on the ideal nutrient solution, and as such, nurseries have used fertigation empirically. This study assessed the electrical conductivity of nutrient solution containing macro and micronutrients in passion fruit seedling production and compared it with commercially used fertigation. A completely randomized design was used, with five treatments and six repetitions. Four electrical conductivities (0.5, 1.0, 2.0 and 4.0 dS m-1) of a complete nutrient solution and an additional treatment (commercial nutrient solution) were analyzed. Daily fertigation with a complete nutrient solution (macro and micronutrients) at electrical conductivities between 2.6 and 3.3 dS m-1 followed by two daily irrigations are efficient at producing FB 300 "Araguari" passion fruit seedlings in coconut fiber substrate, with benefits such as greater biomass and better Dickson quality index when compared to commercial nutrient solution.

A fertirrigação é amplamente utilizada na produção de mudas de várias culturas, inclusive o maracujazeiro. Não existe consenso sobre qual solução nutritiva deve ser adotada na produção de mudas de maracujazeiro, mas por causa disso, viveiristas têm usado a fertirrigação empiricamente. O objetivo deste trabalho foi avaliar condutividades elétricas de solução nutritiva com macros e micronutrientes na produção de mudas de maracujazeiro e compará-las com uma fertirrigação adotada comercialmente. Foi utilizado delineamento experimental inteiramente casualizado, com cinco tratamentos e seis repetições. Foram estudadas quatro condutividades elétricas (0,5; 1,0; 2,0 e 4,0 dS m-1) de solução nutritiva completa e um tratamento adicional (solução nutritiva adotada comercialmente). Em substrato à base de fibra de coco, fertirrigações diárias com solução nutritiva completa (macro e micronutrientes), com condutividades elétricas entre 2,6 a 3,3 dS m-1, seguidas de duas irrigações diárias são eficientes na produção de mudas de maracujazeiro FB 300 "Araguari", inclusive com vantagens, como maior biomassa e índice de qualidade de Dickson em relação à solução nutritiva comercial.

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OBJECTIVES: This study aimed to analyze, in the São Paulo state of Brazil, time trends in prevalence, neonatal mortality, and neonatal lethality of central nervous system congenital malformations (CNS-CM) between 2004 and 2015. METHODS: Population-based study of all live births with gestational age ≥22 weeks and/or birthweight ≥400 g from mothers living in São Paulo State, during 2004-2015. CNS-CM was defined by the presence of International Classification Disease 10th edition codes Q00-Q07 in the death and/or live birth certificates. CNS-CM was classified as isolated (only Q00-Q07 codes), and non-isolated (with congenital anomalies codes nonrelated to CNS-CM). CNS-CM associated neonatal death was defined as death between 0 and 27 days after birth in infants with CNS-CM. CNS-CM prevalence, neonatal mortality, and lethality rates were calculated, and their annual trends were analyzed by Prais-Winsten Model. The annual percent change (APC) with 95% confidence interval (95%CI) was obtained. RESULTS: 7,237,628 live births were included in the study and CNS-CM were reported in 7526 (0.1%). CNS-CM associated neonatal deaths occurred in 2935 (39.0%). Isolated CNS-CM and non-isolated CNS-CM were found respectively in 5475 and 2051 livebirths, with 1525 (28%) and 1410 (69%) neonatal deaths. CNS-CM prevalence and neonatal lethality were stationary, however neonatal mortality decreased (APC -1.66; 95%CI -3.09 to -0.21) during the study. For isolated CNS-CM, prevalence, neonatal mortality, and lethality decreased over the period. For non-isolated CNS-CM, the prevalence increased, neonatal mortality was stationary, and lethality decreased during the period. The median time of CNS-CM associated neonatal deaths was 18 h after birth. CONCLUSIONS: During a 12-year period in São Paulo State, Brazil, neonatal mortality of infants with CNS-CM in general and with isolated CNS-CM showed a decreasing pattern. Nevertheless CNS-CM mortality remained elevated, mostly in the first day after birth.

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This study aimed to examine the benthic structure of Guanabara Bay's (GB) rocky shores through Functional Diversity (FD) perspective. Over a five-year period, benthic communities were periodically examined using photographic samples from the meso-littoral zone. FD were analysed using the Rao Index of marine macroalgae and benthic invertebrates' functional groups (FGs) and their relationship was investigated through null models, considering temporal, geographical, and environmental variations. The entrance site exhibited exclusive FGs and overlap niches more than expected by chance, while the inner site had a higher frequency of Bacterial Biofilm and predominance of competitive exclusion. Orthophosphate and nitrate showed significant correlations with FGs inside the bay, whereas average irradiance and rainfall were at the entrance. A functional gradient was registered, with higher Rao's Index values at the entrance compared to the inner site, probably due to increased anthropogenic disturbance and abundance of FGs with opportunistic life strategies inside GB.

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The freshwater/brackish amphipod Quadrivisio lutzi inhabits coastal lagoons, highly unstable environments subject to sudden inflow of marine water. Our aim was to evaluate how the genetic composition varies in these populations. Brazilian populations were compared by 16S rRNA and COI gene sequences. The genetic structure of four Rio de Janeiro amphipod populations was evaluated during the period of 2011-2019 by COI. Rio de Janeiro population was compared with Alagoas and São Paulo populations, which was genetically distinct, at species level (16S, d > 7%; COI, d >14%). The genetic structure in Rio de Janeiro showed the Imboassica subpopulation as the most divergent (Imboassica & Carapebus, F ST = 0.238), followed by Lagamar population (Lagamar & Carapebus, F ST = 0.049). The geographic distance and urbanization around these lagoons explain the degree of genetic isolation of these amphipod subpopulations. Paulista and Carapebus populations were not structured. Temporal variation in haplotype number and frequency were evident in both populations that were evaluated (Carapebus and Imboassica). Changes in salinity and water volume variation at these lagoons may be responsible for the observed changes in genetic composition, which may be the results of genetic drift effects over temporally fluctuating size subpopulations, without loss of genetic diversity.

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The Antarctic environment has special characteristics that influence the local marine life. The benthic organisms, adapted to these extreme conditions of life, are subject nowadays to effects of climate change. Recently, the consequences of glacier retreat on these assemblages have been observed in many West Antarctic Peninsula (WAP) regions, including King George Island (KGI). This study described the spatial variation of the benthic macrofauna in different areas of the Martel Inlet (Admiralty Bay - KGI), at depths around 25-30 m. Sampling was done in January 2001 at ten stations classified in localities according to their proximity to ice-margin/coastline in marine-terminating glacier (MTG), terrestrial-terminating glacier (TTG) and ice-free area (IFA). The total density and the abundance of annelids, nematodes, peracarid crustaceans and bivalves were higher at IFA stations. The locality discrimination by taxa and species was independent of available environmental/sedimentary conditions or was the result of unmeasured variables or species life history processes not assessed herein. Considering that our findings were obtained 21 years ago, they will be especially useful for comparing future studies of benthic assemblage responses to the influence of climate change and continuous glacier retreats in the WAP region.

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Objectives: To examine drug overdose records in Brazil from 2000 to 2020, analyzing trends over time in overdoses and overall sociodemographic characteristics of the deceased. Methods: Using data from the Brazilian Mortality Information System (Sistema de Informações sobre Mortalidade), we identified records from 2000-2020 in which the underlying cause-of-death was one of the following codes: X40-X45 (accidental poisoning), X60-X65 (intentional poisoning), or Y10-Y15 (undetermined intentionality poisoning). The Brazilian dataset included 21,410 deaths. We used joinpoint regression analysis to assess changes in trends over time. Results: People who died of drug overdoses in Brazil between 2000 and 2020 had a mean age of 38.91 years; 38.45% were women, and 44.01% were identified as White. Of the overdose deaths, 44.70% were classified as intentional and 32.12% were classified as unintentional. Among the identified drugs, stimulants were the most common class. However, most records did not report which drug was responsible for death. Conclusion: Sociodemographic trends in overdose deaths in Brazil must guide country-specific policies. Nevertheless, data collection protocols must be improved, particularly regarding the drug used in overdoses.

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OBJECTIVES: To examine drug overdose records in Brazil from 2000 to 2020, analyzing trends over time in overdoses and overall sociodemographic characteristics of the deceased. METHODS: Using data from the Brazilian Mortality Information System (Sistema de Informações sobre Mortalidade), we identified records from 2000-2020 in which the underlying cause-of-death was one of the following codes: X40-X45 (accidental poisoning), X60-X65 (intentional poisoning), or Y10-Y15 (undetermined intentionality poisoning). The Brazilian dataset included 21,410 deaths. We used joinpoint regression analysis to assess changes in trends over time. RESULTS: People who died of drug overdoses in Brazil between 2000 and 2020 had a mean age of 38.91 years; 38.45% were women, and 44.01% were identified as White. Of the overdose deaths, 44.70% were classified as intentional and 32.12% were classified as unintentional. Among the identified drugs, stimulants were the most common class. However, most records did not report which drug was responsible for death. CONCLUSION: Sociodemographic trends in overdose deaths in Brazil must guide country-specific policies. Nevertheless, data collection protocols must be improved, particularly regarding the drug used in overdoses.

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Introduction: Premature birth, perinatal asphyxia, and infections are the main causes of neonatal death. Growth deviations at birth also affect neonatal survival according to week of gestation at birth, particularly in developing countries. The purpose of this study was to verify the association between inappropriate birth weight and neonatal death in term live births. Methods: This is an observational follow-up study with all term live births from 2004 to 2013 in Sao Paulo State, Brazil. Data were retrieved with the deterministic linkage of death and birth certificates. The definition of very small for gestational age (VSGA) and very large for gestational age (VLGA) used the 10th percentile of 37 weeks and the 90th percentile of 41 weeks + 6 days, respectively, based on the Intergrowth-21st. We measured the outcome in terms of time to death and the status of each subject (death or censorship) in the neonatal period (0-27 days). Survival functions were calculated using the Kaplan-Meier method stratified according to the adequacy of birth weight into three groups (normal, very small, or very large). We used multivariate Cox regression to adjust for proportional hazard ratios (HRs). Results: The neonatal death rate during the study period was 12.03/10,000 live births. We found 1.8% newborns with VSGA and 2.7% with VLGA. The adjusted analysis showed a significant increase in mortality risk for VSGA infants (HR = 4.25; 95% CI: 3.89-4.65), independent of sex, 1-min Apgar score, and five maternal factors. Discussion: The risk of neonatal death in full-term live births was approximately four times greater in those with birth weight restriction. The development of strategies to control the factors that determine fetal growth restriction through planned and structured prenatal care can substantially reduce the risk of neonatal death in full-term live births, especially in developing countries such as Brazil.

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Moderate and late preterm newborns comprise around 85% of live births < 37 weeks gestation. Data on their neonatal mortality in middle-income countries is limited. This study aims to analyze the temporal trend, causes and timing of neonatal mortality of infants with 320/7-366/7 weeks gestation without congenital anomalies from 2004-2015 in the population of São Paulo State, Brazil. A database was built by deterministic linkage of birth and death certificates. Causes of death were classified by ICD-10 codes. Among 7,317,611 live births in the period, there were 545,606 infants with 320/7-366/7 weeks gestation without congenital anomalies, and 5782 of them died between 0 and 27 days. The neonatal mortality rate decreased from 16.4 in 2004 to 7.6 per thousand live births in 2015 (7.47% annual decrease by Prais-Winsten model). Perinatal asphyxia, respiratory disorders and infections were responsible, respectively, for 14%, 27% and 44% of the 5782 deaths. Median time to death was 24, 53 and 168 h, respectively, for perinatal asphyxia, respiratory disorders, and infections. Bottlenecks in perinatal health care are probably associated with the results that indicate the need for policies to reduce preventable neonatal deaths of moderate and late preterm infants in the most developed state of Brazil.

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BACKGROUND: In high- and middle-income countries, mortality associated to congenital diaphragmatic hernia (CDH) is high and variable. In Brazil, data is scarce regarding the prevalence, mortality, and lethality of CDH. This study aimed to analyze, in São Paulo state of Brazil, the temporal trends of prevalence, neonatal mortality and lethality of CDH and identify the time to CDH-associated neonatal death. METHODS: Population-based study of all live births with gestational age ≥ 22 weeks, birthweight ≥400g, from mothers residing in São Paulo State, Brazil, during 2004-2015. CDH definition and its subgroups classification were based on ICD-10 codes reported in the death and/or live birth certificates. CDH-associated neonatal death was defined as death up to 27 days after birth of infants with CDH. CDH prevalence, neonatal mortality and lethality were calculated and their annual percent change (APC) with 95% confidence intervals (95%CI) was analyzed by Prais-Winsten. Kaplan-Meier estimator identified the time after birth that CDH-associated neonatal death occurred. RESULTS: CDH prevalence was 1.67 per 10,000 live births, with a significant increase throughout the period (APC 2.55; 95%CI 1.30 to 3.83). CDH neonatal mortality also increased over the time (APC 2.09; 95%CI 0.27 to 3.94), while the lethality was 78.78% and remained stationary. For isolated CDH, CDH associated to non-chromosomal anomalies and CDH associated to chromosomal anomalies the lethality was, respectively, 72.25%, 91.06% and 97.96%, during the study period. For CDH as a whole and for all subgroups, 50% of deaths occurred within the first day after birth. CONCLUSIONS: During a 12-year period in São Paulo State, Brazil, CDH prevalence and neonatal mortality showed a significant increase, while lethality remained stable, yet very high, compared to rates reported in high income countries.

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ABSTRACT: Sugarcane borer Diatraea saccharalis (F.) is the primary sugarcane pest in Brazil. To estimate the relationship between larvae in sugarcane stalks and captures of male adults of D. saccharalis, we collected samples weekly: (1) adults with one delta trap with three virgin females and three female pupae and (2) larvae in 120 stalks per plot of 12.6 hectares (355 × 355 m). The study was conducted in two sites with five plots each, in the municipalities of Nova Ponte and Tupaciguara, Minas Gerais State, Brazil, from July 2016 to May 2017. Relationships between (1) males trapped per week and the number of larvae outside of stalks (LOS) were estimated and (2) we evaluated climate variables, namely average temperature, average relative air humidity, hours with relative air humidity below 30 %, rainfall and number of rainy days, and adults and larvae of D. saccharalis. We obtained generalized linear models for LOS in autumn and for larvae inside the stalks (LIS) in spring and autumn and trapped males in both sites. A significant and direct relationship between LIS and males trapped allows predicting larvae density based on captures of males. In addition, plant damage can be estimated based on accumulated captures of males. There was a negative relationship between hours of air humidity < 30 % and larvae outside of stalks. Densities of LIS can be estimated from male captures and by the humidity variables in the trapping week. Nevertheless, the models require validation in the field.

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Scalibregmatidae Malmgren, 1867 is a relatively small family of annelids, with only two taxa reported to Brazil. In this work, we expand the scientific knowledge of this group by presenting two new Scalibregma Rathke, 1843 species. The new species S. lanai sp. nov. and S. cinthyae sp. nov. were collected during an expedition to the Campos and Santos oceanographic basins. Scalibregma cinthyae sp. nov. is unique among its congeners by the presence of two rows of paired lobes on the mouths upper and lower lips, whereas S. lanai sp. nov. is unique among its congeners by the presence of two rows of paired lobes on the mouths lower lip, branchiae from chaetigers 35, and lyrate chaetae with equal tynes. We provide an identification key to all Scalibregma species.

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OBJECTIVE: This article aimed to report a temporal series of respiratory distress syndrome (RDS)-associated neonatal mortality rates in preterm live births in São Paulo state, Brazil, and to identify social, maternal, and neonatal characteristics associated with these deaths. STUDY DESIGN: This is a population-based study of all live births with gestational age (GA) between 22 and 36 weeks, birth weight ≥400 g, without congenital anomalies from mothers living in São Paulo state during 2004 to 2015. RDS-associated neonatal mortality was defined as death up to 27 days after birth with ICD-10 codes P22.0 or P28.0. RDS-associated neonatal mortality rate (annual percent change [APC] with 95% confidence intervals [95% CIs]) was analyzed by Prais-Winsten. Kaplan-Meier estimator identified the time after birth that the RDS-associated neonatal death occurred. Poisson's regression model compared social maternal and neonatal characteristics between preterm live births that survived the neonatal period and those with RDS-associated neonatal deaths, with results expressed in incidence rate ratio and 95% CI. RESULTS: A total of 645,276 preterm live births were included in the study, of which 612,110 survived and 11,078 had RDS-associated neonatal deaths. RDS-associated neonatal mortality rate was 17.17 per thousand preterm live births, with a decreasing annual trend (APC: -6.50%; 95% CI: -9.11 to -3.82%). The median time of these deaths was 48 hours after birth. The following risk factors for RDS-associated neonatal death were identified: maternal schooling ≤7 years (1.18; 1.09-1.29), zero to three prenatal care visits (1.25; 1.18-1.32), multiple pregnancy (1.24; 1.16-1.33), vaginal delivery (1.29; 1.22-1.36), GA 22 to 27 weeks (106.35; 98.36-114.98), GA 28 to 31 weeks (20.12; 18.62-21.73), male sex (1.16; 1.10-1.22), and 5-minute Apgar scores of 0 to 3 (6.74; 6.08-7.47) and 4 to 6 (3.97; 3.72-4.23). CONCLUSION: During the study period, RDS-associated neonatal mortality rates showed significant reduction. The relationship between RDS-associated neonatal deaths and social, maternal, and neonatal factors suggests the need for perinatal strategies to reduce prematurity and to improve the initial management of preterm infants. KEY POINTS: · RDS is associated with preterm live births.. · Impact of RDS-associated neonatal mortality in middle-income countries is scarce.. · Qualified perinatal care can reduce RDS-associated neonatal mortality..

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BACKGROUND: Gestational Trophoblastic Disease (GTD) comprises pathological forms of placental trophoblastic tissue proliferation. When benign, they present with hydatidiform moles, and when malignant, they are called Gestational Trophoblastic Neoplasia. With the growth of the practice of digital health, allied to updated therapeutic approaches, the Outpatient Clinic for Gestational Trophoblastic Disease has built a Health Information System (HIS), contributing to the teaching-learning binomial, as well as to self-care. METHODS: This is a cross-sectional and blind technological assessment research for developing SIS-Mola (Website for the medical team and the Application "MolaApp" aimed at patients with GTD). We used the Praxis management approach to manage the application creation project. In the tasks involving real-time chat, a WebSocket layer was created and hosted together with the project's web services, which use the Arch Linux operating system. For the evaluations, we provided questionnaires developed based on the System Usability Scale (SUS), to determine the degree of user satisfaction, with objective questions on the Likert scale. We invited 28 participants for the evaluations, among ABDTG specialist physicians, doctors from the DTG Outpatient Clinic team, and the patients. The study was systematized according to the rules of treatment and follow-up in treating the disease. RESULTS: The tests were conducted from November 2021 to February 2022. The responses obtained on a Likert scale indicated reliability and credibility to the HIS, since the total usability score, measured by the ten questions of the SUS instrument, had a mean of 81.1 (clinicians), 80 (patients) and median of 77.5 for both groups. The sample was characterized according to the variables: age, gender, education, computer knowledge, and profession. CONCLUSION: Developing a HIS in the GTD Outpatient Clinic met the objectives regarding the rules of treatment and follow-up of patients. With these digital tools, it is possible to obtain data about the patient's health, sending information through exams performed and appropriate treatments. The connectivity capacity allows agile care, saving time, costs and solving the displacement problem. The TICs generate natural efficiency for the organization in the flow of service and the formation of a database, improving the quality of the assistance.

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