RESUMO

We investigated the relationship between the level of c-myc mRNA and histologic aggressiveness in thyroid tumors obtained at surgery. In thyroid carcinomas, there was a positive correlation between these two parameters, while in benign tumors there was no correlation between cellularity and the expression of the proto-oncogene c-myc. These results might be useful in the prognosis of thyroid tumors and consequently helpful in the management of the patient.

Assuntos

Genes myc , RNA Mensageiro/metabolismo , Neoplasias da Glândula Tireoide/patologia , Carcinoma Papilar/genética , Carcinoma Papilar/patologia , Carcinoma Papilar, Variante Folicular/genética , Carcinoma Papilar, Variante Folicular/patologia , Humanos , Invasividade Neoplásica , Hibridização de Ácido Nucleico , Prognóstico , Proto-Oncogene Mas , Neoplasias da Glândula Tireoide/genética