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ABSTRACT Due to the high incidence of breast cancer worldwide, it is important to research and understand the physiological and psychological effects of this disease, like fatigue, depression, and capacity to do daily life tasks and how they modify physical activity. This study aimed to analyze the effects of strength training practice on physical fatigue (IMF-20), depression (Beck questionnaire), handgrip strength, and functional performance (time up and go). The sample was composed of 17 women breast cancer survivors, in which 8 volunteers were strength training practitioners for at least 6 months (P), and 9 volunteers were non-practitioners (NP). The T-test identified significant differences (p>0.05) between groups on fatigue (P=7.37±1.76; NP= 10.77±3.41; p=0.02) and depression (P= 8.75±5.20; NP= 14.55±4.21). There was no significant difference between groups on handgrip strength and functional performance.
RESUMO Devido à alta incidência de câncer de mama em todo o mundo, é importante pesquisar e entender os efeitos fisiológicos e psicológicos dessa doença, como fadiga, depressão e capacidade de realizar tarefas da vida diária e como elas se modificam com a atividade física. O objetivo deste estudo foi analisar os efeitos do treinamento de força na fadiga física (IMF-20), depressão (questionário de Beck), força de preensão manual e desempenho funcional (timed up and go). A amostra foi composta por 17 mulheres sobreviventes de câncer de mama, das quais 8 voluntárias eram praticantes de treinamento de força há pelo menos 6 meses (P) e 9 voluntárias eram não-praticantes (NP). O teste T identificou diferenças significativas (p> 0,05) entre os grupos sobre fadiga (P = 7,37 ± 1,76; NP= 10,77 ± 3,41; p = 0,02) e sobre depressão (P= 8,75 ± 5,20; NP= 14,55 ± 4,21). Não houve diferença significativa entre os grupos em força de preensão manual e desempenho funcional.
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ABSTRACT Introduction Prostate cancer is the most prevalent neoplastic disease in men. After diagnosis, different treatment regimens are proposed based on the stage of the cancer. These treatments affect physical and muscle function, quality of life, and prognosis differently. Objectives To assess fatigue, muscle strength, muscle thickness, and muscle quality in prostate cancer survivors undergoing androgen deprivation therapy (ADT). Methods Ten ADT patients, eight non-ADT patients and 18 healthy control subjects were enrolled in this study. Perceived fatigue was assessed through the 20-item Multidimensional Fatigue Inventory. Muscle thickness and quality (e.g., echo intensity) were assessed through B-mode ultrasound. Muscle strength and work capacity were assessed using an isokinetic dynamometer. The groups were compared with one-way ANOVA and Bonferroni adjustment. Results Muscle thickness, peak torque, and work capacity were lower in ADT than in the control group (CON) (p = 0.021; p = 0.005; p <0.001, respectively). ADT showed greater echo intensity than CON (p = 0.005) and N-ADT (p = 0.046). There were no differences between N-ADT and CON in terms of muscle thickness, peak torque, work capacity, and echo intensity (p >0.05). General fatigue was greater in both ADT (p = 0.030) and N-ADT (p = 0.047) compared to CON. Physical fatigue was greater in ADT than CON (p = 0.006). Conclusion ADT patients showed lower levels of muscle function and greater levels of perceived fatigue than healthy control subjects. It appears that muscle function remains lower in ADT patients, even several years after treatment initiation, although this does not apply to non-ADT patients. Level of evidence II; Diagnostic Studies - Investigating a Diagnostic Test.
RESUMO Introdução O câncer de próstata é a doença neoplásica mais frequente nos homens. Após seu diagnóstico, diferentes métodos de tratamento são propostos baseados no estágio do câncer. Esses tratamentos afetam diferentemente a função física e muscular, qualidade de vida e o prognóstico. Objetivos Avaliar a fadiga, força muscular, espessura muscular e a qualidade muscular dos sobreviventes ao câncer de próstata que foram submetidos a terapia de privação androgênica (ADT). Métodos Dez pacientes ADT, oito não ADT (N-ADT) e 18 indivíduos saudáveis no grupo controle (CON) foram inscritos neste estudo. A fadiga percebida foi avaliada através do Multidimensional Fatigue Inventory composto por 20 itens. A espessura e qualidade musculares (eco-intensidade) foram avaliadas através de um aparelho de ultrassom B-mode. A força muscular e a capacidade de trabalho foram avaliadas utilizando um dinamômetro isocinético. Os grupos foram comparados através de ANOVA de um fator e ajuste de Bonferroni. Resultados O grupo ADT apresentou menor espessura muscular, pico de torque e capacidade de trabalho do que o grupo controle (p = 0,021; p = 0,005; p < 0,001, respectivamente). O grupo ADT demonstrou maior eco-intensidade que o grupo controle (p = 0,005) e N-ADT (p = 0,046). Não foram encontradas diferenças entre o grupo N-ADT e CON quanto à espessura muscular, pico de torque, capacidade de trabalho e eco-intensidade (p > 0,05). A fadiga geral foi maior tanto no grupo ADT (p = 0,030) quanto no grupo N-ADT (p = 0,047) quando comparada ao grupo CON. A fadiga física foi maior no grupo ADT do que no grupo CON (p = 0,006). Conclusão Os pacientes submetidos à terapia de privação androgênica demonstraram menores níveis de função muscular e maiores níveis de fadiga percebida do que os indivíduos saudáveis do grupo controle. Parece que a função muscular permanece menor em pacientes submetidos à ADT vários anos após o início do tratamento, o que não ocorre com os pacientes N-ADT. Nível de evidência II; Estudos diagnósticos - Investigação de um exame para diagnóstico.
RESUMEN Introducción El cáncer de próstata es la enfermedad neoplásica más frecuente en los hombres. Después de su diagnóstico, diferentes métodos de tratamiento son propuestos basados en la etapa del cáncer. Estos tratamientos afectan de forma diferente la función física y muscular, la calidad de vida y el pronóstico. Objetivos Evaluar la fatiga, fuerza muscular, espesor muscular, y la calidad muscular de sobrevivientes al cáncer de próstata que fueron sometidos a la terapia de privación de andrógenos (ADT). Métodos Diez pacientes ADT, ocho no ADT (N-ADT) y 18 individuos sanos en el grupo control (CON) fueron inscriptos en este estudio. La fatiga percibida fue evaluada a través del Multidimensional Fatigue Inventory compuesto por 20 ítems. El espesor y calidad muscular (eco intensidad) fueron evaluadas a través de un aparato de ultrasonido B-mode. La fuerza muscular y la capacidad de trabajo fueron evaluadas en un dinamómetro isocinético. Los grupos fueron comparados a través de ANOVA de un factor y ajuste de Bonferroni. Resultados El grupo ADT demostró menor espesor muscular, pico de torque y capacidad de trabajo que el grupo control (p = 0,021; p = 0,005; p <0,001, respectivamente). El grupo ADT demostró mayor eco intensidad que el grupo control (p = 0,005) y N-ADT (p = 0,046). No se encontraron diferencias entre el grupo N-ADT y el grupo CON, con respecto al espesor muscular, pico de torque, capacidad de trabajo y eco intensidad (p > 0,05). La fatiga general fue mayor tanto en el grupo ADT (p = 0,030) como en el grupo N-ADT (p = 0,047), cuando comparada al grupo CON. La fatiga física fue mayor en el grupo ADT que en el grupo CON (p = 0,006). Conclusión Los pacientes sometidos a la terapia de privación de andrógenos demostraron menores niveles de función muscular y mayores niveles de fatiga percibida que los individuos saludables del grupo control. Parece que la función muscular permanece menor en pacientes sometidos a ADT varios años después del inicio del tratamiento, lo que no ocurre con los pacientes N-ADT. Nivel de evidencia II; Estudios de diagnóstico - Investigación de un examen de diagnóstico.
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A better understanding of the relationship between osteoporosis and sarcopenia may help to develop effective preventive and therapeutic strategies. In the present study, the association between different stages of sarcopenia, BMD, and osteoporosis was examined. The salient findings indicate that a dose-response relationship exists between sarcopenia stages and bone-related phenotypes. PURPOSE: To assess the association between sarcopenia stages, bone mineral density (BMD), and the prevalence of osteoporosis in older women. METHODS: Two hundred thirty-four women (68.3 ± 6.3 years) underwent body composition and BMD measurements using dual-energy X-ray absorptiometry. Quadriceps isokinetic torque was evaluated, and the timed up-and-go test was conducted as a measure of function. Sarcopenia stages were classified according to European Working Group on Sarcopenia in Older People (EWGSOP): nonsarcopenia, presarcopenia, sarcopenia, and severe sarcopenia. Osteoporosis was defined as BMD value (hip or spine) 2.5 standard deviations below a young-adult reference population. Between-group differences were examined using ANOVA for continuous variables and chi-squared for categorical variables. Logistic regression was performed to evaluate the association between sarcopenia stages and osteoporosis. RESULTS: Rates of osteoporosis were 15.8%, 19.2%, 35.3%, and 46.2% for nonsarcopenia, presarcopenia, sarcopenia, and severe sarcopenia, respectively (P = 0.002). Whole-body and femoral neck BMD values were significantly lower among all sarcopenia stages when compared to nonsarcopenia (all P values < 0.05, η2p 0.113 to 0.109). The severe sarcopenia group also showed significantly lower lumbar spine BMD values and T-scores (both P values < 0.05; η2p 0.035 and 0.037, respectively). When clustered, sarcopenia and severe sarcopenia exhibited lower BMD values for all sites (all P values < 0.01), and presented a significantly higher risk for osteoporosis (odds ratio 3.445; 95% CI 1.521-7.844). CONCLUSION: The observed results provide support for the concept that a dose-response relationship exists between sarcopenia stages, BMD, and the presence of osteoporosis. These findings strengthen the clinical significance of the EWGSOP sarcopenia definition and indicate that severe sarcopenia should be viewed with attention by healthcare professionals.
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Densidade Óssea/fisiologia , Osteoporose/epidemiologia , Sarcopenia/fisiopatologia , Absorciometria de Fóton/métodos , Idoso , Idoso de 80 Anos ou mais , Composição Corporal/fisiologia , Doenças Ósseas Metabólicas/fisiopatologia , Feminino , Humanos , Modelos Logísticos , Vértebras Lombares/fisiopatologia , Osteoporose/etiologia , Prevalência , Sarcopenia/complicaçõesRESUMO
BACKGROUND AND PURPOSE: Lower-limb strength is required for everyday activities and thus its evaluation has been especially emphasized in older adults. Isokinetic testing is a criterion standard method to assess muscle strength; however, lack of reference values limits its usefulness in geriatric evaluation and rehabilitation. The aim of this study was to develop reference values of knee extensor isokinetic strength for older women. As a secondary aim, functional tests were performed for clinical significance validation. METHODS: A total of 453 older women aged 60 to 84 years participated in this study. Knee extensor isokinetic strength was measured using the Biodex System dynamometer at 60° per second. The Timed Up and Go test and the 5 times Sit-to-Stand test were used for functional performance evaluation. Participants were categorized into age groups of 5 years range. The 20th, 40th, 60th, and 80th percentiles were used for stratification purposes. RESULTS AND DISCUSSION: As expected, mean strength values significantly decreased with advancing age groups. Isokinetic percentile groups are presented according to age. Individuals in the lower percentile strata showed significantly reduced performance in both the Timed Up and Go and 5 times Sit-to-Stand tests (P < .05). CONCLUSION: This study provides normative values of isokinetic knee extensor strength in older women. The association between lower isokinetic knee extensor strength strata and reduced functional capacity supports the potential application of these reference values in clinical and research settings. Future studies should ascertain these findings in different female populations.
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Articulação do Joelho/fisiologia , Força Muscular/fisiologia , Músculo Esquelético/fisiologia , Fatores Etários , Idoso , Idoso de 80 Anos ou mais , Envelhecimento/fisiologia , Estudos Transversais , Feminino , Avaliação Geriátrica , Humanos , Extremidade Inferior/fisiologia , Pessoa de Meia-Idade , Dinamômetro de Força Muscular , Desempenho Físico Funcional , Equilíbrio Postural , Valores de ReferênciaRESUMO
A prática regular de exercícios físicos de diferentes naturezas tem sido amplamente recomendada para a população idosa, em virtude dos inúmeros benefícios relacionados à capacidade funcional e cognitiva nesta etapa da vida, aumentando a longevidade com independência funcional. Os efeitos da equoterapia na melhora do equilíbrio postural estão sendo cada vez mais estudados nas diversas populações, contudo, os estudos sobre esses efeitos em idosos são recentes. Dada a importância de melhorar a prática baseada em evidências, surgiu o interesse em realizar uma síntese rigorosa de todas as consultas relacionadas com o efeito da equoterapia no equilíbrio de idosos. Esta revisão seguiu as recomendações do Preferred reporting items for Systematic Reviews and Meta-análise (PRISMA) e registrado em um banco de dados internacional de revisões sistemáticas (PROSPERO). Foram selecionados artigos de bases de dados BIREME, SCIELO, MEDLINE CINAHAL, EBSCHOST e ISI, publicados em português e inglês. As palavras-chaves utilizadas foram: "equoterapia" OR "terapia assistida por animais" AND "equilíbrio postural" AND "idoso", presentes no título ou nos resumos dos artigos. Os artigos foram avaliados com base em seu nível de evidência e conduta. Utilizou-se a escala PEDro, para avaliação metodológica dos artigos incluídos na revisão. Identificou-se 20 estudos; 4 preencheram os critérios de inclusão. Estudos sobre os efeitos de equoterapia em idosos apresentam uma homogeneidade (I2 = 0 %) e uma melhora significativa (p = 0,001) equilíbrio. Embora os estudos apontem que a equoterapia seja benéfica para a melhora do equilíbrio postural, somente 4 estudos foram analisados, havendo necessidade de mais pesquisas que relacionem essas variáveis na população idosa....(AU)
The regular practice of physical exercises of diff erent natures has been widely recommended for the elderly population, due to the innumerable benefi ts related to functional and cognitive capacity in this stage of life, increasing the longevity with functional independence.The eff ects hippotherapy on the improvement of postural balance are being increasingly studied in diff erent populations, however, studies on these eff ects in the elderly are recent. Given the importance of improving evidence-based practice, the interest in performing a rigorous synthesis of all queries related to the eff ect of hippotherapy on balance postural. This review followed the reporting items Preferred recommendations for Systematic Reviews and Meta-analysis (PRISMA) And registered in an international database of systematic reviews (PROSPERO). Were selected articles from databases BIREME, SCIELO, MEDLINE CINAHAL, EBSCHOST e ISI, published Portuguese and English. The key words used were: hippotherapy, therapeutic riding, postural balance and elderly, present in the title or summary of articles. Were used the PEDro scale for methodological evaluation of the articles included in the review. It identifi ed 20 studies; 4 met the inclusion criteria. Studies on the eff ects of hippotherapy in older adults homogeneity (I2 = 0 %) and a signifi cant improvement (p = 0.001) in the functional capacity of the elderly. Although the studies indicate that hippotherapy is benefi cial for the improvement of postural balance, only 4 studies were analyzed, and there is a need for research that relates these variables to the elderly population....(AU)
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Humanos , Masculino , Feminino , Educação Física e Treinamento , Idoso , Terapia Assistida por CavalosRESUMO
Background/Study context: Falls represent the leading cause of accidental deaths in the elderly. Sarcopenia is a geriatric syndrome defined as the loss of muscle mass and strength. However, the association between falls and sarcopenia is still unclear. Thus, the aim of the present study was to investigate the association between different stages of sarcopenia and postural balance, risk of falls, and fear of falling in community-dwelling older women. METHODS: A total of 196 women (68.6 ± 6.5 years) underwent body composition (Dual-energy X-ray Absorptiometry), muscle strength (isokinetic), and functional (Timed Up-and-Go) assessments. Sarcopenia was classified according to European Working Group on Sarcopenia in Older People. Center of pressure (CoP) sway, risk, and fear of falling were assessed through force platform, QuickScreen, and Falls Efficacy Scale, respectively. ANOVA models and chi-squared were used to compare groups. RESULTS: Severe sarcopenic subjects presented higher risk of falling when compared to the other stages (p < 0.01). Regarding CoP sway, both mean speed and mediolateral range were significantly higher in severe sarcopenia when compared to both nonsarcopenia and presarcopenia (p < 0.05). Fear of falling was higher in all sarcopenia stages when compared to nonsarcopenic individuals (p < 0.05). CONCLUSION: Sarcopenia negatively affects balance, and both risk and fear of falling in community-dwelling older women. Moreover, this study provides evidence that sarcopenia severity is further associated to reduced balance and imposes an even greater risk of falls in the elderly.
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Acidentes por Quedas , Equilíbrio Postural , Sarcopenia/fisiopatologia , Fatores Etários , Idoso , Composição Corporal , Medo , Feminino , Humanos , Vida Independente , Atividade Motora , Força Muscular , Sarcopenia/psicologia , Fatores SexuaisRESUMO
The purpose of this study was to compare fatigue, strength, body composition, muscle thickness, and muscle quality between Hodgkin's lymphoma survivors (HLS) and apparently healthy subjects matched by age, gender, and physical activity levels (CON). Twelve HLS (32.16 ± 8.06) and 36 CON (32.42 ± 7.64) were enrolled in the study. Fatigue was assessed using the 20-item Multidimensional Fatigue Inventory, muscle strength using an isokinetic dynamometer, body composition using dual-energy X-ray absorptiometry, and thickness and muscle quality using B-mode ultrasound. Differences between HLS and CON were analyzed using independent samples t tests. No significant differences were observed between groups for any demographic characteristics: age ( P = .922), weight ( P = .943), height ( P = .511), body mass index ( P = .796), fat mass ( P = .688), fat-free mass ( P = .520), and percent body fat ( P = .446). No significant differences were observed for strength (peak torque; P = .552), relative peak torque ( P = .200), muscle thickness ( P > .05) and muscle quality ( P > .05). However, self-perceived fatigue was significantly higher in HLS than in CON ( P = .009). It appears that when HLS are matched by age and physical activity levels to CON, no significant difference in body composition, muscle thickness, muscle quality, or strength is observed. Self-perceived fatigue, as predicted, is higher in HLS, which may have implications and should be considered when prescribing exercise training to this cancer population.
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Fadiga/etiologia , Fadiga/fisiopatologia , Doença de Hodgkin/complicações , Doença de Hodgkin/fisiopatologia , Linfoma/complicações , Linfoma/fisiopatologia , Força Muscular/fisiologia , Adulto , Índice de Massa Corporal , Peso Corporal/fisiologia , Estudos de Casos e Controles , Exercício Físico/fisiologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Qualidade de Vida , Sobreviventes , Adulto JovemRESUMO
ABSTRACT Introduction: Pre-prandial exercise promotes greater mobilization of fat metabolism due to the increased release of catecholamines, cortisol, and glucagon. However, this response affects how the cardiovascular system responds to exercise. Objective: To evaluate the response of systolic, diastolic, and mean blood pressure, heart rate (HR) and rate-pressure product (RPP) to pre- and postprandial exercise. Methods: Ten physically active male subjects (25.50 ± 2.22 years) underwent two treadmill protocols (pre- and postprandial) performed for 36 minutes at 65% of VO2max on different days. On both days, subjects attended the laboratory on a 10-hour fasting state. For the postprandial session, volunteers ingested a pre-exercise meal of 349.17 kcal containing 59.3 g of carbohydrates (76.73%), 9.97 g of protein (12.90%), and 8.01 g of lipids (10.37%). Blood pressure, HR and RPP were measured before and after exercise. The 2x2 factorial Anova with the multiple comparisons test of Bonferroni was applied to analyze cardiovascular variables in both moments (pre- vs. postprandial). The significance level was set at p<0.05. Results: Systolic (121.70 ± 7.80 vs. 139.78 ± 12.91 mmHg) and diastolic blood pressure (66.40 ± 9.81 vs. 80.22 ± 8.68 mmHg) increased significantly after exercise only in the postprandial session (p<0.05). HR increased significantly (p<0.05) after both protocols (64.20 ± 15.87 vs. 141.20 ± 10.33 bpm pre-prandial and 63.60 ± 8.82 vs. 139.20 ± 10.82 bpm postprandial). RPP had a similar result (8052.10 ± 1790.68 vs. 18382.60 ± 2341.66 mmHg.bpm in the pre-prandial session and 7772.60 ± 1413.76 vs. 19564.60 ± 3128.99 mmHg.bpm in the postprandial session). Conclusion: These data suggest that fasted exercise does not significantly alter the blood pressure. Furthermore, the meal provided before the postprandial exercise may promote a greater blood pressure responsiveness during exercise.
RESUMO Introdução: O exercício pré-prandial promove maior mobilização do metabolismo de gordura devido ao aumento da liberação de catecolaminas, cortisol e glucagon. Contudo, tal resposta afeta a forma como o sistema cardiovascular responde ao exercício. Objetivo: Avaliar a resposta da pressão sistólica, diastólica e média, a frequência cardíaca (FC) e o duplo produto (DP) ao exercício pré e pós-prandial. Métodos: Dez indivíduos ativos (25,50 ± 2,22 anos) foram submetidos a dois protocolos de exercício em esteira (pré e pós-prandial) realizados durante 36 minutos a 65% do VO2máx em dias diferentes. Em ambos os dias, os indivíduos compareceram ao laboratório em jejum de 10 horas. Para a sessão pós-prandial, os voluntários ingeriram uma refeição pré-exercício de 349,17 kcal, contendo 59,3 g de carboidratos (76,73%), 9,97 g de proteína (12,90%) e 8,01 g de lipídeos (10,37%). A pressão sanguínea, a FC e o DP foram medidos antes e depois do exercício. A Anova fatorial (2 X 2) com as comparações múltiplas de Bonferroni foi aplicada para análise das variáveis nos dois momentos (pré e pós-prandial). O nível de significância foi fixado em p < 0,05. Resultados: A pressão sanguínea sistólica (121,70 ± 7,80 vs. 139,78 ± 12,91 mmHg) e a diastólica (66,40 ± 9,81 vs. 80,22 ± 8,68 mmHg) aumentaram significantemente após o exercício somente na sessão pós-prandial (p < 0,05). A FC aumentou significantemente (p < 0,05) após ambos os protocolos (64,20 ± 15,87 vs. 141,20 ± 10,33 bpm pré-prandial e 63,60 ± 8,82 vs. 139,20 ± 10,82 bpm pós-prandial). O DP teve resultado semelhante (8.052,10 ± 1.790,68 vs. 18.382,60 ± 2.341,66 mmHg.bpm na sessão pré-prandial e 7.772,60 ± 1.413,76 vs. 19.564,60 ± 3.128,99 mmHg.bpm na sessão pós-prandial). Conclusão: Esses dados sugerem que o exercício em jejum não altera significantemente a pressão sanguínea. Além disso, a refeição fornecida antes do exercício pós-prandial pode promover maior responsividade da pressão sanguínea durante o exercício.
RESUMEN Introducción: El ejercicio preprandial promueve una mayor movilización de metabolismo de la grasa debido al aumento de la liberación de catecolaminas, cortisol y glucagón. Sin embargo, tal respuesta afecta la forma en que el sistema cardiovascular responde al ejercicio. Objetivo: Evaluar la respuesta de la presión sistólica, diastólica y media, la frecuencia cardíaca (FC) y el doble-producto (DP) al ejercicio pre y postprandial. Métodos: Diez hombres activos (25,50 ± 2,22 años), fueron sometidos a dos protocolos de ejercicio en cinta rodante (pre y postprandial) realizados durante 36 minutos a 65% del VO2máx en días diferentes. En ambos días, los individuos asistieron al laboratorio después de un ayuno de 10 horas. Para la sesión postprandial, los voluntarios ingirieron una comida pre-ejercicio de 349,17 kcal, que contenía 59,3 g de hidratos de carbono (76,73%), 9,97 g de proteínas (12,90%) y 8,01 g de lípidos (10,37%). La presión sanguínea, la FC y el DP se midieron antes y después del ejercicio. Se aplicó el ANOVA factorial (2 x 2) con las comparaciones múltiples de Bonferroni para analizar las variables en los dos momentos (pre y postprandial). El nivel de significación se ha fijado en p < 0,05. Resultados: La presión sanguínea sistólica (121,70 ± 7,80 vs. 139,78 ± 12,91 mmHg) y la diastólica (66,40 ± 9,81 vs. 80,22 ± 8,68 mmHg) aumentaron significativamente después del ejercicio sólo en la sesión postprandial (p < 0,05). La FC aumentó significativamente (p < 0,05) después de ambos protocolos (64,20 ± 15,87 vs. 141,20 ± 10,33 lpm preprandial y 63,60 ± 8,82 vs. 139,20 ± 10,82 lpm postprandial). El DP tuvo un resultado similar (8.052,10 ± 1.790,68 vs. 18.382,60 ± 2.341,66 mmHg.lpm preprandial y 7.772,60 ± 1.413,76 vs. 19.564,60 ± 3.128.99 mmHg.lpm postprandial). Conclusión: Estos datos sugieren que el ejercicio en ayunas no altera significativamente la presión sanguínea. Además, la comida suministrada antes del ejercicio postprandial puede promover una mayor capacidad de respuesta de la presión sanguínea durante el ejercicio.
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Ageing is associated with changes in body composition that may result in sarcopenic obesity (SO). Interleukin-6 (IL-6) and C-reactive protein (CRP) are important inflammatory markers related to ageing. SO has been examined as an important public health problem, but its association with inflammatory markers has yet to be investigated. The aim of this study was to investigate the association between SO-related phenotypes and inflammatory markers in postmenopausal women. A total of 130 women (66·7 ± 5·2 years) underwent body composition evaluation using dual-energy X-ray absorptiometry. Volunteers were classified according to a SO definition previously described in the literature. Waist circumference (WC) and handgrip strength (HG) were also measured. Blood samples were collected for CRP, tumour necrosis factor and IL-6 measurements. All the inflammatory markers were higher in SO individuals when compared to non-SO; however, only IL-6 reached statistical significance (median 3·34 versus 1·37 pg ml-1 ; P<0·05). Also, CRP was significantly correlated (P<0·01) with body mass index (rs = 0·34), fat mass (FM; rs = 0·25) and WC (rs = 0·33). Similarly, IL-6 levels were significantly correlated (P<0·05) to age (rs = 0·19), FM (rs = 0·19) and WC (rs = 0·17). HG was found to be significantly reduced among subjects with higher IL-6 levels (P = 0·02). In summary, the combination of reduced muscle mass and excess body fat (i.e. SO) is associated with elevated inflammatory markers in postmenopausal women. Moreover, CRP and IL-6 are associated with SO-related phenotypes in this population.
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Mediadores da Inflamação/sangue , Inflamação/sangue , Obesidade/sangue , Pós-Menopausa/sangue , Sarcopenia/sangue , Absorciometria de Fóton , Adiposidade , Idoso , Biomarcadores/sangue , Proteína C-Reativa/análise , Estudos Transversais , Feminino , Força da Mão , Humanos , Inflamação/diagnóstico , Interleucina-6/sangue , Pessoa de Meia-Idade , Músculo Esquelético/fisiopatologia , Obesidade/diagnóstico , Obesidade/fisiopatologia , Fenótipo , Sarcopenia/diagnóstico , Sarcopenia/fisiopatologia , Fator de Necrose Tumoral alfa/sangue , Circunferência da CinturaRESUMO
BACKGROUND: Strength training post stroke is widely acknowledged as an important part of a rehabilitation program. Muscle strength has been shown to be a significant contributor to physical disability after stroke, which in turn has an immense impact on the reintegration of patients into society, affecting their quality of life. OBJECTIVE: This was a randomized intervention trial to determine the effect of a resistance training program on the quality of life in patients with stroke. METHODS: An experimental group (EG), consisting of 11 subjects aged 51.7 ± 8.0 years, and a control group (CG), consisting of 13 subjects aged 52.5 ± 7.7 years, were studied before and after 12 weeks. EG underwent 12 weeks of strength training three times a week. The CG did not undergo strength training during the 12-week study period. RESULTS: There was a significant increase in quality of life from pre-test to post-test (Δ% = 21.47%; p = 0.021) in EG. There were significant differences in all indicators of quality of life between groups at 12 weeks. There were greater gains in strength in EG than in CG (p ≤ 0.05). There was a negative correlation between the strength gains as determined with the 1RM test and the quality of life, especially in lower limb exercises. CONCLUSION: The results of this study indicate that there was an improvement in the measures of strength in EG, and that there was a correlation between improvements in strength and quality of life in these patients who had previously suffered a stroke at least one year prior to study.
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Isquemia Encefálica/complicações , Força Muscular/fisiologia , Qualidade de Vida , Treinamento Resistido/métodos , Reabilitação do Acidente Vascular Cerebral , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Acidente Vascular Cerebral/etiologia , Resultado do TratamentoRESUMO
BACKGROUND: The current recommendations on resistance training involving older adults have reported an improvement of body composition variables. Despite this, there is a lack of knowledge on how elastic resistance training (ERT) affects the muscle mass in older adults population. The purpose of this study was to determine the effects of a short-term ERT on muscle mass of health and untrained older adults. METHODS: Forty older adults were randomized into two groups of 20 individuals each: Control Group (CG = 66.2 ± 6.6 years) and Training Group (TG = 69.1 ± 6.3 years). TG underwent an ERT twice a week during 8 weeks and control group did not receive any specific intervention. The primary outcome was the upper and lower limbs muscle mass, measured by Dual-energy x-ray absorptiometry. The secondary outcomes were knee isokinetic peak torque (PT) at 60°/s and 120°/s speeds and isometric handgrip strength. A 2×2 mixed model (group [TG and CG] × time [pre and post]) analysis of variance (ANOVA) was applied to determine the effect on primary and secondary outcomes. RESULTS: The results of the ANOVA showed no significant effects in group x time interaction for (1) upper limbs fat free mass (F [1.38] = 1.80, p = 0.19, effect size [ES] = 0.1) and for (2) lower limbs fat free mass (F [1.38] = 0.03, p = 0.88, ES = 0.02). Regarding muscle strength, the ANOVA showed no significant effects in group x time interaction for (3) PT at 60°/s (F [1.38] = 0.33, p = 0.56, ES = 3.0), for (4) PT at 120°/s (F [1.38] = 0.80, p = 0.38, ES = 4.1) and for handgrip strength (F [1.38] = 0.65, p = 0.42-value, ES = 0.9). Analysis of PT in TG showed a significant change of 4.5%, but only at 120°/s (p = 0.01) when comparing pre and post-training (time interaction). CONCLUSIONS: Eight weeks of ERT did not show significant changes in muscle mass and strength of untrained older adults. TRIAL REGISTRATION: NCT02253615 (09/25/14).
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Composição Corporal , Extremidade Inferior , Força Muscular , Atrofia Muscular , Treinamento Resistido/métodos , Extremidade Superior , Absorciometria de Fóton/métodos , Idoso , Análise de Variância , Feminino , Humanos , Extremidade Inferior/diagnóstico por imagem , Extremidade Inferior/fisiopatologia , Masculino , Pessoa de Meia-Idade , Monitorização Fisiológica/métodos , Músculo Esquelético/fisiologia , Músculo Esquelético/fisiopatologia , Atrofia Muscular/diagnóstico , Atrofia Muscular/fisiopatologia , Atrofia Muscular/terapia , Resultado do Tratamento , Extremidade Superior/diagnóstico por imagem , Extremidade Superior/fisiopatologiaRESUMO
BACKGROUND: Osteopathic medicine is based on a diagnostic and therapeutic system to treat tissue mobility/ motility dysfunctions in general, using different approaches (depending on the target tissue) known as osteopathic manipulative treatment. Among the available techniques those ones addressed to the cranial field are the most questioned because of the lack of scientific evidence; but the compression of the 4th ventricle technique has been largely studied in clinical trials. Studies have shown that the technique may affect both central and autonomous nervous system, modulating some reflexes (Traube-Hering baro signal), and modifying brain cortex electrical activity through central sensitization in subjects with chronic low back pain. Thus, investigators hypothesize that the compression of the 4th ventricle may modulate peak alpha frequency (eletroencephalographic assessment) and promote physical relaxation in subjects in vigil. METHODS/DESIGN: A randomized, controlled crossover trial with blinded assessor was designed to test the hypothesis. A total of 81 participants will be assigned to three treatment conditions, with seven days of washout: (I) compression of the 4th ventricle; (II) sham compression of the fourth ventricle; (III) control (no intervention). The (I) power amplitude and the (II) frequencies of the dominant peak in the alpha band will be the primary outcome measures of the study. All participants will be recruited at the Outpatient Rehabilitation Service of the University Hospital of Brasília-University of Brasília. All the electroencephalographic exams will be conducted by a blinded assessor. DISCUSSION: The investigators hypothesize that patients with chronic low back pain submitted to the technique would have the peak alpha frequency modulated and, thus, would experience physical relaxation. TRIAL REGISTRATION: NCT02111382.
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Dor Lombar/terapia , Osteopatia , Adulto , Protocolos Clínicos , Estudos Cross-Over , Eletroencefalografia , Feminino , Cabeça/anatomia & histologia , Humanos , Masculino , Pessoa de Meia-Idade , Pacientes Ambulatoriais , Adulto JovemRESUMO
OBJECTIVE: To compare the clinical classification of the body mass index (BMI) and percentage body fat (PBF) for the prediction of inflammatory and atherogenic lipid profile risk in older women. METHOD: Cross-sectional analytical study with 277 elderly women from a local community in the Federal District, Brazil. PBF and fat-free mass (FFM) were determined by dual energy X-ray absorptiometry. The investigated inflammatory parameters were interleukin 6 and C-reactive protein. RESULTS: Twenty-five percent of the elderly women were classified as normal weight, 50% overweight, and 25% obese by the BMI. The obese group had higher levels of triglycerides and very low-density lipoproteins than did the normal weight group (P≤0.05) and lower levels of high-density lipoproteins (HDL) than did the overweight group (P≤0.05). According to the PBF, 49% of the elderly women were classified as eutrophic, 28% overweight, and 23% obese. In the binomial logistic regression analyses including age, FFM, and lipid profile, only FFM (odds ratio [OR]=0.809, 95% confidence interval [CI]: 0.739-0.886; P<0.0005) proved to be a predictor of reaching the eutrophic state by the BMI. When the cutoff points of PBF were used for the classification, FFM (OR=0.903, CI=0.884-0.965; P=0.003) and the total cholesterol/HDL ratio (OR=0.113, CI=0.023-0.546; P=0.007) proved to be predictors of reaching the eutrophic state. CONCLUSION: Accurate identification of obesity, systemic inflammation, and atherogenic lipid profile is key to assessing the risk of cardiometabolic diseases. Classification based on dual energy X-ray absorptiometry measures, along with biochemical and inflammatory parameters, seems to have a great clinical importance, since it allows the lipid profile eutrophic distinction in elderly overweight women.
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Adiposidade , Aterosclerose/fisiopatologia , Índice de Massa Corporal , Mediadores da Inflamação/sangue , Lipídeos/sangue , Absorciometria de Fóton , Fatores Etários , Idoso , Biomarcadores , Peso Corporal , Brasil , Proteína C-Reativa/análise , Estudos Transversais , Feminino , Humanos , Interleucina-6/sangue , SobrepesoRESUMO
The purpose of this study was to examine the association between sarcopenia and sarcopenic obesity (SO) with cardiometabolic risk factors in postmenopausal women. 149 volunteers (67.17±6.12 years) underwent body composition assessment using dual energy X-ray absorptiometry (DXA) and had analyzed blood samples collected for lipid profile, glucose metabolism and C-reactive protein (CRP). Sarcopenia was defined as an appendicular fat-free mass (AFFM) divided by height squared ≤5.45 kg/m(2) while SO was classified based on the residuals of a regression. Waist circumference (WC) and arterial blood pressure were also measured. Student's t-tests and correlations were used for analyses. Prevalence of sarcopenia and SO were respectively 16.8 and 21.5%. WC was significantly correlated with all the examined risk factors. AFFM relative to height squared was positively correlated with systolic blood pressure (SBP) and diastolic blood pressure (DBP), CRP, insulinaemia, HOMA score, and those classified as sarcopenic presented lower HOMA score when compared to nonsarcopenic. Regarding SO, although volunteers classified presented significantly higher fat mass (FM) and lower AFFM, it was not observed association with the examined risk factors. These findings support the association between WC and cardiometabolic risk factors in older women. In contrast, the approaches used to define sarcopenia and SO are not associated with cardiometabolic impairments.
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Avaliação Geriátrica , Obesidade/epidemiologia , Sarcopenia/epidemiologia , Absorciometria de Fóton , Idoso , Biomarcadores/sangue , Glicemia/análise , Determinação da Pressão Arterial , Composição Corporal , Proteína C-Reativa/metabolismo , Estudos Transversais , Feminino , Humanos , Lipídeos/sangue , Prevalência , Fatores de Risco , Circunferência da CinturaRESUMO
The purpose of this study was to investigate the association between the GHR exon 3 fl/d3 polymorphism and body composition traits in Brazilian cohorts of normal post-menarche adolescent girls and in post-menopausal women with and without osteoporosis. First, multiplex PCR and quantitative PCR (TaqMan) were used with 105 DNA samples from the general Brazilian population to validate the SNP rs6873545 as a surrogate marker for the GHR polymorphism. Subsequently, genotyping was carried out to evaluate associations for this polymorphism in 136 post-menarche adolescents and 175 post-menopausal women, who were evaluated for body composition traits such as bone mineral density and fat-free mass. Statistical analysis used an independent sample t test, one-way ANOVA test and post hoc Tukey HSD test. Significant values were assumed by p < 0.05. Genotyping indicated complete linkage disequilibrium between the GHR polymorphism and the SNP alleles (r(2) = 1.0). Adolescents and healthy post-menopausal women showed no genotype associations for body composition traits or osteoporosis. However, a lower total body bone mineral density was observed in fl/fl post-menopausal women with osteoporosis (p = 0.0004). These results suggest that the SNP rs6873545 can be used as a surrogate for the GHR fl/d3 polymorphism due to linkage disequilibrium in the Brazilian population and that the fl/fl genotype is a severity-related risk factor for osteoporosis, but did not appear to be associated with disease status.
Assuntos
Composição Corporal/genética , Densidade Óssea/genética , Osteoporose/genética , Receptores de Fatores de Crescimento/genética , Adolescente , Adulto , Idoso , Antropometria , Composição Corporal/fisiologia , Densidade Óssea/fisiologia , Brasil/epidemiologia , Proteínas de Transporte , Criança , Éxons/genética , Feminino , Genótipo , Humanos , Desequilíbrio de Ligação/genética , Masculino , Menarca/fisiologia , Menopausa/genética , Pessoa de Meia-Idade , Osteoporose/epidemiologia , Polimorfismo Genético/genética , Polimorfismo de Nucleotídeo Único/genética , Índice de Gravidade de Doença , Adulto JovemRESUMO
Aging produces several respiratory limitations and reduces tolerance to physical efforts, sometimes leading to pulmonary diseases in the elderly. The literature draws attention to the possible benefits of Yoga practice among the elderly, presenting evidence for significant improvements in quality of life. It was hypothesized that yoga practice can improve respiratory function in the elderly. The effects of a yoga program on pulmonary volumes and respiratory muscle strength were verified in 36 elderly women divided into a yoga group [YG] (63.1 ± 13.3 years of age) and a control group (61.0 ± 6.9 years of age). Maximal inspiratory and expiratory pressure (MIP and MEP) were assessed by a manovacuometer and tidal volume (VT), vital capacity (VC) and minute ventilation (VE) were measured by a ventilometer. The program comprised 65 min sessions, 3 times/week during 12 weeks. The heart rate and respiratory rate decreased significantly in the YG (76-39 ± 8-03 vs. 74-61±10.26 bpm and 18.61 ± 3.15 vs. 16.72 ± 3.12 resp/min, respectively). In the YG, VT and VE increased significantly (0.55 ± 0.22 vs. 0.64 ± 0.2 ml and 9.19 ± 2.39 vs. 10.05 ± 2.11 ml, respectively), as well as VC (1.48 ± 0.45 vs. 2.03 ± 0.72 ml). Improvements were also found in MIP and MEP in the YG (62.17 ± 14.77 vs. 73.06 ± 20.16 cmH2O and 80.56 ± 23.94 vs. 86.39 ± 20.16 cmH2O, respectively). It was concluded that a 12-week yoga program significantly improves pulmonary function of aged women.
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INTRODUÇÃO: Apesar do tremor, bradicinesia e rigidez serem os sintomas motores clássicos da doença de Parkinson (DP), a fraqueza muscular também tem sido apontada como um dos mais importantes sintomas motores associados a essa doença, porém, essa condição ainda é pouco estudada e os resultados são inconsistentes. OBJETIVOS: O presente estudo teve o propósito de comparar a força muscular do quadríceps entre indivíduos portadores de DP e indivíduos neurologicamente saudáveis pareados por idade e gênero. Foi comparada também a força muscular do membro mais acometido e menos acometido pela doença. MATERIAIS E MÉTODOS: Participaram deste estudo 26 voluntários, 13 do grupo Parkinson (GP: 64,08 ± 6,87 anos; 73,82 ± 13,03 Kg; 1,66 ± 0,07m;) e 13 do grupo controle (GC: 62,73 ± 6,42 anos; 79,46 ± 11,40 kg; 1,71 ± 0,07 m). Foi mensurado o pico de torque (PT) dos extensores do joelho por meio da dinamometria isocinética, na velocidade de 90º.s-1. Foi utilizado o teste t para comparar as médias intra e entre os grupos (p < 0,05). RESULTADOS: O PT absoluto foi significativamente menor no GP (119,29 ± 40,06 N.m) quando comparado ao GC (145,15 ± 20,05 N.m). Entre os indivíduos com DP, foram encontrados valores significativamente inferiores de força muscular do membro mais acometido quando comparado com o menos acometido (119,29± 40,06 N.m vs. 128,86 ± 35,56 N.m; p < 0,05). CONCLUSÃO: Com base nos resultados, conclui-se que portadores da DP apresentam reduzido PT isocinético dos extensores do joelho, sendo esses achados exacerbados no membro mais acometido pela doença.
INTRODUCTION: Despite the tremor, bradykinesia and rigidity are the classic motor symptoms of Parkinson's disease (PD), muscle weakness has also been pointed out as an important motor symptom associated to this disease, however this condition is still poorly studied and results are inconsistent. OBJECTIVES: This study aimed to compare quadriceps muscle strength between individuals with PD and neurologically healthy individuals matched for age and gender. We also compared muscle strength in the limb more and less affected by the disease. MATERIALS AND METHODS: This study had the participation of 26 volunteers: 13 from the Parkinson Group (64.08 ± 6.87 years, 73.82 ± 13.03 kg, 1.66 ± 0.07 m;) and 13 from the control group (62.73 ± 6.42 years, 79.46 ± 11.40 kg, 1.71 ± 0.07 m). Peak Torque (PT) was measured in knee extensors using an isokinetic dynamometer at a velocity of 90º.s -1. Student's t-test was used to compare average values intraand inter-groups (p < 0.05). RESULTS: Absolute PT was significantly lower in the Parkinson group (119.29 ± 40.06) when compared to the control group (145.15 ± 20.05 Nm). Among individuals with PD, we found significantly lower values of muscle strength in the more affected limb when compared to the less affected limb (119.29 ± 40.06 N.m vs 128.86 ± 35.56 N.m, P < 0.05). CONCLUSION: Based on the results, we concluded that patients with PD showed a decreased isokinetic PT in knee extensors, and these findings are exacerbated in the limb more affected by the disease.
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PURPOSE: To compare the metabolic parameters, flexibility, muscle strength, functional capacity, and lower limb muscle power of elderly women with and without the metabolic syndrome (MetS). METHODS: This cross-sectional study included 28 older women divided into two groups: with the MetS (n = 14; 67.3 ± 5.5 years; 67.5 ± 16.7 kg; 1.45 ± 0.35 m; 28.0 ± 7.6 kg/m(2)), and without the MetS (n = 14; 68.7 ± 5.3 years; 58.2 ± 9.9 kg; 1.55 ± 0.10 m; 24.3 ± 3.8 kg/m(2)). Body composition was evaluated by dual-energy X-ray absorptiometry and dynamic muscle strength was assessed by one-maximum repetition (1RM) tests in leg press, bench press and biceps curl exercises. Six-minute walk test, Timed Up and Go (TUG); 30-second sitting-rising; arm curl using a 2-kg dumbbell, sit-and-reach (flexibility), and vertical jump tests were performed. RESULTS: There was no difference between groups regarding age (P = 0.49), height (P = 0.46), body fat (%) (P = 0.19), systolic (P = 0.64), diastolic (P = 0.41) and mean blood pressure (P = 0.86), 30-second sitting-rising (P = 0.57), 30-s arm curl (P = 0.73), leg press 1RM (P = 0.51), bench press 1RM (P = 0.77), and biceps curl 1RM (P = 0.85). However, women without the MetS presented lower body mass (P = 0.001), body mass index (BMI) (P = 0.0001), waist circumference (P = 0.02), waist-to-height ratio (P = 0.02), fat body mass (kg) (P = 0.05), lean body mass (kg) (P = 0.02), blood glucose (P = 0.05), triglycerides (P = 0.03), Z-score for the MetS (P = 0.05), higher high-density lipoprotein-cholesterol (HDL-C) (P = 0.002), better performance on TUG (P = 0.01), flexibility (P = 0.03), six-minute walk test (P = 0.04), vertical jump (P = 0.05) and relative muscle strength for leg press (P = 0.03), bench press (P = 0.04) and biceps curl (P = 0.002) exercises as compared to women with the MetS. CONCLUSION: Elderly women with the MetS have higher metabolic risk profile and lower functional capacity, muscle strength, lower limb power and flexibility as compared to women without the MetS. The evaluation of functional capacity may help to determine the degree of physical decline in older persons with the MetS, while exercise interventions should be encouraged.
Assuntos
Síndrome Metabólica/fisiopatologia , Força Muscular/fisiologia , Aptidão Física/fisiologia , Absorciometria de Fóton , Idoso , Antropometria , Brasil , Estudos Transversais , Teste de Esforço/métodos , Feminino , Humanos , Pessoa de Meia-IdadeRESUMO
The objective of the study was to analyze the age marker in males and females as a predictor of the absence of frailty syndrome in the elderly. This was a cross-sectional study with 624 individuals. Receiver Operating Characteristic (ROC) curves were constructed and compared to areas of age, gender and absence of frailty. Cut-off points for age (years) were established to predict the absence of frailty (95% CI). The largest areas under the ROC curve for age were found for females. It was observed that the age of 72 years (women) or 67 (men) were the best cut-off points for predicting the absence of frailty. The age marker can serve as an important indicator in selecting priority groups for certain interventions.
O objetivo do estudo foi analisar o marcador etário, nos sexos feminino e masculino como preditor da ausência da síndrome de fragilidade em idosos, que se procedeu o estudo transversal com 624 indivíduos. Foram construídas curvas Receiver Operating Characteristic (ROC) e comparadas às áreas de idade, por sexo e a ausência da fragilidade. Identificaram-se pontos de corte de idade (anos) para predizer a ausência de fragilidade (IC 95%). Encontrou-se maior área sob a curva ROC para a idade no sexo feminino. Observou-se que a idade de 72 anos (mulheres) ou 67 anos (homens) foram os melhores pontos de corte para predizer a ausência de fragilidade. O marcador etário pode servir como importante indicador para seleção de grupos prioritários a determinadas intervenções.
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Humanos , Masculino , Feminino , Saúde do Idoso , Estudos Transversais , Curva ROC , Idoso FragilizadoRESUMO
O objetivo deste estudo foi comparar o consumo de oxigênio de pico (VO2pico) mensurado por meio de teste de esforço e os obtidos por equações preditivas. Participaram deste estudo 116 idosas (66,7 ± 5,8 anos), que realizaram teste ergoespirométrico em esteira. Os valores de VO2pico também foram estimados pela equação do Colégio Americano de Medicina do Esporte (ACSM) e equação de Foster. As comparações foram realizadas por meio da ANOVA para medidas repetidas. A relação entre valores da esteira e equações foi examinada pelo coeficiente de Pearson e método de Bland e Altman. As equações do ACSM e Foster superestimaram significantemente o VO2pico medido (p<0,001; diferença média de 6,9 e 2,7 ml.kg-1.min-1, respectivamente), sendo que a equação ACSM gerou valores superiores aos de Foster (p<0,05). Houve correlação positiva entre o valor do teste e o das equações (r=0,70; p<0,01), mas uma correlação negativa entre idade e VO2pico (r=-0,31; p=0,001). Os achados demonstram que para idosas, equações ergométricas comumente usadas superestimam o VO2pico em relação aos mensurados pela ergoespirometria, apontando para cautela quando da classificação da aptidão cardiorrespiratória por testes ergométricos.
The purpose of this study was to compare the peak oxygen uptake (VO2peak) measured through stress testing and those obtained by predictive equations. A total of 116 elderly women (mean age 66.7 ± 5.8 years) were submitted to a cardiopulmonary exercise test in treadmill (ramp protocol). In addition, VO2peak values were estimated through the American College of Sports Medicine (ACSM) and Foster equations. Measured and estimated values were compared using repeated measures ANOVA. Correlation between methods was examined using Pearson coefficient and agreement using Bland and Altman plot. Both ACSM and Foster equations significantly overestimated measured VO2peak (p<0.001; mean of 6.9 and 2.7 ml.kg-1.min-1, respectively). The ACSM equation generated greater values than the Foster equation. Positive and significant correlation was observed between measured and estimated values (r = 0.70; p<0.01), while age was negatively correlated with measured VO2peak (r = -0.31; p=0.001). Findings show that for the elderly, equations commonly used overestimate VO2peak measured by cardiopulmonary exercise test, pointing to caution during classification of cardiorespiratory fitness.