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Nat Prod Res ; 36(3): 765-771, 2022 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-32772561

RESUMO

Araticum is an edible and appreciable fruit of Annona coriacea, which is popularly known as a traditional herb in the Brazilian cerrado. A phytochemical study from the leaves of A. coriacea showed that HPLC-ESI-Q-Orbitrap® provided through PRM experiments (MS2) is an efficient method for the fast and accurate analysis of a complex mixture of annonaceous acetogenins, with the identification of sylvaticin and gigantetrocin-A type acetogenins for the first time. In addition, the crude leaf extract and acetogenin-rich fractions were assayed against Streptococcus mutans, S. mitis, S. sanguinis and S. salivarius strains, which are usually related to oral infections.


Assuntos
Acetogeninas , Annona , Acetogeninas/farmacologia , Antibacterianos/farmacologia , Cromatografia Líquida de Alta Pressão , Frutas
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