RESUMO
OBJECTIVE: We present a clinical case of inverted papilloma of the anterior urethra in a male patient. METHODS/RESULTS: 40 years-old man, without antecedents. The patient presented with dysuria and urethral bleeding on three occacions. Preliminary studies included radiographic voiding urethrocystography which revealed anterior urethral filling defect. Cystourethroscopy under anaesthetic was performed, allowing endoscopic resection of the tumour causing the filling defect. The Pathologic study of the resected specimen reported urethral inverted papilloma. CONCLUSIONS: Inverted papilloma located in the male urethra is rare. The most frequent clinical manifestations are dysuria and haematuria, although urethral bleeding may present when located in the anterior urethra. Diagnosis is based on clinical symptoms, ultrasound, endoscopy and mictional urethrocystography which allows detection of urethral filling defect. Treatment consists of transurethral resection of the lesion. Annual post-operative endoscopiy control is recommended.
Assuntos
Papiloma Invertido , Neoplasias Uretrais , Adulto , Humanos , Masculino , Papiloma Invertido/diagnóstico , Neoplasias Uretrais/diagnósticoRESUMO
OBJECTIVE: To report a case of prostate lymphoma and a brief review of the literature. METHODS/RESULTS: A 70 year-old mele patient was referred to the Urology departament with a clinical picture of prostatism, with acute urinary retention (AUR). Surgery with retropubic prostatectomy was performed, and pathology revealed a primary prostate lymphoma. The patient was referred to the departament of Oncology where he received polychemotherapy and radiotherapy. The patient is currently followed by regular visits to Urology outpatients service. The case study is followed by a brief bibliographic review, where we analyse clinical menifestations of this entity, complementary studies useful for diagnosis (laboratory test, trasrectal prostate biopsy, transuretral resection, ultrasound and computerised axial tomography), treatment options (surgery, polychemotherapy, radiotherapy) as well as survival in these patients. CONCLUSIONS: Of the cases reviewed, mean age at diagnosis was 57 years. Clinical debut was with prostate symptoms, with or without AUR and sometimes manifestations of renal failure due to obstructive uropathy, as well as general symptoms (astenia, anorexia, weight loss). PSA values remain unaltered in prostate lymphoma patients. Histologic diagnosis may be made by transrectal prostate biopsy, although transurethral resection (TUR) may be necessary for confirmation. Ultrasound and CT scan are of great utility for diagnosis of both local and distant tumors. From a therapeutic point of view, surgery for the obstruction of the lower urinary tract (TURP or retropubic prostatectomy) may be necessary, as well as the cyclophosphamide based polychemotherapy with corticosteroids and other cytostatic agents, and radiotherapy; intratecal chemotherapy has also been used adjuvant bone marrow transplantation.
Assuntos
Leucemia Linfocítica Crônica de Células B/patologia , Neoplasias da Próstata/patologia , Idoso , Humanos , MasculinoRESUMO
OBJECTIVES: We report a clinical case of inverted papilloma of the anterior male urethra. METHODS/RESULTS: 40-year-old male without significant past medical history presenting with dysuria and referring three episodes of urethral bleeding. Preliminary studies included voiding cystourethrogram (VCUG) which revealed a filling defect in the anterior urethra. Urethrocystoscopy was performed under anesthesia, with resection of the tumor. Pathologic study reported a urethral inverted papilloma. CONCLUSIONS: Inverted papillomas of the male urethra are rare. The most frequent clinical manifestations are dysuria and hematuria, although they may present with urethral bleeding when located in the anterior urethra. Diagnosis is based on clinical symptoms, ultrasound, endoscopy and VCUG which enable detection of urethral filling defects. The treatment of choice is transurethral resection of the lesion. Annual endoscopic control is recommended after surgery.