Assuntos
Adulto , Pessoa de Meia-Idade , Humanos , Masculino , Feminino , Peritonite/microbiologia , Ascite/complicações , Infecções Bacterianas , Cirrose Hepática/complicações , Peritonite/complicações , Peritonite/diagnóstico , Peritonite/mortalidade , Prognóstico , Recidiva , Chile , Taxa de Sobrevida , Estudos Prospectivos , Cirrose Hepática Alcoólica/complicaçõesRESUMO
We randomized 31 cirrhotic patients with tense ascites to a Group A receiving only diuretic therapy (spironolactone, furosemide, n = 14) or a Group B treated with paracentesis and intravenous albumin infusion (n = 17). Ascites was elminated in 88% of patients in Group B compared to 57% of patients in Group A (p < 0.05). Complications developed in 4 patients in Group A and 2 patients in Group B. Paracentesis was associated to a mild and transient reduction in mean arterial pressure and a significant rise in urinary output. Duration of hospital stay was 5 ñ 3 days in Group B and 22 ñ 6 Group A (p < 0.001). Survival and likelihood of rreadmission for ascites was similar in both groups. Our results suggest that paracentesis plus intravenous albumin infusion is a fast, safe and effective therapy for tense ascites in cirrhotic patients