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1.
J Appl Stat ; 51(1): 153-167, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38179162

RESUMO

A quick count seeks to estimate the voting trends of an election and communicate them to the population on the evening of the same day of the election. In quick counts, the sampling is based on a stratified design of polling stations. Voting information is gathered gradually, often with no guarantee of obtaining the complete sample or even information in all the strata. However, accurate interval estimates with partial information must be obtained. Furthermore, this becomes more challenging if the strata are additionally study domains. To produce partial estimates, two strategies are proposed: (1) a Bayesian model using a dynamic post-stratification strategy and a single imputation process defined after a thorough analysis of historic voting information; additionally, a credibility level correction is included to solve the underestimation of the variance and (2) a frequentist alternative that combines standard multiple imputation ideas with classic sampling techniques to obtain estimates under a missing information framework. Both solutions are illustrated and compared using information from the 2021 quick count. The aim was to estimate the composition of the Chamber of Deputies in Mexico.

2.
Lifetime Data Anal ; 28(2): 319-334, 2022 04.
Artigo em Inglês | MEDLINE | ID: mdl-35301665

RESUMO

In the study of life tables the random variable of interest is usually assumed discrete since mortality rates are studied for integer ages. In dynamic life tables a time domain is included to account for the evolution effect of the hazard rates in time. In this article we follow a survival analysis approach and use a nonparametric description of the hazard rates. We construct a discrete time stochastic processes that reflects dependence across age as well as in time. This process is used as a bayesian nonparametric prior distribution for the hazard rates for the study of evolutionary life tables. Prior properties of the process are studied and posterior distributions are derived. We present a simulation study, with the inclusion of right censored observations, as well as a real data analysis to show the performance of our model.


Assuntos
Teorema de Bayes , Simulação por Computador , Humanos , Tábuas de Vida , Processos Estocásticos , Análise de Sobrevida
3.
Biom J ; 62(5): 1245-1263, 2020 09.
Artigo em Inglês | MEDLINE | ID: mdl-32048325

RESUMO

To study the impact of climate variables on morbidity of some diseases in Mexico, we propose a spatiotemporal varying coefficients regression model. For that we introduce a new spatiotemporal-dependent process prior, in a Bayesian context, with identically distributed normal marginal distributions and joint multivariate normal distribution. We study its properties and characterise the dependence induced. Our results show that the effect of climate variables, on the incidence of specific diseases, is not constant across space and time and our proposed model is able to capture and quantify those changes.


Assuntos
Teorema de Bayes , Doença , Análise Espaço-Temporal , Clima , Humanos , Incidência , Distribuição Normal
4.
Biometrics ; 68(3): 859-68, 2012 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-22221181

RESUMO

Using a new type of array technology, the reverse phase protein array (RPPA), we measure time-course protein expression for a set of selected markers that are known to coregulate biological functions in a pathway structure. To accommodate the complex dependent nature of the data, including temporal correlation and pathway dependence for the protein markers, we propose a mixed effects model with temporal and protein-specific components. We develop a sequence of random probability measures (RPM) to account for the dependence in time of the protein expression measurements. Marginally, for each RPM we assume a Dirichlet process model. The dependence is introduced by defining multivariate beta distributions for the unnormalized weights of the stick-breaking representation. We also acknowledge the pathway dependence among proteins via a conditionally autoregressive model. Applying our model to the RPPA data, we reveal a pathway-dependent functional profile for the set of proteins as well as marginal expression profiles over time for individual markers.


Assuntos
Modelos Estatísticos , Análise Serial de Proteínas/estatística & dados numéricos , Proteômica/estatística & dados numéricos , Teorema de Bayes , Biomarcadores Tumorais/metabolismo , Biometria , Linhagem Celular Tumoral , Interpretação Estatística de Dados , Receptores ErbB/antagonistas & inibidores , Receptores ErbB/metabolismo , Feminino , Humanos , Lapatinib , Modelos Lineares , Cadeias de Markov , Método de Monte Carlo , Análise Multivariada , Neoplasias Ovarianas/tratamento farmacológico , Neoplasias Ovarianas/metabolismo , Quinazolinas/farmacologia , Transdução de Sinais/efeitos dos fármacos , Estatísticas não Paramétricas
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