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Future Microbiol ; 19(7): 577-584, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38884219

RESUMO

Aim: The objective of this study was to evaluate the clinical and epidemiological aspects of Candida infections. Methods: The study relied on the analysis of electronic medical records. Results: Among 183 patients with positive fungal infections, 57 were from the community and 126 from hospitals. Females predominated in both groups (82.4% in the community, 54.7% in hospitals). Non-albicans Candida spp. accounted for 62.8% of cases. Antifungal therapy was prescribed for 67 patients, with a 55.6% mortality rate. Conclusion: The increasing prevalence of non-albicans Candida species highlights the need for better candidiasis monitoring and control, especially concerning antifungal use amidst rising antimicrobial resistance, particularly in empirical therapy scenarios.


Fungal infections, particularly those caused by a group of yeasts called Candida, are a major concern. This study looks at clinical laboratory and medical records. We found that certain species of Candida not previously associated with human disease are common. We also noted the inappropriate use of antifungal medication, highlighting the need for healthcare workers to carefully diagnose patients and make appropriate decisions when treating fungal infections.


Assuntos
Antifúngicos , Candida , Candidíase , Farmacorresistência Fúngica , Humanos , Antifúngicos/uso terapêutico , Antifúngicos/farmacologia , Feminino , Masculino , Candida/efeitos dos fármacos , Candida/isolamento & purificação , Pessoa de Meia-Idade , Candidíase/epidemiologia , Candidíase/tratamento farmacológico , Candidíase/microbiologia , Candidíase/mortalidade , Idoso , Adulto , Idoso de 80 Anos ou mais , Prevalência , Adulto Jovem , Adolescente , Criança , Estudos Retrospectivos , Pré-Escolar
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