RESUMO
A case of congenital hepatic fibrosis in a 10-month-old calf is described. The calf had been raised in a feed lot for the past 173 days and exhibited loss of body condition and depression, followed by death. The most remarkable macroscopic lesions observed during necropsy were: jaundice, hepatomegaly with a multilobulated liver surface and diffuse pale brown colour of the parenchyma. Microscopically, the portal tracts were thickened and connected to each other by abundant fibrous tissue, delimiting irregular lobules of hepatocytes and occasional fibrosis of the central veins (perisinusoidal scars) and hyperplasia of embryonal bile ducts. Immunohistochemistry staining of the cytoplasm of the bile ducts was positive to AE1/AE3 and cell proliferation nuclear antigen (PCNA). The findings at necropsy, together with the results of the histopathological and immunohistochemistry studies, confirmed the diagnosis of congenital hepatic fibrosis.
Assuntos
Animais , Bovinos , Cirrose Hepática/congênito , Cirrose Hepática/diagnóstico , Cirrose Hepática/patologia , Cirrose Hepática/veterinária , AutopsiaRESUMO
A case of congenital hepatic fibrosis in a 10-month-old calf is described. The calf had been raised in a feed lot for the past 173 days and exhibited loss of body condition and depression, followed by death. The most remarkable macroscopic lesions observed during necropsy were: jaundice, hepatomegaly with a multilobulated liver surface and diffuse pale brown colour of the parenchyma. Microscopically, the portal tracts were thickened and connected to each other by abundant fibrous tissue, delimiting irregular lobules of hepatocytes and occasional fibrosis of the central veins (perisinusoidal scars) and hyperplasia of embryonal bile ducts. Immunohistochemistry staining of the cytoplasm of the bile ducts was positive to AE1/AE3 and cell proliferation nuclear antigen (PCNA). The findings at necropsy, together with the results of the histopathological and immunohistochemistry studies, confirmed the diagnosis of congenital hepatic fibrosis.(AU)
Assuntos
Animais , Bovinos , Cirrose Hepática/congênito , Cirrose Hepática/diagnóstico , Cirrose Hepática/patologia , Cirrose Hepática/veterinária , AutopsiaRESUMO
A free living female adult of Myrmecophaga tridactyla was captured in an area of deforestation in Salta Province of northwest Argentina, for subsequent relocation in Iberá Park. Three days after entering the quarantine it died with clinical signs of anorexia and ascites. It presented severe hypochromic microcytic anemia, hypoproteinemia and increase of CPK, AST and LDH on blood analysis. Grossly, there were ascites, hydrothorax, pulmonary congestion and severe catarrhal hyperplasic gastritis. The gastric mucosa was diffusely hyperemic with two clusters of numerous Physaloptera magnipapilla attached in the fundic region. Fundic mucosa was irregular with convoluted surface and covered with abundant brown-yellow catarrhal exudates. Microscopically, the gastric mucosa had well described punctate areas (pit-like structures) at points of P. magnipapilla attachment. Additionally, there were mucous hyperplasia of gastric glands and focal fibrosis with scarce infiltration of plasma cells, lymphocytes, multinucleated giant cells and eosinophils in the underlying lamina propria. This report describes a case of anemia and hyperplastic gastritis due to Physaloptera magnipapilla parasitism in a free-living Myrmecophaga tridactyla.(AU)
Assuntos
Animais , Feminino , Xenarthra/parasitologia , Gastrite/veterinária , Spiruroidea/parasitologia , Anemia Hipocrômica/veterinária , Argentina , Anorexia/veterinária , Ascite/veterináriaRESUMO
A free living female adult of Myrmecophaga tridactyla was captured in an area of deforestation in Salta Province of northwest Argentina, for subsequent relocation in Iberá Park. Three days after entering the quarantine it died with clinical signs of anorexia and ascites. It presented severe hypochromic microcytic anemia, hypoproteinemia and increase of CPK, AST and LDH on blood analysis. Grossly, there were ascites, hydrothorax, pulmonary congestion and severe catarrhal hyperplasic gastritis. The gastric mucosa was diffusely hyperemic with two clusters of numerous Physaloptera magnipapilla attached in the fundic region. Fundic mucosa was irregular with convoluted surface and covered with abundant brown-yellow catarrhal exudates. Microscopically, the gastric mucosa had well described punctate areas (pit-like structures) at points of P. magnipapilla attachment. Additionally, there were mucous hyperplasia of gastric glands and focal fibrosis with scarce infiltration of plasma cells, lymphocytes, multinucleated giant cells and eosinophils in the underlying lamina propria. This report describes a case of anemia and hyperplastic gastritis due to Physaloptera magnipapilla parasitism in a free-living Myrmecophaga tridactyla.
Assuntos
Feminino , Animais , Anemia Hipocrômica/veterinária , Gastrite/veterinária , Spiruroidea/parasitologia , Xenarthra/parasitologia , Anorexia/veterinária , Argentina , Ascite/veterináriaRESUMO
Eight of 57 water buffalo (Bubalus bubalis) died after grazing 30 days on 38-hectare pasture contaminated with Baccharis coridifolia in the north of the Province of Corrientes (northeastern Argentina). Most were found dead, others showed depression, anorexia, diarrhea, incoordination of movements and collision against fences. The conditions that caused the poisoning were overgrazing, poor pasture and lack of aversion to the consumption of Baccharis coridifolia. Gross findings included necrotic rumenitis, necrotic-hemorrhagic abomasitis, necrotic-hemorrhagic enteritis and marked brain edema. The histopathological findings were necrosis of the epithelium of the mucosa of the forestomachs, necrosis and hemorrhage in mucosa of the small intestine, necrosis of lymphocytes in lymph follicles in spleen and thymus and vasogenic brain edema. The lesions, except for brain edema, are typically reported in cattle intoxicated by Baccharis coridifolia. Vasogenic brain edema is not described in any animal species naturally or experimentally intoxicated with this plant; this change may be due to direct toxic effect of Baccharis coridifolia that cause vascular injury or was a secondary injury.
Assuntos
Animais , Baccharis/toxicidade , Búfalos , Edema Encefálico/veterinária , Plantas Tóxicas , Argentina , Intoxicação por Plantas/veterináriaRESUMO
Eight of 57 water buffalo (Bubalus bubalis) died after grazing 30 days on 38-hectare pasture contaminated with Baccharis coridifolia in the north of the Province of Corrientes (northeastern Argentina). Most were found dead, others showed depression, anorexia, diarrhea, incoordination of movements and collision against fences. The conditions that caused the poisoning were overgrazing, poor pasture and lack of aversion to the consumption of Baccharis coridifolia. Gross findings included necrotic rumenitis, necrotic-hemorrhagic abomasitis, necrotic-hemorrhagic enteritis and marked brain edema. The histopathological findings were necrosis of the epithelium of the mucosa of the forestomachs, necrosis and hemorrhage in mucosa of the small intestine, necrosis of lymphocytes in lymph follicles in spleen and thymus and vasogenic brain edema. The lesions, except for brain edema, are typically reported in cattle intoxicated by Baccharis coridifolia. Vasogenic brain edema is not described in any animal species naturally or experimentally intoxicated with this plant; this change may be due to direct toxic effect of Baccharis coridifolia that cause vascular injury or was a secondary injury.(AU)