RESUMO
Milk of calcium developed in 2 children with juvenile dermatomyositis. The fluid of the collection contained macrophages, interleukin-6, IL-1, and tumor necrosis factor. The patient who had dystrophic calcinosis had a dramatic improvement with the introduction of alendronate. These findings suggest that calcinosis of juvenile dermatomyositis may be mediated by activated macrophages and that alendronate can be an effective treatment for this condition.
Assuntos
Alendronato/uso terapêutico , Calcinose/tratamento farmacológico , Calcinose/etiologia , Dermatomiosite/complicações , Adolescente , Calcinose/metabolismo , Humanos , Interleucina-1/análise , Macrófagos , Masculino , Resultado do Tratamento , Fator de Necrose Tumoral alfa/análiseRESUMO
Tietze's syndrome, characterized by isolated swelling and tenderness of a costochondral junction, usually occurs in adults. We describe eight cases of Tietze's syndrome in children, four of them aged 1 year or less. The clinical aspects and laboratory and imaging findings should enable the clinician to recognize this benign entity, thereby avoiding invasive diagnostic procedures to rule out other conditions.
Assuntos
Síndrome de Tietze/diagnóstico , Criança , Pré-Escolar , Feminino , Humanos , Lactente , MasculinoRESUMO
Of 191 children who had had infantile seborrheic dermatitis, 88 were reexamined after 10 years. One child had psoriasis, four had atopic dermatitis, and seven had seborrheic dermatitis, which suggests a link with adult seborrheic dermatitis. A familial tendency toward infantile seborrheic dermatitis was noted, as was an increased incidence of allergy within the family.