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Rabbit farming is an activity with high growth potential due to its easy handling, high prolificacy, low polluting impact, and easy adaptability to family farming systems, producing meat of high biological value. Therefore, the aim of this work was to evaluate, using von Bertalanffy's nonlinear model, growth curves of weight as a function of age in 'Flemish Giant Rabbits' and 'New Zealand White' crossbred rabbits. Two different data collections were used: the longitudinal method and the cross-sectional method. The experiment was carried out at the Federal University of Lavras, located in the municipality of Lavras, Minas Gerais, Brazil, where 10 crossbred rabbits were evaluated, and animals were weighed from 0 to 150 days of age. Both methods proved to be adequate to describe the development of rabbits and the cross-sectional method proved to be an adequate alternative to obtention of growth curves, saving time in data collection and showing consistent estimates.

A cunicultura é uma atividade com alto potencial de crescimento devido à facilidade em seu manejo e à alta prolificidade, por apresentar baixo impacto poluidor, por se enquadrar bem em sistemas próprios de agricultura familiar, além de produzir carne de alto valor biológico. Diante disso, o objetivo deste trabalho foi avaliar, por meio do modelo não linear de von Bertalanffy, curvas de crescimento de coelhos mestiços de Gigante de Flandres e Nova Zelândia Branco, utilizando-se dois métodos distintos da coleta dos dados: o método longitudinal e o método transversal, a fim de estimar o crescimento do peso em função da idade. O experimento foi realizado na Universidade Federal de Lavras, situado no município de Lavras, Minas Gerais, Brasil. Foram avaliados 10 coelhos mestiços, cuja pesagem foi realizada de 0 a 150 dias de idade. Os dois métodos se mostraram adequados para descrever o crescimento de coelhos, e o método transversal se revelou uma boa alternativa, com ganho de tempo na coleta dos dados e apresentando estimativas consistentes.

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The objective was to evaluate the effect of dietary 25-hydroxycholecalciferol (25(OH)D3) or vitamin D3 (VitD3) and different total calcium (Ca) levels on the performance, carcass characteristics, blood, enzymatic, and bone biochemistry of broilers reared under heat stress between 1 and 42 days of age. A total of 504 male, Cobb 500, broiler chickens were distributed in a completely randomized design in a 2 × 4 factorial arrangement (VitD3 or 25(OH)D3 × four Ca levels (100, 90, 80 and 70% of the recommendations of Rostagno et al. (2011)), eight treatments, seven replicates and nine broilers per cage. Feed intake and feed conversion ratio did not (p>0.05) vary when levels of Ca were reduced and vitamin D3 sources were supplemented in the diets from 1 to 21 days for broilers chickens. 25 (OH)D3 increased weight gain results (p<0.05). From 1 to 42 d, no differences (p>0.05) were observed on performance, carcass yields and meat quality, bone deposition of Ca and P, and alkaline phosphatase concentration. Higher serum (p<0.05) concentrations of Ca and P were found in broilers fed with 25(OH)D3. The replacement of VitD3 with 25(OH)D3 and the Ca reduction of 30% in diets did not negatively affect performance, carcass characteristics, and Ca and P deposition in the tibia of broilers at 42 days of age, under heat stress.(AU)

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The pedigree file of the Boer and Nubian goat breeds in Mexico was constructed using the national database provided by the Asociación Mexicana de Criadores de Ganado Caprino de Registro. Field technicians routinely updated the goat national database by recording information from flocks participating in the performance-recording system. Information on animal identification number, parents, birth date, sex, breed, and farm of origin were used to undertake pedigree analyses using the ENDOG program (version 4.8). This paper presents a pedigree data file, tables and figures of characteristics of pedigree data, pedigree analyses, pedigree integrity, effective population size and genetic conservation index. The data can be used to estimate other population parameters, to monitor the genetic diversity of the Boer and Nubian goat breeds in Mexico, and also to design balanced breeding programs, maintaining genetic variation at reasonable levels and maximizing genetic progress in these populations.

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Although the metastasic breast cancer is still an incurable disease, recent advances have increased significantly the time to progression and the overall survival. However, too much information has been produced in the last 2 years, so a well-based guideline is a valuable document in treatment decision making. The SEOM guidelines are intended to make evidence-based recommendations on how to manage patients with advanced and recurrent breast cancer to achieve the best patient outcomes based on a rational use of the currently available therapies. To assign a level of certainty and a grade of recommendation the United States Preventive Services Task Force guidelines methodology was selected as reference.

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This experiment was conducted to evaluate the effects of dietary nitrogen-corrected apparent metabolizable energy (AMEn) levels on meat-type quail performance and carcass traits from 1 to 14d of age. A total of 1120 not sexed meat-type quails were randomly distributed to seven treatments, with eight replicates with 20 quails each. A basal corn and soybean meal-based diet was formulated to meet or exceed quail nutritional requirements, except for ME. Graded levels of soybean oil were added to the basal diet in replacement, to sand, to obtain dietary treatments (2,600; 2,700; 2,800; 2,900; 3,000; 3,100 and 3,200 KcalAMEn/kg diet). Data were analyzed as one-way ANOVA and optimum AMEn levels were estimated using polynomial regression model. Increasing in dietary AMEn levels elicited a linear decrease (p<0.01) in feed intake and nutrient intake (AMEn, protein and lysine). Quail weight gain and final body weight exhibited a quadratic response (p<0.03) to increased AMEn levels, being both optimized at 2820 KcalAMEn/kg diet. Graded AMEn levels elicited a linear increase (p<0.01) in carcass dry matter and fat content, whereas moisture content was linearly decreased (p<0.01). The protein content of the carcasses was not influenced (p>0.05) by AMEn. Based on the results, the dietary AMEn level that warrants adequate performance and carcass traits of meat-type quails from 1 to 14d of age is 2,820 Kcal/kg diet.(AU)

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This study was conducted to determine the optimal standardized ileal digestible arginine to lysine (SID Arg:Lys) ratio for Japanese quails in the egg-laying phase. A total of two hundred forty-five 35-week-old Japanese quails (181 ± 1.30 g initial body weight) were randomly assigned to five treatment groups with seven replicates of seven quails. Graded levels of L-Arginine were added to a basal diet in order to produce five SID Arg:Lys ratios (101, 106, 111, 116 and 121%). Collected data were analyzed as one-way ANOVA and optimal ratio was estimated using polynomial regression model (linear and quadratic) based on performance traits. Statistical differences were considered for p<0.05. Graded SID Arg:Lys ratios did not affect performance traits assessed. Based on results, the SID Arg:Lys ratio of 101% is sufficient to warrant proper performance of Japanese quails in the egg-laying phase.(AU)

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This study was conducted to determine the optimal standardized ileal digestible arginine to lysine (SID Arg:Lys) ratio for Japanese quails in the egg-laying phase. A total of two hundred forty-five 35-week-old Japanese quails (181 ± 1.30 g initial body weight) were randomly assigned to five treatment groups with seven replicates of seven quails. Graded levels of L-Arginine were added to a basal diet in order to produce five SID Arg:Lys ratios (101, 106, 111, 116 and 121%). Collected data were analyzed as one-way ANOVA and optimal ratio was estimated using polynomial regression model (linear and quadratic) based on performance traits. Statistical differences were considered for p<0.05. Graded SID Arg:Lys ratios did not affect performance traits assessed. Based on results, the SID Arg:Lys ratio of 101% is sufficient to warrant proper performance of Japanese quails in the egg-laying phase.

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This experiment was conducted to evaluate the effects of dietary nitrogen-corrected apparent metabolizable energy (AMEn) levels on meat-type quail performance and carcass traits from 1 to 14d of age. A total of 1120 not sexed meat-type quails were randomly distributed to seven treatments, with eight replicates with 20 quails each. A basal corn and soybean meal-based diet was formulated to meet or exceed quail nutritional requirements, except for ME. Graded levels of soybean oil were added to the basal diet in replacement, to sand, to obtain dietary treatments (2,600; 2,700; 2,800; 2,900; 3,000; 3,100 and 3,200 KcalAMEn/kg diet). Data were analyzed as one-way ANOVA and optimum AMEn levels were estimated using polynomial regression model. Increasing in dietary AMEn levels elicited a linear decrease (p0.05) by AMEn. Based on the results, the dietary AMEn level that warrants adequate performance and carcass traits of meat-type quails from 1 to 14d of age is 2,820 Kcal/kg diet.

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Objetivou-se, com este estudo, avaliar o ajuste dos modelos de Brody, Gompertz, Logístico e Von Bertalanffy aos dados de altura na cernelha de equinos Mangalarga Marchador, ponderando pelo inverso da variância, a fim de selecionar o melhor modelo e predizer sobre o crescimento e a maturidade dos animais dessa raça. Foram utilizados dados de 230 equinos dos seis aos 176 meses de idade, os quais foram divididos por sexo e em 16 classes de idade. Os modelos estudados foram comparados segundo os avaliadores de qualidade: coeficiente de determinação (R2); desvio padrão residual (DPR) e critério de informação de Akaike (AIC). A estimação dos parâmetros dos modelos foi realizada pelo método de mínimos quadrados ponderado no software R. Todos os modelos avaliados se mostraram adequados para descrever a curva de crescimento em ambos os sexos. Perante os avaliadores utilizados, o modelo Logístico foi o mais adequado para descrever as curvas de crescimento em altura na cernelha nos dois sexos da raça Mangalarga Marchador. Observou-se também um crescimento acelerado nos primeiros meses de idade. Os animais machos atingiram uma altura adulta maior, porém as fêmeas são mais precoces, pois apresentaram maior estimativa para o índice de maturidade.(AU)

This work aimed to evaluate the fit of models Brody, Gompertz, Logistic and Von Bertalanffy to height at the withers of Mangalarga Marchador horses, weighed by the inverse of variance, in order to select the best model and predict growth and maturity of this breed pf animals. We used data of 230 equines from 06 to 176 months of age who were divided by sex and 16 age classes. The models were compared according to the quality assessors: coefficient of determination (R2); residual standard deviation (RSD) and Akaike information criteria (AIC). The estimation of the parameters from models was performed by the weighted least squares method in Software R. All models evaluated were suitable to describe the growth curve in both sexes. In view of the evaluators used, the logistic model was the most suitable to describe the growth curves in withers height in both sexes for the race Mangalarga Marchador. A strong growth at first age was also observed. The males reached a greater adult height, but females did so sooner, because they presented higher estimates for the maturity index.(AU)

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Objetivou-se, com este estudo, avaliar o ajuste dos modelos de Brody, Gompertz, Logístico e Von Bertalanffy aos dados de altura na cernelha de equinos Mangalarga Marchador, ponderando pelo inverso da variância, a fim de selecionar o melhor modelo e predizer sobre o crescimento e a maturidade dos animais dessa raça. Foram utilizados dados de 230 equinos dos seis aos 176 meses de idade, os quais foram divididos por sexo e em 16 classes de idade. Os modelos estudados foram comparados segundo os avaliadores de qualidade: coeficiente de determinação (R2); desvio padrão residual (DPR) e critério de informação de Akaike (AIC). A estimação dos parâmetros dos modelos foi realizada pelo método de mínimos quadrados ponderado no software R. Todos os modelos avaliados se mostraram adequados para descrever a curva de crescimento em ambos os sexos. Perante os avaliadores utilizados, o modelo Logístico foi o mais adequado para descrever as curvas de crescimento em altura na cernelha nos dois sexos da raça Mangalarga Marchador. Observou-se também um crescimento acelerado nos primeiros meses de idade. Os animais machos atingiram uma altura adulta maior, porém as fêmeas são mais precoces, pois apresentaram maior estimativa para o índice de maturidade.(AU)

This work aimed to evaluate the fit of models Brody, Gompertz, Logistic and Von Bertalanffy to height at the withers of Mangalarga Marchador horses, weighed by the inverse of variance, in order to select the best model and predict growth and maturity of this breed pf animals. We used data of 230 equines from 06 to 176 months of age who were divided by sex and 16 age classes. The models were compared according to the quality assessors: coefficient of determination (R2); residual standard deviation (RSD) and Akaike information criteria (AIC). The estimation of the parameters from models was performed by the weighted least squares method in Software R. All models evaluated were suitable to describe the growth curve in both sexes. In view of the evaluators used, the logistic model was the most suitable to describe the growth curves in withers height in both sexes for the race Mangalarga Marchador. A strong growth at first age was also observed. The males reached a greater adult height, but females did so sooner, because they presented higher estimates for the maturity index.(AU)

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Arginase 1 (ARG1) and arginase 2 (ARG2) compete with nitric oxide synthases for the substrate l-arginine. Here we aim to assess whether arginase 1 and 2 plasma levels, plasma arginase activity or genetic factors are associated with altered responsiveness to sildenafil. We studied 71 post-prostatectomy erectile dysfunction (ED) patients (PED group) and 72 clinical ED patients (CED). Patients responded to the International Index of Erectile Function questionnaire before and after the treatment. We found positive and negative correlations between plasma levels of arginase 1 and sildenafil responsiveness in the PED and CED groups, respectively. PED group also presented negative correlation between plasma arginase activity and sildenafil responsiveness. Sildenafil poor responders have shown higher plasma arginase activity in PED and higher arginase 1 levels on CED groups. In addition, variant genotypes for the rs2781659, rs2781667 and rs17599586 polymorphisms were associated with reduced arginase activity, as well as the GTTT ARG1 haplotype in CED group.

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ABSTRACT This study was conducted to determine the optimum standardized ileal digestible isoleucine to lysine (SID Ile:Lys) ratio for meat-type quails from 15 to 35 d of age. Three hundred fifty not-sexed meat-type quails (Coturnix coturnix coturnix) were randomly assigned into five treatments, with seven replicates of 10 quails each. An isoleucine-deficient corn-soybean meal-based diet was formulated and graded supplemented with L-isoleucine (99%) to obtain diets containing SID Ile:Lys ratios of 55,61, 67, 73, and 79%. Data were analyzed as one-way ANOVA and optimum SID Ile:Lys was estimated by polynomial (linear and quadratic) regression. Statistical differences were considered when p 0.05. Quail performance from 15 and 21 d and 15 and 28 d of age was not affected by the treatments. From 15 to 35 d of age, body weight gain and body weight exhibited a quadratic response to increasing dietary SID Ile:Lys ratios, and were optimized at 66 and 67% SID Ile:Lys, respectively. Feed conversion ratio was not influenced by SID Ile:Lys ratios in any of the phases assessed herein. Based on the results, the optimum SID Ile:Lys ratio for meat-type quails from 15 to 35 d of age is 67%.(AU)

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ABSTRACT This study was conducted to determine the optimum standardized ileal digestible isoleucine to lysine (SID Ile:Lys) ratio for meat-type quails from 15 to 35 d of age. Three hundred fifty not-sexed meat-type quails (Coturnix coturnix coturnix) were randomly assigned into five treatments, with seven replicates of 10 quails each. An isoleucine-deficient corn-soybean meal-based diet was formulated and graded supplemented with L-isoleucine (99%) to obtain diets containing SID Ile:Lys ratios of 55,61, 67, 73, and 79%. Data were analyzed as one-way ANOVA and optimum SID Ile:Lys was estimated by polynomial (linear and quadratic) regression. Statistical differences were considered when p 0.05. Quail performance from 15 and 21 d and 15 and 28 d of age was not affected by the treatments. From 15 to 35 d of age, body weight gain and body weight exhibited a quadratic response to increasing dietary SID Ile:Lys ratios, and were optimized at 66 and 67% SID Ile:Lys, respectively. Feed conversion ratio was not influenced by SID Ile:Lys ratios in any of the phases assessed herein. Based on the results, the optimum SID Ile:Lys ratio for meat-type quails from 15 to 35 d of age is 67%.

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Metastatic breast cancer is a heterogeneous disease that presents in varying forms, and a growing number of therapeutic options makes it difficult to determine the best choice in each particular situation. When selecting a systemic treatment, it is important to consider the medication administered in the previous stages, such as acquired resistance, type of progression, time to relapse, tumor aggressiveness, age, comorbidities, pre- and post-menopausal status, and patient preferences. Moreover, tumor genomic signatures can identify different subtypes, which can be used to create patient profiles and design specific therapies. However, there is no consensus regarding the best treatment sequence for each subgroup of patients. During the SABCC Congress of 2014, specialized breast cancer oncologists from referral hospitals in Europe met to define patient profiles and to determine specific treatment sequences for each one. Conclusions were then debated in a final meeting in which a relative degree of consensus for each treatment sequence was established. Four patient profiles were defined according to established breast cancer phenotypes: pre-menopausal patients with luminal subtype, post-menopausal patients with luminal subtype, patients with triple-negative subtype, and patients with HER2-positive subtype. A treatment sequence was then defined, consisting of hormonal therapy with tamoxifen, aromatase inhibitors, fulvestrant, and mTOR inhibitors for pre- and post-menopausal patien ts; a chemotherapy sequence for the first, second, and further lines for luminal and triple-negative patients; and an optimal sequence for treatment with new antiHER2 therapies. Finally, a document detailing all treatment sequences, that had the agreement of all the oncologists, was drawn up as a guideline and advocacy tool for professionals treating patients with this disease.

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This trial was performed to determine the ideal ratio of digestible methionine + cysteine (Met/Lys) with digestible lysine for meat-type quails from 1 to 14 days of age. A total of six hundred thirty, one-day-old, not sexed meat type quails were randomly assigned to six groups of treatments, each one with seven replicates and fifteen quails per experimental unit. A basal diet, methionine + cysteine-deficient, was graded supplemented with DL-Methionine (0.108; 0.169; 0.230; 0.291; 0.352 and 0.413%) to obtain the treatments, represented by six digestible Met/Lys ratios (0.60; 0.65; 0.70; 0.75; 0.80 and 0.85). Data was analyzed using ANOVA and polynomial regression and broken-line models were used to estimate the digestible Met/Lys ideal ratio, considering adjust of data to both models. Statistical significance was considered when p0.05. Feed intake, weight gain and final body weight was linearly increased as dig. Met/Lys ratio increased. Feeding conversion was improved with increasing in dig. Met/Lys ratios. A quadratic response on feathering percentage was observed with increasing dig. Met/Lys ratios. Digestible Met/Lys ratio which, maximized feathering percentage in meat-type quails, was 0.74. According to linear broken-line model, dig. Met/Lys ratio estimated for optimum feed intake, weight gain, final body weight and feeding conversion were, respectively, 0.66; 0.71; 0.71 and 0.74. The dig. Met/Lys ideal ratio for meat-type quails from one to 14 days of age is 0.74.(AU)

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This study was conducted to estimate the dig. valine to lysine (Val:Lys) ideal ratio for meat-type quails from 15 to 35 d of age. A total of 385, 15-day-old not sexed quails, were randomly assigned to five treatments, each one seven times replicated with eleven quails per experimental unit. Experimental treatments consisted of five dig. Val:Lys ratios (0.65; 0.70; 0.75; 0.80 and 0.85). Ideal dig. Val:Lys ratio was estimated using polynomial regression and linear broken-line regression model. Significant effect was considered when p0.05. Feed conversion ratio was not affected by dig. Val:Lys ratios in any of the assessed phases. From 15 to 21 d of age Val:Lys ratios increased linearly feed intake, weight gain and body weight. From 15 to 28 d of age, weight gain and body weight were both optimized by the Val:Lys ratio of 0.77. A linear effect of dig. Val:Lys ratios was observed on weight gain and final body weight from 15 to 35 d of age. From 15 to 35 d of age, according to linear broken-line regression model, the dig. Val:Lys ideal ratios for optimum final body weight and weight gain were 0.77 and 0.76, respectively. Based on the results the estimated dig. Val:Lys ratio for optimum meat-type quail performance from 15 to 35 d of age is 0.77(AU)

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This trial was performed to determine the ideal ratio of digestible methionine + cysteine (Met/Lys) with digestible lysine for meat-type quails from 1 to 14 days of age. A total of six hundred thirty, one-day-old, not sexed meat type quails were randomly assigned to six groups of treatments, each one with seven replicates and fifteen quails per experimental unit. A basal diet, methionine + cysteine-deficient, was graded supplemented with DL-Methionine (0.108; 0.169; 0.230; 0.291; 0.352 and 0.413%) to obtain the treatments, represented by six digestible Met/Lys ratios (0.60; 0.65; 0.70; 0.75; 0.80 and 0.85). Data was analyzed using ANOVA and polynomial regression and broken-line models were used to estimate the digestible Met/Lys ideal ratio, considering adjust of data to both models. Statistical significance was considered when p0.05. Feed intake, weight gain and final body weight was linearly increased as dig. Met/Lys ratio increased. Feeding conversion was improved with increasing in dig. Met/Lys ratios. A quadratic response on feathering percentage was observed with increasing dig. Met/Lys ratios. Digestible Met/Lys ratio which, maximized feathering percentage in meat-type quails, was 0.74. According to linear broken-line model, dig. Met/Lys ratio estimated for optimum feed intake, weight gain, final body weight and feeding conversion were, respectively, 0.66; 0.71; 0.71 and 0.74. The dig. Met/Lys ideal ratio for meat-type quails from one to 14 days of age is 0.74.

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This study was conducted to estimate the dig. valine to lysine (Val:Lys) ideal ratio for meat-type quails from 15 to 35 d of age. A total of 385, 15-day-old not sexed quails, were randomly assigned to five treatments, each one seven times replicated with eleven quails per experimental unit. Experimental treatments consisted of five dig. Val:Lys ratios (0.65; 0.70; 0.75; 0.80 and 0.85). Ideal dig. Val:Lys ratio was estimated using polynomial regression and linear broken-line regression model. Significant effect was considered when p0.05. Feed conversion ratio was not affected by dig. Val:Lys ratios in any of the assessed phases. From 15 to 21 d of age Val:Lys ratios increased linearly feed intake, weight gain and body weight. From 15 to 28 d of age, weight gain and body weight were both optimized by the Val:Lys ratio of 0.77. A linear effect of dig. Val:Lys ratios was observed on weight gain and final body weight from 15 to 35 d of age. From 15 to 35 d of age, according to linear broken-line regression model, the dig. Val:Lys ideal ratios for optimum final body weight and weight gain were 0.77 and 0.76, respectively. Based on the results the estimated dig. Val:Lys ratio for optimum meat-type quail performance from 15 to 35 d of age is 0.77

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Calcium (Ca) and available phosphorus (avP) requirements for egg production are different between the beginning and the end of the egg-production cycle. The objective of this study was to estimate the Ca and avP requirements of Japanese quails at end of the production phase. In total, 256 Japanese quails with 48 weeks of age were randomly distributed in 2 x 2 factorial arrangement consisting of two Ca levels (29 and 38 g/kg) and two avP levels (1.5 and 3.0 g/kg), totaling four treatments with eight replicates of eight hens each. The variables evaluated were feed intake (FI); egg production (EP); marketable egg production (MEP); egg weight (EW); egg mass (EM); feed conversion ratio per egg mass (FCRM); feed conversion ratio per dozen eggs (FCRD); livability (L); yolk weight (YW), albumen weight (AW), eggshell weight (SW); yolk percentage (YP), albumen percentage (AP), eggshell percentage (SP), specific egg weight (SEW); bone calcium percentage (BCa), bone phosphorus percentage (BP), bone ash weight (Bash) and bone ash percentage (PBash). There was no interaction between Ca and avP levels for any of the evaluated parameters, except for SEW. Quail performance was not influenced by the treatments, except for MEP. Bone characteristics were not influenced by the tested dietary Ca and avP levels. However, SW and SP increased and AP decreased as dietary Ca level increased. The dietary supplementation of 38 g Ca/kg and 3.0 g avP/kg may increase marketable egg production and the egg quality of Japanese quails at end of the production cycle.(AU)

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Calcium (Ca) and available phosphorus (avP) requirements for egg production are different between the beginning and the end of the egg-production cycle. The objective of this study was to estimate the Ca and avP requirements of Japanese quails at end of the production phase. In total, 256 Japanese quails with 48 weeks of age were randomly distributed in 2 x 2 factorial arrangement consisting of two Ca levels (29 and 38 g/kg) and two avP levels (1.5 and 3.0 g/kg), totaling four treatments with eight replicates of eight hens each. The variables evaluated were feed intake (FI); egg production (EP); marketable egg production (MEP); egg weight (EW); egg mass (EM); feed conversion ratio per egg mass (FCRM); feed conversion ratio per dozen eggs (FCRD); livability (L); yolk weight (YW), albumen weight (AW), eggshell weight (SW); yolk percentage (YP), albumen percentage (AP), eggshell percentage (SP), specific egg weight (SEW); bone calcium percentage (BCa), bone phosphorus percentage (BP), bone ash weight (Bash) and bone ash percentage (PBash). There was no interaction between Ca and avP levels for any of the evaluated parameters, except for SEW. Quail performance was not influenced by the treatments, except for MEP. Bone characteristics were not influenced by the tested dietary Ca and avP levels. However, SW and SP increased and AP decreased as dietary Ca level increased. The dietary supplementation of 38 g Ca/kg and 3.0 g avP/kg may increase marketable egg production and the egg quality of Japanese quails at end of the production cycle.

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