Assuntos
Carcinoma Basocelular/diagnóstico , Neoplasias Primárias Múltiplas/diagnóstico , Nevo/diagnóstico , Neoplasias Cutâneas/diagnóstico , Adulto , Carcinoma Basocelular/patologia , Dermoscopia , Feminino , Humanos , Microscopia Confocal , Neoplasias Primárias Múltiplas/patologia , Nevo/patologia , Neoplasias Cutâneas/patologiaRESUMO
Superficial angiomyxomas (SA) of the skin are rare benign cutaneous tumors of soft tissue composed of prominent myxoid matrix and numerous blood vessels. SA are more common in males [1] and they are usually located on the trunk but can also appear on the lower limbs, head, neck and genitalia [2,3]. Treatment is surgical, the total excision is curative, but local recurrence is possible [4]. Herein we present a 72-year-old patient with a history of melanoma in situ, with a new lesion on the lower back.
Assuntos
Hipopigmentação/patologia , Nevo Pigmentado/patologia , Neoplasias Cutâneas/patologia , Adulto , Biópsia por Agulha , Dermoscopia/métodos , Diagnóstico Diferencial , Feminino , Humanos , Hipopigmentação/diagnóstico , Imuno-Histoquímica , Masculino , Microscopia Confocal/métodos , Pessoa de Meia-Idade , Nevo Pigmentado/diagnóstico , Estudos de Amostragem , Neoplasias Cutâneas/diagnósticoAssuntos
Carcinoma de Células Renais/secundário , Dermoscopia , Neoplasias Faciais/secundário , Neoplasias Renais/patologia , Neoplasias Cutâneas/secundário , Idoso , Carcinoma de Células Renais/patologia , Bochecha , Neoplasias Faciais/patologia , Humanos , Masculino , Neoplasias Cutâneas/patologiaRESUMO
Basal cell naevus syndrome is an inherited autosomal dominant genetic disorder characterised by multiple basal cell carcinomas (BCC), skeletal, neurological and opthalmological abnormalities. The treatment of choice of the often multiple and large BCC consists of a combined approach including surgery, liquid nitrogen and other topical treatment modalities. Imiquimod 5% cream is an immune-response-modifying drug with antiviral and anti-tumour activity. Recent reports have associated the immune-stimulant properties of imiquimod with the exacerbation of several autoimmune skin diseases, such as eczema, psoriasis, vitiligo and lichenoid dermatitis. Here we report a patient with basal cell naevus syndrome who developed a lichen planopilaris on the same site of the scalp, which had been previously treated with two cycles of imiquimod for multiple BCC.
Assuntos
Alopecia/induzido quimicamente , Aminoquinolinas/efeitos adversos , Antineoplásicos/efeitos adversos , Síndrome do Nevo Basocelular/tratamento farmacológico , Neoplasias de Cabeça e Pescoço/tratamento farmacológico , Líquen Plano/induzido quimicamente , Couro Cabeludo , Neoplasias Cutâneas/tratamento farmacológico , Toxidermias/etiologia , Feminino , Humanos , Imiquimode , Pessoa de Meia-Idade , Creme para a Pele/efeitos adversosAssuntos
Carcinoma Basocelular/diagnóstico , Neoplasias Cutâneas/diagnóstico , Carcinoma Basocelular/epidemiologia , Carcinoma Basocelular/patologia , Dermoscopia , Humanos , Masculino , Pessoa de Meia-Idade , Psoríase/epidemiologia , Neoplasias Cutâneas/epidemiologia , Neoplasias Cutâneas/patologiaRESUMO
The correct assessment of a solitary red nodule in clinical practice is of crucial importance, amelanotic melanoma being the most important differential diagnosis. Dermoscopy is nowadays a pivotal tool in the management of skin tumors, however it has some limitations in the evaluation of nonpigmented lesions, in which the diagnosis is merely based on the evaluation of the vascular pattern. Recently, reflectance confocal microscopy has been introduced as a new, noninvasive technique for the diagnosis of skin lesions. Confocal microscopy provides skin imaging in vivo at cellular level resolution, close to conventional histology. We present a series of clinical scenarios of red nodules, including melanoma metastasis, pyogenic granuloma, eccrine poroma, Spitz nevus and dermatofibroma. Reflectance confocal microscopy examination added important information to the clinical diagnosis and subsequent management in all cases except for dermatofibroma. We discuss the advantages and limitations of this technique in this particular field of application.
Assuntos
Melanoma Amelanótico/patologia , Microscopia Confocal/métodos , Neoplasias Cutâneas/patologia , Adolescente , Adulto , Brasil , Criança , Diagnóstico Diferencial , Feminino , Humanos , Masculino , Microscopia Confocal/normas , Dermatopatias/patologiaRESUMO
BACKGROUND: The clinical and dermoscopic diagnosis of cutaneous melanoma metastases may be challenging especially in patients with unknown primary melanoma. MAIN OBSERVATIONS: We observed repetitive dermoscopic patterns of peripheral stellate telangiectasias in cutaneous melanoma metastases from 3 patients, of whom 2 had an unknown primary melanoma. CONCLUSIONS: Stellate telangiectasias surrounding bluish to purple or red nodules with recent onset may represent a clue for cutaneous melanoma metastases.