RESUMO

Bioassay-guided purification of the organic crude extract of Alternaria solani resulted in the isolation of three metabolites responsible for causing necrosis on potato leaves. These phytotoxins were identified as 2-(2",3"-dimethyl-but-1-enyl)-zinniol (1), 8-zinniol methyl ether (2). and 8-zinniol methyl ether based on their spectroscopic data (IR, MS, 1H and 13CNMR). Metabolites 1 and 2 have been identified as new phytotoxins structurally related to zinniol (4). Additionally, 5-(3',3'-dimethylallyloxy)-7-methoxy-6-methyl-phthalide and 8-zinniol-2-(phenyl)-ethyl ether (3) were also isolated during the purification process.

Assuntos

Alternaria/química , Butanos/isolamento & purificação , Butanos/toxicidade , Éteres/isolamento & purificação , Éteres/toxicidade , Xilenos/isolamento & purificação , Xilenos/toxicidade , Butanos/química , Éteres/química , Necrose , Folhas de Planta , Solanum tuberosum , Análise Espectral , Xilenos/química