RESUMO
A violência contra a mulher, sendo um problema político-social, é algo que a sociedade e a comunidade científica não podem desconsiderar. Desse modo, a presença da Odontologia, no que tange às lesões do complexo bucomaxilofacial em mulheres, torna-se indispensável tanto na constatação quanto na reparação dos danos. Assim um estudo quantitativo e analítico, com desenho do tipo transversal, foi conduzido com o objetivo de caracterizar as lesões corporais e faciais em mulheres que se submeteram à perícia médico-legal no Instituto Médico Legal (IML), do município de Recife, PE, Brasil, no ocorridas nos meses de janeiro, abril e dezembro de 2005 e 2006 e janeiro e abril de 2007. Os dados foram compilados do laudo do legista, sendo as informações de interesse transcritas em ficha construída para tal fim. A maior participação nas solicitações de exame de corpo de delito coube às delegacias de Mulheres. Predominaram na amostra as lesões do tipo contundente e em mais de uma região corporal. Na face, a região mais acometida pela violência foi o terço médio. As lesões mais frequentes associadas aos tecidos foram as de tecidos moles. O agressor foi predominantemente o cônjuge, e as lesões classificadas como leve foram as mais comuns.
Violence against women is a political and social issue, is something that society and the scientific community can not ignore. Thus, the presence of Dentistry, in terms of complex maxillofacial injuries in women, it is essential both in finding how to repair the damage. Thus a quantitative and analytical, with a cross-sectional design was conducted in order to characterize and facial injuries in women who underwent medical and legal experts at the Institute of Forensic Medicine (IML) of the municipality of Recife, Brazil , occurred in the months of January, April and December 2005 and 2006, and January and April 2007. Data were compiled from the coroner's report and the information of interest statement transcribed m built for that purpose. The greater participation in the requests for a forensic examination to fit women's police stations. Predominated in the sample type injuries and bruising on more than one body region. On the face of the region most aff ected by violence was the middle third. The commonest injuries were associated with the tissues of the soft tissues. The gunman was predominantly the spouse and the lesions classified as mild were the most common.
RESUMO
BACKGROUND: Serotonin 1-A receptors are key regulators of serotonin activity and their dysregulation might be implicated in the emergence of both major depression (MD) and generalized anxiety disorder (GAD). Previous studies have yielded inconclusive results as to whether the 5-HT1A receptor gene (HTR1A) has a role in the aetiology of MD and no study up to date has analysed this polymorphism on either pure MD or MD comorbid with GAD. METHODS: In this study, 1059 patients taking part in the PREDICT-Gene study were ascertained for Diagnostic and Statistical Manual of Mental Disorders-IV MD and GAD diagnoses using the Composite International Diagnostic Interview and the Primary Care Evaluation of Mental Disorders questionnaire, respectively. They were also genotyped for the C(-1019)G functional polymorphism at the promoter region of HTR1A gene. RESULTS: Genetic variability at HTR1A was significantly associated with MD [odds ratio (OR) = 1.67; 95% confidence interval (CI) = 1.14-2.44; P = 0.008], although this effect disappeared after adjusting for GAD (OR = 1.43; 95% CI = 0.96-2.14; P = 0.080). Similarly, a crude association between C(-1019)G polymorphism and GAD was found (OR = 2.54; 95% CI = 1.28-4.86; P = 0.003), but these results became no longer significant after adjusting for MD (OR = 1.97; 95% CI = 0.99-3.91; P = 0.050). However, a main effect of HTR1A G(-1019) allele on comorbid MD-GAD was found (OR = 3.41; 95% CI = 1.44-8.05; P = 0.005) and it remained robust and statistically significant after adjusting by sex, age and family history of psychological problems (OR = 2.82; 95% CI = 1.18-6.77; P = 0.020). CONCLUSION: In our study, the HTR1A C(-1019)G polymorphism was found to be associated to the frequent clinical presentation of comorbid MD and GAD, suggesting a common genetic background for mixed depression and anxiety states. These findings should be considered as preliminary. Future replications in independent samples would be needed to confirm or discard such association.