RESUMO
The clearance pattern of a specific substance is very important to estimate its oral availability. Devices or models that simulate clearance in the mouth are important to study the effects and retention time of foods and drugs. This report describes an efficient device which was assembled with low-cost materials in our laboratory and that can be used to study the clearance of cariogenic substrates, mouthwashes, programmed-release drugs as well as adsorption of drugs to enamel. The device can have up to three chambers with varying minimum and maximum volumes that can be eluted simultaneously at different flows. The simulated swallowed volumes are adjustable and the ratio between the maximum and minimum volumes can be programmed. We also present the results of an evaluation study using the device to determine the clearance of fluoride from a fluoride-containing mouthwash, the clearance of a 1% glucose solution and the programmed release of fluoride from a methacrylate bioadhesive using artificial saliva as eluent.
Assuntos
Biofarmácia/instrumentação , Modelos Biológicos , Boca/metabolismo , Adsorção , Cariogênicos/farmacocinética , Cariostáticos/farmacocinética , Esmalte Dentário/metabolismo , Fluoretos/farmacocinética , Glucose/farmacocinética , Humanos , Taxa de Depuração Metabólica , Antissépticos Bucais/farmacocinética , Polimetil Metacrilato/química , Reprodutibilidade dos Testes , Saliva Artificial/metabolismoRESUMO
The objective of the present study is to know the importance of buccal health for adolescents of different social strata, identifying the importance of dental aesthetics, and the care that these students take in relation to their buccal health. The methodological process adopted in this investigation is of qualitative nature, using as technique of collection of data the semistructured interview. We know the importance of buccal health in several contexts of their lives, as in their personal appearance, sexuality, employment, and general health. This investigation allows us to know the motivations of adolescents to preserve their buccal health, and we believe to be so valid to develop health promotion through health education.
Assuntos
Serviços de Saúde do Adolescente , Assistência Odontológica , Adolescente , Brasil , Humanos , Classe SocialRESUMO
The objective of this work was to study the degree of the facial prognathism, considering the relationships between the SNA and SNB angles with the saddle angle (NSAr and NSBa). The sample consisted of eighty cephalometric roentgenograms, taken in lateral norm, of Brazilian white children, forty boys and forty girls, with both dental and skeletal, class I malocclusions, with ages between 9 years and 2 months old and 13 years and 7 months old. Data were statistically analysed and the sample was divided in three groups considering the mean value and the standard deviation of the NSAr angle. Sixteen subjects (seven boys and nine girls, 20 percent of the sample) presented an NSAr angle that was smaller than 119.5 degrees (x - 1s); twenty subjects (forteen boys and six girls, 25 percent of the sample), showed an NSAr angle more than 127.5 degrees (x + 1s) and forty-four subjects (nineteen boys and twenty-five girls, 55 percent of the sample) had an NSAr angle value between 119.5 and 127.5 degrees (x +/- 1s). The results led to the following conclusions: 1. There is a negative correlation, statistically significant between the saddle angle (NSAr and NSBa) with the SNA angle in subjects with class I malocclusions. An NSAr or NSBa angle higher than the mean value plus one standard deviation, it is associated with of the maxilla retrognathism and contrariwise. 2. There is a negative correlation, statistically significant between the sadle angle (NSAr and NSBa) with the SNB angle in subjects with malocclusions. An NSAr or NSBa angle higher than the mean value plus one standard deviation, it is associated with the mandible retrognathism and contrariwise. 3. The normal values of the SNA and SNB angles for an individual and the degree of the facial prognathism should be determined individually, since that the values of these angles might be affected for cranial base morphology.