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1.
Cir Cir ; 91(5): 685-689, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37844901

RESUMO

BACKGROUND: The expression of empathy improves the quality of health care, which is why its instruction is suggested during the years of academic training of medical students. However, expressing empathy can also cause anxiety and impair psychological well-being. OBJECTIVE: To identify profiles that describe the relationship between empathy, anxiety and psychological well-being in Mexican medical students. METHOD: Cross-sectional study in Mexican medical students completed the Multidimensional Empathy Scale, the Beck Anxiety Inventory, and the Psychological Well-Being Scale for Adults. RESULTS: Women presented greater empathy and anxiety and lower psychological well-being (p < 0.01). Anxiety in students of the last year of training was lower compared to students of the first and second year (p < 0.01). Four profiles were detected: 1) men, minimal anxiety, low empathy; 2) first-year students, moderate to severe anxiety, low psychological well-being, high empathy; 3) last year of training, mild anxiety, adequate psychological well-being, medium empathy; 4) women, second and third year of training, very high empathy. CONCLUSIONS: Medical students in their first year of training constitute a population at risk. Attention strategies are necessary for this student group.


ANTECEDENTES: La expresión de empatía mejora la calidad de la atención a la salud, y por ello se sugiere su instrucción durante los años de formación académica de estudiantes de medicina. No obstante, la expresión de empatía también puede ocasionar ansiedad y perjudicar el bienestar psicológico. OBJETIVO: Identificar perfiles que describan la relación entre empatía, ansiedad y bienestar psicológico en estudiantes mexicanos de medicina. MÉTODO: Estudio transversal en estudiantes mexicanos de medicina que completaron la Escala Multidimensional de Empatía, el Inventario de Ansiedad de Beck y la Escala de Bienestar Psicológico para Adultos. RESULTADOS: Las mujeres presentaron mayor empatía y ansiedad, y menor bienestar psicológico (p < 0.01). La ansiedad en estudiantes del último año de formación fue menor que en los estudiantes de primer y segundo año (p < 0.01). Se detectaron cuatro perfiles: 1) hombres, ansiedad mínima, empatía baja; 2) estudiantes de primer año de formación, ansiedad moderada a grave, bienestar psicológico bajo, empatía alta; 3) último año de formación, ansiedad leve, bienestar psicológico adecuado, empatía media; 4) mujeres, segundo y tercer años de formación, muy alta empatía. CONCLUSIONES: Los estudiantes de medicina del primer año de formación constituyen una población de riesgo. Son necesarias estrategias de atención para este grupo estudiantil.


Assuntos
Estudantes de Medicina , Masculino , Adulto , Humanos , Feminino , Estudantes de Medicina/psicologia , Bem-Estar Psicológico , Empatia , Estudos Transversais , Ansiedade/epidemiologia , Ansiedade/etiologia
2.
Cir Cir ; 90(4): 517-524, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35944455

RESUMO

OBJECTIVE: To identify the association between general empathy and medical empathy. Detect predictors of the level of medical empathy from general empathy. To determine the psychosocial profile that describes the relationship between general empathy, medical empathy, and demographic and academic characteristics in medical students. METHOD: Descriptive cross-sectional design. Medical students completed the Interpersonal Reactivity Index (IRI) and the Jefferson Scale of Physician Empathy-student version (JSPE-S). RESULTS: Relatively high levels of general and medical empathy were detected. The total score of the IRI and the JSPE-S and their dimensions correlated positively (r = 0.14-0.52), except for the dimension personal distress of the IRI. The score of the IRI dimension empathic concern was the best predictor of the JSPE-S score and its dimensions (b = 0.27-0.54). Four profiles were detected: 1) men, preference for technology-oriented specialty, less empathy; 2) pre-clinical period students, less empathy; 3) students of the clinical period, greater empathy; and 4) women, preference for patient-oriented specialty, greater empathy. CONCLUSIONS: General and medical empathy are associated. Differentiated empathic profiles will allow the design of instructional strategies in empathy according to the specific needs of each one.


OBJETIVO: Identificar la asociación entre empatía general y empatía médica. Detectar predictores del nivel de empatía médica a partir de la empatía general. Determinar el perfil psicosocial que describa la relación entre empatía general, empatía médica y características demográficas y académicas en estudiantes de medicina. MÉTODO: Estudio transversal descriptivo. Estudiantes de medicina completaron el Índice de Reactividad Interpersonal (IRI) y la Escala de Empatía Médica de Jefferson versión estudiantil (EEMJ-E). RESULTADOS: Se detectaron niveles relativamente altos de empatía general y médica. El puntaje total del IRI y la EEMJ-E y sus dimensiones se correlacionaron positivamente (r = 0.14-0.52), excepto para la dimensión malestar personal del IRI. El puntaje en la dimensión preocupación empática del IRI fue el mejor predictor del puntaje de la EEMJ-E y sus dimensiones (b = 0.27-0.54). Se detectaron cuatro perfiles: 1) hombres, preferencia por especialidad orientada a la tecnología, menor empatía; 2) estudiantes del periodo preclínico, menor empatía; 3) estudiantes del periodo clínico, mayor empatía; y 4) mujeres, preferencia por especialidad orientada al paciente, mayor empatía. CONCLUSIONES: La empatía general y la empatía médica se encuentran asociadas. Unos perfiles empáticos diferenciados permitirán el diseño de estrategias de instrucción en empatía acordes con las necesidades específicas de cada uno.


Assuntos
Medicina , Médicos , Estudantes de Medicina , Estudos Transversais , Empatia , Feminino , Humanos , Masculino , Médicos/psicologia , Estudantes de Medicina/psicologia
3.
Rev. CES psicol ; 14(3): 70-93, sep.-dic. 2021. tab, graf
Artigo em Espanhol | LILACS-Express | LILACS | ID: biblio-1376219

RESUMO

Resumen Introducción: El bienestar psicológico favorece el funcionamiento de la vida personal y social. Para su evaluación, es necesario contar con instrumentos válidos y confiables que permitan decidir y valorar las acciones necesarias para promoverlo. Objetivo: Evaluar las propiedades psicométricas de la Escala de Bienestar Psicológico para Adultos (BIEPS-A) en una muestra mexicana. Método: Se aplicó la escala BIEPS-A y la Escala de Autoestima de Rosenberg (EAR) a 188 estudiantes universitarios y 94 participantes de población general. Resultados: Un análisis paralelo detectó un factor único en la escala BIEPS-A, estructurado mediante análisis factorial exploratorio (componentes principales, rotación oblicua) que retuvo 9 reactivos y explicó el 54% de la varianza. La consistencia interna fue de aceptable (α de Cronbach = .78) a elevada (alfa ordinal = .90). El análisis de curva ROC identificó un punto de corte equivalente a la mediana (ABC = .72, p < .01) y otro al percentil 75 (ABC = .80, p < .01), y ser mujer, tener entre 18 y 25 años y bajo o leve nivel de autoestima como predictores de bajo nivel de bienestar psicológico. La escala BIEPS-A mostró validez concurrente (r = .57) y predictiva con la EAR (β = .63). Discusión y conclusiones: La escala BIEPS-A es un instrumento válido y confiable para evaluar el bienestar psicológico en población mexicana; sin embargo, las diferencias respecto a su estructura original indican la necesidad de una escala de bienestar psicológico diseñada específicamente para población mexicana.


Abstract Introduction: Psychological well-being favors the functioning of personal and social life. Valid and reliable instruments are necessary for its evaluation that allow deciding and assessing the actions necessary to promote it. Objective: To evaluate the psychometric properties of the Scale of Psychological Well-being for Adults (BIEPS-A) in a Mexican sample. Methods: The BIEPS-A scale and the Rosenberg Self-Esteem Scale (RSES) were administered to 188 university students and 94 participants from the general population. Results: A parallel analysis detected a single factor in the BIEPS-A scale, structured by exploratory factor analysis (main components, oblique rotation) that retained 9 items and explained 54% of the variance. Internal consistency ranged from acceptable (Cronbach's α = .78) to high (ordinal alpha = .90). ROC curve analysis identified a cut-off point equivalent to the median (AUC = .72, p <.01) and another to the 75th percentile (AUC = .80, p <.01). The latter identified as a woman, between 18 and 25 years old with a low or slight level of self-esteem as predictors of a low level of psychological well-being. The BIEPS-A scale showed concurrent (r = .57) and predictive (β = .63) validity with the EAR. Discussion and conclusions: The BIEPS-A scale is a valid and reliable instrument to assess psychological well-being in the Mexican population. However, the differences with respect to its original structure indicate the need for a psychological well-being scale designed specifically for the Mexican population.

4.
Salud ment ; Salud ment;43(3): 137-146, May.-Jun. 2020. tab, graf
Artigo em Inglês | LILACS-Express | LILACS | ID: biblio-1127310

RESUMO

Abstract Introduction Anxiety and depression in pregnant women are a public health problem. Their adequate detection requires valid and reliable instruments that are also useful for prevention and treatment. Objective To identify the psychometric properties of the Hospital Anxiety and Depression Scale (HADS) in a sample of Mexican pregnant women. Method The HADS was applied to 716 pregnant women between 13 and 46 years old (M = 26.55; SD = 6.56) attended in a public hospital in Mexico City. Results With a sample of 358 participants, a parallel analysis indicated a bifactorial structure for HADS, identified by exploratory factor analysis (Factor 1: anxiety, Factor 2: depression). The factors explained 53% of the variance and correlated positively (r = .36). The global internal consistency (Cronbach's α = .81; ordinal α = .93) and by factor (anxiety: Cronbach's α = .79; ordinal α = .88; depression: Cronbach's α = .79; ordinal α = .87) was acceptable. With data from the remaining 358 participants, a confirmatory factor analysis showed an acceptable fit for the structure detected (χ2/gl = 2.72; RMSEA = .06 [IC .05, .08]; GFI = .93; AGFI = .90; TLI = .90; CFI = .92). Discussion and conclusions The Hospital Anxiety and Depression Scale has adequate psychometric properties to be used in pregnant Mexican women. Its use in routine pregnancy controls would be useful to prevent, detect, and timely treat these conditions.


Resumen Introducción La ansiedad y la depresión en gestantes representan un problema de salud pública. Su adecuada detección requiere de instrumentos válidos y confiables que también sirvan para su prevención y tratamiento. Objetivo Identificar las propiedades psicométricas de la Escala Hospitalaria de Ansiedad y Depresión (HADS) en una muestra de mujeres embarazadas mexicanas. Método Se aplicó la HADS a 716 gestantes de entre 13 y 46 años (M = 26.55; DE = 6.56), atendidas en un hospital público en la Ciudad de México. Resultados Con una muestra de 358 participantes, un análisis paralelo indicó una estructura bifactorial para la HADS, identificada mediante análisis factorial exploratorio (Factor 1: ansiedad, Factor 2: depresión). Los factores explicaron el 53% de la varianza y correlacionaron positivamente (r = .36). La consistencia interna global (α de Cronbach = .81, α ordinal = .93) y por factor (ansiedad: αde Cronbach = .79, α ordinal = .88; depresión: α de Cronbach = .79, α ordinal = .87) fue aceptable. Con los datos de las 358 participantes restantes, un análisis factorial confirmatorio mostró un ajuste aceptable para la estructura detectada (χ2/gl = 2.72; RMSEA = .06 [IC .05, .08]; GFI = .93; AGFI = .90; TLI = .90; CFI = .92). Discusión y conclusión La Escala Hospitalaria de Ansiedad y Depresión posee adecuadas propiedades psicométricas para su empleo en mujeres embarazadas mexicanas. Su uso en controles rutinarios del embarazo sería útil para prevenir, detectar y atender oportunamente estos padecimientos.

5.
Gac Med Mex ; 156(1): 40-46, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32026880

RESUMO

INTRODUCTION: Medical students report higher levels of anxiety than students from other majors. Knowledge about their psychological well-being is scarce. OBJECTIVE: To identify sociodemographic and academic factors that predict the level of anxiety and psychological well-being in Mexican medical students. METHOD: Cross-sectional study of Mexican medical students of first (n = 59), third (n = 43) and fifth semester (n = 59), who answered a sociodemographic questionnaire, Beck Anxiety Inventory, the Psychological Well-being Scale for adults and the Family Adaptability and Cohesion Evaluation Scale. RESULTS: Females showed higher levels of anxiety (p < 0.01). Anxiety in males was similar in the different semesters (p > 0.05); women of third and fifth semesters were more anxious than those at first semester (p < 0.01). Anxiety and psychological well-being were negatively correlated (p < 0.001). The "Less anxiety, higher level of well-being" and "More anxiety, lower level of well-being" subgroups were characterized, and a logistic regression identified that being a woman (OR = 4.70) and not practicing any religion (OR = 2.49) are predictive factors of higher levels of anxiety. CONCLUSIONS: Female medical students constitute a population at risk for higher levels of anxiety and less psychological well-being, which compromises their learning, quality of life and future professional practice.


INTRODUCCIÓN: Estudiantes de medicina reportan mayor ansiedad que estudiantes de otras carreras. El conocimiento sobre su bienestar psicológico es escaso. OBJETIVO: Identificar factores sociodemográficos y académicos predictores del nivel de ansiedad y bienestar psicológico en estudiantes mexicanos de medicina. MÉTODO: Estudio transversal de estudiantes mexicanos de medicina de primer (n = 59), tercer (n = 43) y quinto semestre (n = 59), que contestaron un cuestionario sociodemográfico, la Escala de Ansiedad de Beck, la Escala de Bienestar Psicológico para Adultos y la Escala de Evaluación de la Cohesión y la Adaptabilidad Familiar. RESULTADOS: Las mujeres presentaron mayor ansiedad (p < 0.01). La ansiedad en hombres fue similar en los distintos semestres (p > 0.05); las mujeres de tercer y quinto semestre fueron más ansiosas que las del primero (p < 0.01). Ansiedad y bienestar psicológico correlacionaron negativamente (p < 0.001). Se identificaron los subgrupos "Menor ansiedad, mayor bienestar" y "Mayor ansiedad, menor bienestar", y una regresión logística identificó que ser mujer (OR = 4.70) y no profesar alguna religión (OR = 2.49) son factores predictores de mayor ansiedad. CONCLUSIONES: Las estudiantes de medicina constituyen una población de riesgo para mayor ansiedad y menor bienestar psicológico, lo que compromete su aprendizaje, calidad de vida y futuro ejercicio profesional.


Assuntos
Ansiedade/epidemiologia , Saúde Mental/estatística & dados numéricos , Estudantes de Medicina/psicologia , Desempenho Acadêmico , Estudos Transversais , Feminino , Humanos , Modelos Logísticos , Masculino , México/epidemiologia , Testes Psicológicos , Religião e Psicologia , Fatores Sexuais , Estudantes de Medicina/estatística & dados numéricos , Adulto Jovem
6.
Gac. méd. Méx ; Gac. méd. Méx;156(1): 40-46, ene.-feb. 2020. tab
Artigo em Espanhol | LILACS | ID: biblio-1249868

RESUMO

Resumen Introducción: Estudiantes de medicina reportan mayor ansiedad que estudiantes de otras carreras. El conocimiento sobre su bienestar psicológico es escaso. Objetivo: Identificar factores sociodemográficos y académicos predictores del nivel de ansiedad y bienestar psicológico en estudiantes mexicanos de medicina. Método: Estudio transversal de estudiantes mexicanos de medicina de primer (n = 59), tercer (n = 43) y quinto semestre (n = 59), que contestaron un cuestionario sociodemográfico, la Escala de Ansiedad de Beck, la Escala de Bienestar Psicológico para Adultos y la Escala de Evaluación de la Cohesión y la Adaptabilidad Familiar. Resultados: Las mujeres presentaron mayor ansiedad (p < 0.01). La ansiedad en hombres fue similar en los distintos semestres (p > 0.05); las mujeres de tercer y quinto semestre fueron más ansiosas que las del primero (p < 0.01). Ansiedad y bienestar psicológico correlacionaron negativamente (p < 0.001). Se identificaron los subgrupos “Menor ansiedad, mayor bienestar” y “Mayor ansiedad, menor bienestar”, y una regresión logística identificó que ser mujer (OR = 4.70) y no profesar alguna religión (OR = 2.49) son factores predictores de mayor ansiedad. Conclusiones: Las estudiantes de medicina constituyen una población de riesgo para mayor ansiedad y menor bienestar psicológico, lo que compromete su aprendizaje, calidad de vida y futuro ejercicio profesional.


Abstract Introduction: Medical students report higher levels of anxiety than students from other majors. Knowledge about their psychological well-being is scarce. Objective: To identify sociodemographic and academic factors that predict the level of anxiety and psychological well-being in Mexican medical students. Method: Cross-sectional study of Mexican medical students of first (n = 59), third (n = 43) and fifth semester (n = 59), who answered a sociodemographic questionnaire, Beck Anxiety Inventory, the Psychological Well-being Scale for adults and the Family Adaptability and Cohesion Evaluation Scale. Results: Females showed higher levels of anxiety (p < 0.01). Anxiety in males was similar in the different semesters (p > 0.05); women of third and fifth semesters were more anxious than those at first semester (p < 0.01). Anxiety and psychological well-being were negatively correlated (p < 0.001). The “Less anxiety, higher level of well-being” and “More anxiety, lower level of well-being” subgroups were characterized, and a logistic regression identified that being a woman (OR = 4.70) and not practicing any religion (OR = 2.49) are predictive factors of higher levels of anxiety. Conclusions: Female medical students constitute a population at risk for higher levels of anxiety and less psychological well-being, which compromises their learning, quality of life and future professional practice.


Assuntos
Humanos , Masculino , Feminino , Adulto Jovem , Ansiedade/epidemiologia , Estudantes de Medicina/psicologia , Saúde Mental/estatística & dados numéricos , Testes Psicológicos , Religião e Psicologia , Estudantes de Medicina/estatística & dados numéricos , Modelos Logísticos , Fatores Sexuais , Estudos Transversais , Desempenho Acadêmico , México/epidemiologia
7.
Medisur ; 18(1): 41-49, ene.-feb. 2020. tab
Artigo em Espanhol | LILACS-Express | LILACS | ID: biblio-1125175

RESUMO

RESUMEN Fundamento: la expresión de empatía en la relación médico-paciente presenta múltiples beneficios en la atención a la salud. La evidencia indica menor empatía en fases avanzadas del desarrollo curricular en medicina. Existe escasa información al respecto en población mexicana. Objetivo: identificar el nivel de empatía general y sus factores asociados en tres momentos distintos del desarrollo curricular en estudiantes mexicanos de medicina. Métodos: estudio transversal, realizado en la Escuela de Medicina de una universidad privada en la Ciudad de México, sobre 161 estudiantes de medicina inscritos en primer, tercer y quinto semestre de la carrera de medicina que completaron la escala multidimensional de empatía, versión reducida. Se realizaron análisis por semestre y sexo; se identificaron subgrupos con diferente nivel de empatía y se realizó un análisis con estimadores de riesgo. Resultados: las mujeres fueron más empáticas que los hombres (p = 0,0001) excepto en la detección de emociones ajenas que no mostró diferencias entre sexos (p = 0,99). Las mujeres no mostraron diferencias entre semestres (p > 0,05), los hombres de primer semestre fueron más empáticos que los de tercero y quinto (p = 0,005) particularmente para detectar emociones ajenas (p = 0,002). Ser hombre aumentó la probabilidad de mostrar menor nivel de empatía (OR = 2,36, p = 0,02). Conclusiones: el menor nivel de empatía en estudiantes hombres de semestres avanzados de medicina puede comprometer los beneficios hasta ahora reportados de la expresión de esta habilidad en la relación médico-paciente y en consecuencia disminuir la calidad de la atención. Es necesaria una estrategia de instrucción en empatía para este grupo estudiantil.


ABSTRACT Foundation: the expression of empathy in the doctor-patient relationship has multiple benefits in health care. The evidence indicates lower empathy in advanced stages of curriculum development in medicine. There is little information about it in the Mexican population. Objective: to identify the level of general empathy and its associated factors in three different moments of the curricular development in Mexican medical students. Methods: a cross-sectional study, conducted at the Higher School of Medicine of a private university in Mexico City, on 161 medical students enrolled in the first, third and fifth semesters of the medical degree that completed the multidimensional empathy scale, reduced version. Analyzes were performed by semester and sex; Subgroups with different levels of empathy were identified and an analysis was carried out with risk estimators. Results: women were more empathetic than men (p = 0.0001) except in the detection of other people's emotions that showed no differences between sexes (p = 0.99). Women did not show differences between semesters (p> 0.05), the first semester men were more empathetic than the third and fifth (p = 0.005), particularly to detect other people's emotions (p = 0.002). Being a man increased the probability of showing a lower level of empathy (OR = 2.36, p = 0.02). Conclusions: the lower empathy level in male students of advanced medicine semesters can compromise the benefits so far reported of the ability expression in the doctor-patient relationship and consequently decreases the quality of care. An empathy instructional strategy is necessary for this student group.

8.
Gac Med Mex ; 155(3): 307-318, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-31219471

RESUMO

The interest on cannabinoids became evident between the 1940 and 1950 decades. Although the active substance of the plant was not known, a series of compounds with cannabinomimetic activity were synthesized, which were investigated in animals and clinically. The most widely tested was Δ6a, 10a-THC hexyl. Δ6a, 10a-THC dimethylheptyl (DMHP) antiepileptic effects were studied in several children, with positive results being obtained in some cases. DMHP differs from sinhexyl in that its side chain is DMHP instead of n-hexyl. The first cannabinoid isolated from Cannabis sativa was cannabinol, although its structure was correctly characterized several years later. Cannabidiol was isolated some years later and was subsequently characterized by Mechoulam and Shvo. In 2013, the National Academy of Medicine and the Faculty of Medicine of the National Autonomous University of Mexico, through the Seminar of Studies on Entirety, decided to carry out a systematic review on a subject that is both complex and controversial: the relationship between marijuana and health. In recent years, studies have been conducted with cannabis in several diseases: controlled clinical trials on spasticity in multiple sclerosis and spinal cord injury, chronic, essentially neuropathic, pain, movement disorders (Gilles de Latourette, dystonia, levodopa dyskinesia), asthma and glaucoma, as well as non-controlled clinical trials on Alzheimer's disease, neuroprotection, intractable hiccups, epilepsy, alcohol and opioid dependence and inflammatory processes.


El interés por los cannabinoides se hizo evidente entre las décadas de 1940 y 1950. Aunque no se conocía el principio activo de la planta, se sintetizaron compuestos con actividad cannabinomimética, los cuales fueron investigados en animales y en la clínica. El más probado fue el ∆6a,10a-THC hexilo. Las acciones antiepilépticas del ∆6a,10a-THC dimetilheptil fueron estudiadas en varios niños; en algunos casos se obtuvieron resultados positivos. El ∆6a,10a-THC dimetilheptil se diferencia del sinhexil en que su cadena lateral es dimetilheptilo en vez de n-hexilo. El primer cannabinoide aislado de Cannabis sativa fue el cannabinol, si bien su estructura fue correctamente caracterizada varios años después. El cannabidiol fue aislado algunos años más tarde y caracterizado posteriormente por Mechoulam y Shvo. Durante 2013, la Academia Nacional de Medicina y la Facultad de Medicina de la Universidad Nacional Autónoma de México, a través del Seminario de Estudios sobre la Globalidad, decidieron realizar una revisión sistemática sobre un tema tan complejo como controvertido: la relación entre la marihuana y la salud. En los últimos años se han realizado estudios con cannabis en varias enfermedades: ensayos clínicos controlados sobre espasticidad en esclerosis múltiple y sobre lesiones medulares, dolor crónico fundamentalmente neuropático y trastornos del movimiento (Gilles de Latourette, distonía, discinesia por levodopa), asma y glaucoma, así como ensayos clínicos no controlados sobre Alzheimer, neuroprotección, hipo intratable, epilepsia, dependencia al alcohol y opioides y procesos inflamatorios.


Assuntos
Canabidiol/isolamento & purificação , Canabinoides/uso terapêutico , Cannabis/química , Animais , Canabidiol/química , Canabinoides/química , Canabinoides/isolamento & purificação , Canabinol/química , Canabinol/isolamento & purificação , Humanos
9.
Gac. méd. Méx ; Gac. méd. Méx;155(3): 307-318, may.-jun. 2019. tab
Artigo em Inglês | LILACS | ID: biblio-1286504

RESUMO

The interest on cannabinoids became evident between the 1940 and 1950 decades. Although the active substance of the plant was not known, a series of compounds with cannabinomimetic activity were synthesized, which were investigated in animals and clinically. The most widely tested was Δ6α, 10α-THC hexyl. Δ6α, 10α-THC dimethylheptyl (DMHP) antiepileptic effects were studied in several children, with positive results being obtained in some cases. DMHP differs from sinhexyl in that its side chain is DMHP instead of n-hexyl. The first cannabinoid isolated from Cannabis sativa was cannabinol, although its structure was correctly characterized several years later. Cannabidiol was isolated some years later and was subsequently characterized by Mechoulam and Shvo. In 2013, the National Academy of Medicine and the Faculty of Medicine of the National Autonomous University of Mexico, through the Seminar of Studies on Entirety, decided to carry out a systematic review on a subject that is both complex and controversial: the relationship between marijuana and health. In recent years, studies have been conducted with cannabis in several diseases: controlled clinical trials on spasticity in multiple sclerosis and spinal cord injury, chronic, essentially neuropathic, pain, movement disorders (Gilles de Latourette, dystonia, levodopa dyskinesia), asthma and glaucoma, as well as non-controlled clinical trials on Alzheimer’s disease, neuroprotection, intractable hiccups, epilepsy, alcohol and opioid dependence and inflammatory processes.


Assuntos
Humanos , Animais , Canabidiol/isolamento & purificação , Canabinoides/uso terapêutico , Cannabis/química , Canabidiol/química , Canabinoides/isolamento & purificação , Canabinoides/química , Canabinol/isolamento & purificação , Canabinol/química
10.
Gac Med Mex ; 154(6): 729-731, 2018.
Artigo em Espanhol | MEDLINE | ID: mdl-30532092

RESUMO

In recent years, the use of stem cells for therapeutic purposes has received attention from research groups. In Mexico, the Mexican Official Standard 260-SSAI-2015 regarding the use of stem and progenitor cells for therapeutic and research purposes is in the process of authorization. Even when this has not been approved, an increasing number of establishments are offering medical services involving the use of stem cells for therapeutic purposes without official regulatory authorization. The Mexican Academy of Medicine of Mexico makes its position public in favor of regulating the use of stem cells and embryos for therapeutic and research purposes.


En años recientes, el uso de células troncales con fines terapéuticos ha recibido atención por grupos de investigación. En México está en proceso de autorización la Norma oficial mexicana 260-SSAI-2015, para la disposición de células troncales y progenitoras con fines terapéuticos y de investigación. Aun cuando esta no ha sido aprobada, cada vez más establecimientos ofrecen servicios médicos con la finalidad de usar células madres con fines terapéuticos sin contar con las autorizaciones sanitarias oficiales. La Academia Nacional de Medicina de México da a conocer su posición acerca de la regulación sobre el uso de células troncales y embriones para fines terapéuticos o de investigación.


Assuntos
Pesquisa com Células-Tronco , Transplante de Células-Tronco/métodos , Células-Tronco/citologia , Academias e Institutos , Pesquisa Biomédica/métodos , Humanos , México
11.
Gac Med Mex ; 154(6): 740-741, 2018.
Artigo em Espanhol | MEDLINE | ID: mdl-30532103

RESUMO

In Mexico there is a proliferation of "centers for aesthetic medicine" that offer different treatments with laser beam, mesotherapy and hyaluronic acid and botulinum toxin injections. In numerous centers of this type, offered and performed by medical personnel that are neither trained or certified to ensure the quality of services. The National Academy of Medicine of Mexico and the National Normative Council for Medical Specialties (CONACEM) communicate their posture on this matter.


En México existe una proliferación de "centros de medicina estética" que ofrecen tratamientos diversos con rayos láser, mesoterapia, ácido hialurónico e inyecciones con toxina botulínica por personal médico que no está capacitado ni certificado para asegurar la calidad de los servicios. La Academia Nacional de Medicina y el Comité Normativo Nacional de Consejos de Especialidades Médicas (CONACEM) comunican su postura al respecto.


Assuntos
Técnicas Cosméticas , Estética , Academias e Institutos , Toxinas Botulínicas/administração & dosagem , Técnicas Cosméticas/normas , Humanos , Ácido Hialurônico/administração & dosagem , Terapia a Laser/métodos , Mesoterapia/métodos , México
12.
Gac Med Mex ; 154(6): 732-736, 2018.
Artigo em Espanhol | MEDLINE | ID: mdl-30532104

RESUMO

There are decisions at the end of life that currently are relevant as humanistic values. Respect for human life and dignity are part of human rights. The National Academy of Medicine of Mexico declares its posture about end-of-life decisions that include treatment refusal, limitation of the therapeutic effort, advance directives and palliative sedation, among others, with the purpose to favor a peaceful death.


Hay decisiones relacionadas con el final de la vida que actualmente son relevantes como valores humanísticos. El respeto y la dignidad de la vida humana están incluidos en los derechos humanos. La Academia Nacional de Medicina de México declara su postura acerca de las decisiones sobre el final de la vida que incluyen rechazo a un tratamiento, limitación del esfuerzo terapéutico, voluntad anticipada y sedación paliativa, entre otros, con la finalidad de propiciar una muerte en paz.


Assuntos
Tomada de Decisões , Direitos Humanos , Pessoalidade , Assistência Terminal/métodos , Academias e Institutos , Diretivas Antecipadas , Humanos , México , Cuidados Paliativos/métodos , Recusa do Paciente ao Tratamento
13.
Gac Med Mex ; 154(6): 737-739, 2018.
Artigo em Espanhol | MEDLINE | ID: mdl-30532119

RESUMO

As a consequence of the Presidential Decree that reforms and additions the General Statute of Health with regard to medicinal and scientific use of tetrahydrocannabinol, its isomers and stereochemical variants, the National Academy of Medicine of Mexico declares its position in favor of regulating investigation and national production thereof.


Como consecuencia del decreto presidencial que reforma y adiciona la Ley General de Salud respecto al uso medicinal y científico del tetrahidrocannabinol, sus isómeros y variantes estereoquímicas, la Academia Nacional de Medicina de México declara su posición para normar la investigación y producción nacional de los mismos.


Assuntos
Cannabis/química , Dronabinol/administração & dosagem , Política de Saúde , Maconha Medicinal/administração & dosagem , Academias e Institutos , Dronabinol/química , Humanos , Isomerismo , México
14.
Cancer Causes Control ; 24(2): 217-31, 2013 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-23224270

RESUMO

BACKGROUND: Latin America has among the highest gastric cancer incidence rates in the world, for reasons that are still unknown. In order to identify region-specific risk factors for gastric cancer, we conducted a meta-analysis summarizing published literature. METHODS: Searches of PubMed and regional databases for relevant studies published up to December 2011 yielded a total of 29 independent case-control studies. We calculated summary odds ratios (OR) for risk factors reported in at least five studies, including socioeconomic status (education), lifestyle habits (smoking and alcohol use), dietary factors (consumption of fruits, total vegetables, green vegetables, chili pepper, total meat, processed meat, red meat, fish, and salt), and host genetic variants (IL1B-511T, IL1B-31C, IL1RN*2, TNFA-308A, TP53 codon 72 Arg, and GSTM1 null). Study-specific ORs were extracted and summarized using random-effects models. RESULTS: Chili pepper was the only region-specific factor reported in at least five studies. Consistent with multifactorial pathogenesis, smoking, alcohol use, high consumption of red meat or processed meat, excessive salt intake, and carriage of IL1RN*2 were each associated with a moderate increase in gastric cancer risk. Conversely, higher levels of education, fruit consumption, and total vegetable consumption were each associated with a moderately decreased risk. The other exposures were not significantly associated. No prospective study data were identified. CONCLUSION: Risk factor associations for gastric cancer in Latin America are based on case-control comparisons that have uncertain reliability, particularly with regard to diet; the specific factors identified and their magnitudes of association are largely similar to those globally recognized. Future studies should emphasize prospective data collection and focus on region-specific exposures that may explain high gastric cancer risk.


Assuntos
Neoplasias Gástricas/epidemiologia , Dieta , Comportamento Alimentar , Humanos , América Latina/epidemiologia , Estilo de Vida , Razão de Chances , Fatores de Risco , Neoplasias Gástricas/etiologia
15.
J Immigr Minor Health ; 13(6): 1142-9, 2011 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-20811952

RESUMO

In the US, Mexican immigrant women often have better health outcomes than non-Hispanic white women despite a greater health risk profile. This cross-sectional pilot study compared women living in Chavinda, Michoacán (n = 102) to women who had migrated from Mexico to Madera, California (n = 93). The interview gathered information on acculturation and risk behaviors including smoking, alcohol use and number of sexual partners. The results suggest that more acculturated women living in the US are more likely to consume alcohol. US residence and higher acculturation level was marginally associated with having more than one sexual partner. There were no differences between odds of smoking among Chavinda and Madera women. While results with acculturation are not consistently significant due to small sample sizes, the results are suggestive that acculturation among immigrant Hispanic women in the US may be associated with adverse health behaviors, and selective migration seems less likely to account for these differences.


Assuntos
Emigração e Imigração , Comportamentos Relacionados com a Saúde/etnologia , Aculturação , Adolescente , Adulto , California , Estudos Transversais , Feminino , Humanos , Entrevistas como Assunto , México , Pessoa de Meia-Idade , Projetos Piloto , Assunção de Riscos , Inquéritos e Questionários , Adulto Jovem
16.
Gac. méd. Méx ; Gac. méd. Méx;143(5): 377-381, sept.-oct. 2007. tab, ilus
Artigo em Espanhol | LILACS | ID: lil-568648

RESUMO

Objetivo: Describir la relación de los niveles de plomo en sangre y reprobación escolar. Material y métodos: Estudio transversal en 792 escolares de 7 a 14 años de edad asistentes a la consulta externa de cinco hospitales pediátricos de la ciudad de México en 1996. Se midió el nivel de plomo en sangre, se exploró la exposición al metal, así como el desempeño académico. Resultados: Se reportó una media de plomo en sangre de 8.6 μg/dL y una media geométrica de 7.7 μg/dL. La principal fuente de exposición fue el uso de loza de barro vidriado (diferencia de uso = –1.182, p = 0.000). En los escolares que reprobaron algún año, la media geométrica de plomo en sangre fue de 8.1 μg/dL, en comparación con los niños que no reprobaron (media geométrica = 7.6 μg/dL, p = 0.240). El riesgo de reprobar entre el primer y el tercer año de primaria con plomo en sangre mayor a 10 μg/dL fue de 1.73 (p=0.012, IC 95% 1.13-2.66), y del primero al cuarto año de primaria fue de 1.62 (p=0.021, IC 95% 1.07-2.46). Conclusiones: Es probable que el plomo sanguíneo, entre otros condicionantes, contribuya a la reprobación repetida en los escolares de este estudio.


OBJECTIVE: To describe the relationship between blood lead levels (BLL) and poor school performance. MATERIAL AND METHODS: A cross-sectional study was carried out in 1996 among 792 schoolchildren aged 7-14 years, who attended the outpatient units of five pediatric hospitals of Mexico City. BLL was measured together with lead exposure and academic performance. RESULTS: Reported BLL and geometric means (GM) were 8.6 microg/dL and 7.7 microg/dL, respectively. The main source of exposure was the use of glazed pottery (difference of use =-1.182; p = 0.000). Among schoolchildren who failed any school year, GM of the BLL was 8.1 microg/dL, compared with children who did not fail (GM = 7.6 microg/dL; p = 0.240). The risk of failing a school year between the 1st and 3rd grade with a BLL greater than 10 microg/dL was 1.73 (p = 0.012, IC 95% 1.13-2.66) and from 1st to 4th grade was 1.62 (p = 0.021, IC 95% 1.07-2.46). CONCLUSIONS: Blood lead levels, among other conditions, may contribute to the failure in school performance observed in the children participating in this study.


Assuntos
Humanos , Masculino , Feminino , Criança , Adolescente , Logro , Chumbo/sangue , Estudos Transversais , México , População Urbana
17.
Gac Med Mex ; 143(5): 377-81, 2007.
Artigo em Espanhol | MEDLINE | ID: mdl-18246931

RESUMO

OBJECTIVE: To describe the relationship between blood lead levels (BLL) and poor school performance. MATERIAL AND METHODS: A cross-sectional study was carried out in 1996 among 792 schoolchildren aged 7-14 years, who attended the outpatient units of five pediatric hospitals of Mexico City. BLL was measured together with lead exposure and academic performance. RESULTS: Reported BLL and geometric means (GM) were 8.6 microg/dL and 7.7 microg/dL, respectively. The main source of exposure was the use of glazed pottery (difference of use =-1.182; p = 0.000). Among schoolchildren who failed any school year, GM of the BLL was 8.1 microg/dL, compared with children who did not fail (GM = 7.6 microg/dL; p = 0.240). The risk of failing a school year between the 1st and 3rd grade with a BLL greater than 10 microg/dL was 1.73 (p = 0.012, IC 95% 1.13-2.66) and from 1st to 4th grade was 1.62 (p = 0.021, IC 95% 1.07-2.46). CONCLUSIONS: Blood lead levels, among other conditions, may contribute to the failure in school performance observed in the children participating in this study.


Assuntos
Logro , Chumbo/sangue , Adolescente , Criança , Estudos Transversais , Feminino , Humanos , Masculino , México , População Urbana
18.
Salud Publica Mex ; 48 Suppl 1: S5-16, 2006.
Artigo em Espanhol | MEDLINE | ID: mdl-17684690

RESUMO

OBJECTIVE: This study presents findings from the Global Youth Tobacco Survey (GYTS) regarding current cigarette smoking and other tobacco epidemic indicators. MATERIAL AND METHODS: The GYTS used a two-stage cluster sample survey to generate representative samples of students aged 12 to 15 years old enrolled in public, private and technical schools. The survey was undertaken at 492 schools in 21 cities. The GYTS surveyed 42,024 students between the years 2003 and 2005. A logistic regression model was applied and crude and adjusted odds ratios were estimated. RESULTS: The overall current smoking rate during the 30 days preceding the survey was 19.96% (95% CI 18.1-21.8). Among those who never smoked, 25% were likely to begin smoking in the following year. Sixty percent of current smokers who bought their cigarettes in stores were not refused purchase because of their age. Exposure to advertising in outside areas was 86 and 54% of students reported to have been exposed to smoke in public places. CONCLUSION: Comprehensive tobacco control programs should prevent access by minors to cigarettes, make it more difficult to smoke, and prohibit all forms of tobacco advertising. In addition, options should be provided for those who wish to quit smoking and adolescents and their families should be educated with respect to the dangers of smoking.


Assuntos
Publicidade/legislação & jurisprudência , Prevenção do Hábito de Fumar , Fumar/epidemiologia , Indústria do Tabaco/legislação & jurisprudência , Adolescente , Fatores Etários , Criança , Coleta de Dados , Feminino , Educação em Saúde , Humanos , Modelos Logísticos , Masculino , México/epidemiologia , Análise Multivariada , Razão de Chances , Vigilância da População , Prevalência , Fatores Sexuais , Fumar/legislação & jurisprudência , Abandono do Hábito de Fumar , Fatores Socioeconômicos
19.
Salud Publica Mex ; 48 Suppl 1: S83-90, 2006.
Artigo em Espanhol | MEDLINE | ID: mdl-17684693

RESUMO

OBJECTIVE: To characterize tobacco use according to level of poverty in a random, nationally representative sample of adolescents (10 to 21 years old), living in urban areas with less than 50,000 inhabitants. The study was done in 2001 as part of the baseline assessment of the evaluation of the governmental program, Oportunidades. MATERIAL AND METHODS: A questionnaire was applied to 29,548 adolescents living in 30 000 selected households and it included specific questions on individual tobacco use among other questions. RESULTS: The prevalence of smokers was 3.5% (95% CI: 3.3%-3.7%) and experimenters 9.9% (95% CI: 9.6%-10.2%). A logistic regression model for clustered data was constructed in order to evaluate the associated factors that distinguish a smoker from an experimenter. After adjusting for level of poverty of the household and use of alcohol and drugs, a significant association (OR = 1.5, p <0.01) was found with having a paid job and a differential association was found between gender and age group. CONCLUSIONS: The results of this study suggest that the additional availability of money that an adolescent has, could increase the prevalence of tobacco smoking and that the program Oportunidades should include prevention campaigns directed specifically at this population group.


Assuntos
Pobreza , Fumar/epidemiologia , Adolescente , Adulto , Fatores Etários , Criança , Feminino , Humanos , Modelos Logísticos , Masculino , México/epidemiologia , Prevalência , Fatores Sexuais , Inquéritos e Questionários , População Urbana
20.
Salud pública Méx ; 48(supl.1): s5-s16, 2006.
Artigo em Espanhol | LILACS | ID: lil-431303

RESUMO

OBJETIVO: Analizar la información de la Encuesta sobre Tabaquismo en Jóvenes (ETJ) sobre consumo de cigarrillo y otros indicadores que resulten útiles para una medición inicial de las condiciones en que el país ratificó el Convenio Marco para el Control del Tabaco (CMCT). MATERIAL Y MÉTODOS: La ETJ usa un diseño de muestreo por conglomerado en dos etapas que genera muestras representativas de estudiantes de 12 a 15 años de las escuelas secundarias públicas, privadas y técnicas. Incluye 42 024 estudiantes de 492 escuelas en el periodo 2003-2005. Se aplicó un modelo de regresión logística y se obtuvieron razones de momios crudas y ajustadas. RESULTADOS: La prevalencia de fumadores en el mes anterior a la encuesta fue de 19.96 por ciento (IC95 por ciento 18.1-21.8). El índice de susceptibilidad de iniciarse en el consumo de cigarrillos fue de 25 por ciento. A 60 por ciento de los fumadores que compraron cigarrillos no les negaron la venta por ser menores de edad. El 54 por ciento de los estudiantes declara que está expuesto al humo de tabaco en lugares públicos y 86 por ciento ha visto anuncios de cigarrillos en exteriores en el mes previo a la encuesta. CONCLUSION: Una intervención integral debe orientarse a impedir el acceso de los menores a los cigarrillos; dificultar el acto de fumar y prohibir toda forma de publicidad del tabaco. Asimismo, se deben ofrecer opciones a quienes deseen dejar de fumar y educar a los adolescentes y sus familias sobre los daños a la salud de los fumadores y no fumadores.


Assuntos
Adolescente , Criança , Feminino , Humanos , Masculino , Publicidade/legislação & jurisprudência , Fumar/epidemiologia , Fumar/prevenção & controle , Indústria do Tabaco/legislação & jurisprudência , Fatores Etários , Coleta de Dados , Educação em Saúde , Modelos Logísticos , México/epidemiologia , Análise Multivariada , Razão de Chances , Vigilância da População , Prevalência , Fatores Sexuais , Abandono do Hábito de Fumar , Fumar/legislação & jurisprudência , Fatores Socioeconômicos
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