RESUMO
BACKGROUND: In woman aged over 60 years, body changes occur and might cause insulin resistance and metabolic syndrome. OBJECTIVE: To determine the relationship between the components of metabolic syndrome, insulin resistance and body mass index in women over 60 years, attended at the Geriatric Services in the Dr. Ignacio Morones Prieto Hospital in San Luis Potosi, Mexico. MATERIAL AND METHOD: We performed an observational, descriptive and transversal study with non-probability sampling, selecting 61 women aged 60 years attended from 2006 to 2008, who have measured the body mass index (BMI), insulin resistance and homeostasis model (HOMA2), and identifying the components of metabolic syndrome according to the criteria of the World Health Organization. We used descriptive and inferential statistics with r Pearson and Chi Square. RESULTS: The mean age was 68 years. The average HOMA2 were 1.4 and 75 percentile 1.9. The prevalence of metabolic syndrome was present in 23%. The association test with a p < 0.05 was considered significant for metabolic syndrome dysglucemia and obesity, but not for other components of metabolic syndrome. The triglycerides level correlated with insulin resistance (r = 0.325, p = 0.011), insulin resistance with glucose (r = 0.535, p = 0.000) and insulin resistance with BMI (r = 0.282, p = 0.28). CONCLUSIONS: It is important to properly define the components for the presence of metabolic syndrome in older women due to not all who qualify as obese have metabolic syndrome, and neither all the metabolic syndrome are associated with insulin resistance. The single alteration of one of the components of metabolic syndrome is not sufficient to cause insulin resistance.
Assuntos
Síndrome Metabólica/epidemiologia , Idade de Início , Idoso , Envelhecimento/metabolismo , Glicemia/análise , Pressão Sanguínea , Índice de Massa Corporal , Estudos de Coortes , Estudos Transversais , Feminino , Humanos , Hipertrigliceridemia/epidemiologia , Resistência à Insulina , México/epidemiologia , Pessoa de Meia-Idade , Obesidade/epidemiologia , Prevalência , Estudos Retrospectivos , Relação Cintura-QuadrilRESUMO
BACKGROUND: Chromosomal abnormalities are a frequent cause of infertility. There is not consensus if should be included in the work-up of infertile couple. OBJECTIVE: to evaluate the prevalence of chromosomal abnormalities in our population of infertile couple and support the cytogenetic exam in the initial protocol. PATIENTS AND METHODS: Retrospective study of 787 infertile patients divided in five groups, to whom a cytogenetic exam was performed between January 2004 and April 2007. RESULTS: The prevalence of general chromosomal abnormalities was 12.5% (98/787). We found a 14.8% (34/229) with severe male factor, 14.3% (2/14) with premature ovarian failure, 12.3% (20/162) with recurrent pregnancy loss, 8% (9/112) idiopathic infertility and 12.2% (33/270) associated with other causes. The major alterations correspond to trisomies, translocations, and 9 chromosome markers. CONCLUSIONS: The results of this study are consistent with those reported in the literature which are associated with a greater prevalence of chromosomal abnormalities in infertile couples compared with the general population, this findings show the importance of consider the cytogenetic study in the initial diagnosis protocol of infertile couple.