RESUMO
Yerba mate tea is a very common beverage in some countries of South America. We conducted a case-control study on an individual basis using hospital records to investigate the association between Parkinson's disease (PD) and yerba mate intake. A case was defined as an age of ≥ 40 years with ≥ 1 year of PD. Each case was individually matched by two controls. Exposure was measured by yerba mate consumption, coffee, tea, and alcohol intake and smoking status. The sample consisted of 223 PD patients (mean age 68 years and mean disease duration 7.3 years) and 406 controls. There was an inverse association between yerba mate "bombilla" consumption and PD (OR 0.64, 95% CI: 0.54-0.76, p=0.00001). A multivariate analysis with a logistic regression adjusted by sex, alcohol intake and smoking provided the following results: yerba mate (OR 0.63, 95% CI: 0.53-0.76), tea (OR 0.60, 95% CI: 0.42-0.86), coffee (OR 0.51, 95% CI: 0.35-0.73). We found an inverse association between yerba mate consumption and PD. These results led us to hypothesize that yerba mate may have a potential protective role in the development of PD.
Assuntos
Ilex paraguariensis/metabolismo , Doença de Parkinson/epidemiologia , Doença de Parkinson/prevenção & controle , Idoso , Consumo de Bebidas Alcoólicas/efeitos adversos , Análise de Variância , Argentina/epidemiologia , Estudos de Casos e Controles , Café/efeitos adversos , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Doença de Parkinson/etiologia , Reprodutibilidade dos Testes , Estudos Retrospectivos , Fatores de Risco , Fumar/efeitos adversosRESUMO
OBJECTIVE: To determine the prevalence of stroke and its distribution by age, sex and clinical type, and to use the outcomes for prevention, care and rehabilitation. DESIGN/METHOD: The survey was conducted in Junín, a town of about 75,000 inhabitants, situated in an agricultural region of the Province of Buenos Aires, Argentina. Systematic sampling was used to select 5,839 dwellings (sampling fraction approximately 25%) and 5,648 (97%) households participated in our study, including 17,049 participants. The initial stage of the study involved a case-finding strategy consisting of a two-stage screening approach in the selected households; household screening was followed by neurological examination. We used a point prevalence with reference date January 1, 1991. Stroke was defined according to the WHO criteria. RESULTS: As of January 1, 1991, 148 subjects were identified as cases of stroke (79.6% ischemic and 20.4% hemorrhagic). Point prevalence ratio was 868.1 cases per 100,000 inhabitants in the total population (473.4/100,000 age adjusted to the worldwide population) and 1,867.4 in those patients of 40 years of age or older (1,534.4/100,000 age adjusted to the worldwide population). In both sexes, prevalence increased with age. However, this increase was more significant and sustained in men of 50 years of age and older. Moderate to severe disability was observed in 52% of patients. CONCLUSION: This is one of the first community-based studies conducted in Argentina about the prevalence of stroke. Final results are similar to those reported in other developed countries.