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1.
Disabil Rehabil Assist Technol ; 18(4): 369-377, 2023 05.
Artigo em Inglês | MEDLINE | ID: mdl-33306923

RESUMO

SUMMARY: The voice is an important tool for people who use it daily in their occupations. However, what technological options are available to such individuals to allow them to monitor or take care of their voices? OBJECTIVE: The purpose of this study is to answer two research questions: (1) What technologies exist to monitor or take care of the voice in occupational voice users? (2) What is the technology readiness level (TRL) of the technologies used to monitor or take care of the voice in occupational voice users? DATA SOURCES: Embase, IEEE, Medline, Proquest, PubMed, Scopus, and Web of Science. METHODS: A systematic literature review was conducted. Articles that reported results regarding technologies (hardware, software, or mobile apps) that were used to monitor or take care of the voice in occupational voice users were included. RESULTS: After reviewing 4581 abstracts, 10 full text studies were included in the literature review. The technologies found include 30% hardware, 30% hardware plus software, and 50% mobile apps, with an overall TRL mean of 5.3 (SD = 2.3). CONCLUSION: Further research is necessary for higher validity in the studies and to increase the readiness in the development of current technologies to offer more options for this population.Implications for RehabilitationThe evidence for the impact of the use of the technologies for occupational voice users is still lowThere is emerging evidence that mobile apps and artificial intelligence algorithms can be used to investigate vocal disorders or potential risks in occupational voice usersMore research is required to increase the readiness developmental stage of current technologies for occupational voice users.


Assuntos
Aplicativos Móveis , Envio de Mensagens de Texto , Humanos , Inteligência Artificial , Algoritmos
2.
Am J Med Genet C Semin Med Genet ; 184(4): 1009-1013, 2020 12.
Artigo em Inglês | MEDLINE | ID: mdl-33300677

RESUMO

We report the case of a 17-year-old girl with Tyrosinemia type 1a who carried a planned pregnancy to term while being under 2-(2-nitro-4-trifluoromethylbenzoyl)-1,3-cyclohexanedione (NTBC, nitisinone) treatment and a tyrosine- and phenylalanine-restricted diet. She was on treatment since 2 months of age with poor metabolic control prior to her pregnancy (tyrosine 838 ± 106 umol/L). NTBC and a low tyrosine and phenylalanine diet were continued during her pregnancy. She unfortunately suffered from urinary tract infection and anemia during her pregnancy, with median plasma tyrosine and phenylalanine levels of 613 ± 106 umol/L (200-400 umol/L) and 40.2 ± 8 umol/L (35-90 umol/L), respectively. After 40 weeks of gestation, the patient gave birth to a healthy boy, with no adverse effects related to the use of NTBC. The newborn presented with a transitory elevation of plasma tyrosine levels and normal phenylalanine, methionine, and succinylacetone levels. By 12 months of age, the child was determined to have normal psychomotor development. At 20 months old, he was diagnosed with a mild developmental delay; however, global cognitive evaluation with the Wechsler Intelligence Scale for Children (WISC) test at 5 years old showed normal performance. Here, we discuss one of the few reported cases of nitisinone treatment during pregnancy and demonstrate a lack of teratogenicity and long-term cognitive disabilities.


Assuntos
Tirosinemias , Adolescente , Chile , Dieta , Feminino , Humanos , Fenilalanina , Tirosina , Tirosinemias/diagnóstico , Tirosinemias/tratamento farmacológico
3.
Cir. gen ; 33(2): 121-126, abr.-jun. 2011. ilus
Artigo em Espanhol | LILACS | ID: lil-706846

RESUMO

Objetivo: Narrar la vida y obra de John Benjamín Murphy. Diseño: Ensayo histórico (16 referencias). Sede: Departamento de Investigación, Escuela de Medicina. Resultado: John Benjamin Murphy nació en Apletton, Wisconsin el 21 de diciembre de 1857. Egresó del Rush Medical College en 1876. Tras ejercer algunos años, en 1882 decide continuar su preparación en Europa siendo discípulo de Theodore Billroth. Regresa a su país como profesor en su Alma Mater, al tiempo que comenzó sus prácticas quirúrgicas e investigación clínica ante la Chicago Medical Society. Su investigación a lo largo de esos años lo llevó, en 1895, a convertirse en Jefe de Cirujanos en el Hospital Mercy en Chicago. A lo largo de su desempeño profesional, trabajó en distintas áreas de la medicina; se le reconocen valiosas aportaciones en cirugía vascular, tuberculosis pulmonar, neurocirugía y principalmente en semiología digestiva, donde define el signo de Murphy revolucionando el tratamiento para pacientes con colecistitis. Murphy publicó sus primeros trabajos en los primeros números de lo que hoy son Clínicas Quirúrgicas de Norteamérica. En el hospital Mercy, innovó en la enseñanza de la medicina a través de sus ''wet clinics''. Sin duda, un hombre muy propositivo para su época, que marcó la diferencia en la práctica quirúrgica, respetado y a la vez muy criticado por sus colegas. Falleció el día 11 de agosto de 1916, marcando los inicios de la práctica médica moderna.


Objective: To narrate the life and work of John Benjamin Murphy. Design: Historical Assay (16 references). Setting: Research Department, School of Medicine, Universidad Cristobal Colón, Veracruz, Mexico. Result: John Benjamin Murphy was born in Apletton, WI, USA, on the 21st of December 1857. He graduated from Rush Medical College in 1876. After practicing medicine for some years, in 1882, he decided to continue his preparation in Europe and became a pupil of Theodore Billroth. He returned to his country as a professor at his Alma Mater, and at the same time he started his surgical practices and clinical research at the Chicago Medical Society. His research along these years, led him, in 1895, to become the surgeon-in-chief at the Mercy hospital in Chicago. Along his professional career he worked in different areas of medicine, and he is known for valuable work done in vascular surgery, pulmonary tuberculosis, neurosurgery, and mainly in digestive semiology, where he defined the Murphy sign, changing completely the treatment of patients with cholecystitis. Murphy published his first works in what is known today as The Surgical Clinics of Northamerica. At the Mercy hospital, he innovated the teaching of medicine through his ''wet clinics''. Without any doubt, he was a very purposeful man for his time, who made a difference in the surgical practice, he was respected and, at the same time, criticized by his colleagues. He died on August 11, 1916, hallmarking the start of modern medical practice.

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