RESUMO
The usefulness of liver scintiscann and its correlation with final diagnosis was evaluated in a retrospective study of 195 patients with suspected hepatic disease. It was found that the overall sensitivity and specificity were 83% and 61%, respectively. These data are in accordance with other previously described. The highest diagnostic accuracy was found in diffuse and focal hepatocellular disease. Multifocal disease group showed the highest false negative interpretations. The role of the factors affecting our results is discussed.
Assuntos
Hepatopatias/diagnóstico por imagem , Fígado/diagnóstico por imagem , Estudos de Avaliação como Assunto , Humanos , Hepatopatias/diagnóstico , Cintilografia , Estudos RetrospectivosRESUMO
En un estudio retrospectivo de 195 pacientes en los que se sospechaba hepatopatia se evaluo la utilidad de la centellografia hepatica en cuanto a su correlacion con el diagnostico de certeza obtenido por otros metodos. Se observo que la sensibilidad y especificidad globales, 83% y 61% respectivamente estan dentro de las cifras ya comunicadas en otras series. En cuanto a la utilidad en las diferentes hepatopatias se observo una muy buena correlacion en la enfermedad difusa y le enfermedad unifocal en tanto que la enfermedad multifocal presento el mayor numero de falsos negativos.Se comentan los factores que pudieron influir en estos resultados
Assuntos
Humanos , Fígado , Hepatopatias , CintilografiaRESUMO
The usefulness of liver scintiscann and its correlation with final diagnosis was evaluated in a retrospective study of 195 patients with suspected hepatic disease. It was found that the overall sensitivity and specificity were 83
and 61
, respectively. These data are in accordance with other previously described. The highest diagnostic accuracy was found in diffuse and focal hepatocellular disease. Multifocal disease group showed the highest false negative interpretations. The role of the factors affecting our results is discussed.
RESUMO
En un estudio retrospectivo de 195 pacientes en los que se sospechaba hepatopatia se evaluo la utilidad de la centellografia hepatica en cuanto a su correlacion con el diagnostico de certeza obtenido por otros metodos. Se observo que la sensibilidad y especificidad globales, 83% y 61% respectivamente estan dentro de las cifras ya comunicadas en otras series. En cuanto a la utilidad en las diferentes hepatopatias se observo una muy buena correlacion en la enfermedad difusa y le enfermedad unifocal en tanto que la enfermedad multifocal presento el mayor numero de falsos negativos.Se comentan los factores que pudieron influir en estos resultados
Assuntos
Humanos , Cintilografia , Fígado , HepatopatiasRESUMO
Forty eight patients were evaluated to ascertain a correlation (if any) between gastric acid secretion, fasting and post prandial serum gastrin levels, gastric biopsy (antrum and fundus) and gastric emptying time after a standard test meal. The following conclusions were obtained: a) 57.8% of patients with atrophic gastritis and achlorhydria had evaluated serum gastrin levels; b) most patients with high gastrin levels had normal antrum on biopsy or showed only minimal inflamatory changes, while those with normal gastrin levels disclosed more pronounced histological changes; c) patients with achlorhydria had slower gastric emptying rates, and this was more evident among those with higher gastrin levels (though differences were not statistically significant). Further studies are required for a better understanding of the relationship between gastric emptying rate and gastrin levels in patients with chronic gastritis.
Assuntos
Acloridria/fisiopatologia , Esvaziamento Gástrico , Gastrinas/sangue , Gastrite/fisiopatologia , Adulto , Idoso , Doença Crônica , Feminino , Suco Gástrico/metabolismo , Humanos , Índio , Masculino , Pessoa de Meia-Idade , Antro Pilórico/patologia , Antro Pilórico/fisiopatologia , RadioisótoposRESUMO
Forty eight patients were evaluated to ascertain a correlation (if any) between gastric acid secretion, fasting and post prandial serum gastrin levels, gastric biopsy (antrum and fundus) and gastric emptying time after a standard test meal. The following conclusions were obtained: a) 57.8
of patients with atrophic gastritis and achlorhydria had evaluated serum gastrin levels; b) most patients with high gastrin levels had normal antrum on biopsy or showed only minimal inflamatory changes, while those with normal gastrin levels disclosed more pronounced histological changes; c) patients with achlorhydria had slower gastric emptying rates, and this was more evident among those with higher gastrin levels (though differences were not statistically significant). Further studies are required for a better understanding of the relationship between gastric emptying rate and gastrin levels in patients with chronic gastritis.
RESUMO
Forty eight patients were evaluated to ascertain a correlation (if any) between gastric acid secretion, fasting and post prandial serum gastrin levels, gastric biopsy (antrum and fundus) and gastric emptying time after a standard test meal. The following conclusions were obtained: a) 57.8
of patients with atrophic gastritis and achlorhydria had evaluated serum gastrin levels; b) most patients with high gastrin levels had normal antrum on biopsy or showed only minimal inflamatory changes, while those with normal gastrin levels disclosed more pronounced histological changes; c) patients with achlorhydria had slower gastric emptying rates, and this was more evident among those with higher gastrin levels (though differences were not statistically significant). Further studies are required for a better understanding of the relationship between gastric emptying rate and gastrin levels in patients with chronic gastritis.