RESUMO
OBJECTIVE: this study aims to compare the profile of octogenarian individuals with colorectal cancer and those younger than 80 years of age regarding gender distribution, mean age of patients, length of hospital stay, type of surgery performed and postoperative complications. METHODS: this study was carried out at the Coloproctology Department of Hospital Felicio Rocho, Belo Horizonte, state of Minas Gerais, Brazil. We evaluated 438 patients with colorectal cancer undergoing curative surgery as disease treatment. Data was collected using specific guidelines established by the health care team during a clinical meeting. This is a descriptive and retrospective study that compared the profile of 52 octogenarian patients (Group I) and 386 patients younger than 80 years (Group II). RESULTS: the female gender predominated in group I with 69%, whereas the distribution between genders was similar in group II, with 50.3% of women. Mean age in group I was 84.5 years. The mean hospital stay was 8.25 days for patients younger than 80 years and 9.3 for the octogenarians. Group I had a complication rate of 28.84%, while in Group II it was 22.02%. CONCLUSION: age older than 80 years does not contraindicate colorectal surgery. (AU)
OBJETIVO: este trabalho pretende comparar o perfil de pessoas octagenárias portadoras de CaCR com aquelas com idade inferior a 80 anos, no que diz respeito à distribuição por sexo, idade média dos pacientes, tempo de internação hospitalar, tipo de cirurgia realizada, complicações pós-operatórias. MÉTODOS: este trabalho foi desenvolvido pelo Serviço de Coloproctologia do Hospital Felício Rocho, Belo Horizonte - MG, Brasil. Foram avaliados 438 pacientes portadores de Câncer Colorretal submetidos a procedimento cirúrgico como medida curativa para a doença. Os dados foram coletados através de protocolo específico criado pela equipe em reunião clínica. Trata-se de um estudo descritivo e retrospectivo que comparou o perfil de 52 pacientes octagenários (Grupo I), com 386 de idade inferior a 80 anos (Grupo II). RESULTADOS: o sexo feminino predomina com 69% no grupo I, já no grupo II a distribuição foi semelhante, com 50, 3% de mulheres. A idade média do grupo I foi de 84,5. O tempo médio de internação foi de 8,25 dias para pacientes mais jovens e de 9,3 para os octagenários. O grupo I apresentou taxa de complicações de 28,84%, enquanto o Grupo II de 22,02%. CONCLUSÃO: idade superior a 80 anos não contraindica cirurgia colorretal. (AU)
Assuntos
Humanos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Idoso , Idoso de 80 Anos ou mais , Procedimentos Cirúrgicos do Sistema Digestório , Neoplasias Colorretais/cirurgia , Complicações Pós-Operatórias , Idoso de 80 Anos ou maisRESUMO
This study investigated the acute hormonal response to three different rest periods between sets of a traditional lower body resistance training session in young women. Twelve healthy trained females (26.83+/-3.93 years) participated in the study. On three separate sessions of a lower body resistance exercise protocol, subjects were assigned in a random order a rest interval of 30s (P30), 60s (P60) or 120s (P120) between sets. The resistance exercise session consisted of four lower body exercises with three sets performed until contractile failure using 10-repetition maximum (RM) load. Blood samples were drawn for determination of serum growth hormone (GH) and cortisol concentrations before exercise (T0), immediately after each training session (T1), and after 5min (T5), 15min (T15), and 30min (T30) of recovery. Statistical evaluation of the area under the time-concentration relationship for GH (GHauc) and for cortisol (Cauc) were analyzed using a one-way ANOVA There were no differences among protocols (P30, P60 and P120) in the serum GH and cortisol concentrations at baseline (T0). However, as compared to T0, all protocols led to acute increases (p<0.05) in serum GH concentrations after each training session. The GHauc was greater for P30 than for both P60 and P120, however, there were no differences between P60 and P120. The Cauc were not different among protocols. Thus, the magnitude of acute GH responses in previously strength-trained women appears greater with a 30-s rest interval between sets compared to longer rest periods of 60- or 120-s.
Assuntos
Hormônio do Crescimento Humano/sangue , Hidrocortisona/sangue , Extremidade Inferior/fisiologia , Treinamento Resistido/métodos , Descanso/fisiologia , Adulto , Análise de Variância , Feminino , Hormônios/sangue , Humanos , Contração Isométrica/fisiologia , Fatores de Tempo , Adulto JovemRESUMO
O objetivo deste estudo foi examinar as respostas agudas de três diferentes intervalos de recuperação entre séries, durante uma sessão tradicional de exercícios resistidos para membros inferiores em mulheres jovens. Participaram deste estudo doze mulheres aparentemente saudáveis e treinadas em exercícios resistidos (26,83 ± 3,93 anos). Em três momentos distintos, os sujeitos realizaram em ordem contra balanceada, o protocolo de exercícios resistidos para membros inferiores com 30 (P30), 60 (P60) ou 120 (P120) segundos de intervalo de recuperação entre séries. A sessão de exercícios resistidos consistia de quatro exercícios para os membros inferiores (cadeira extensora, agachamento, mesa flexora e leg press), com 3 séries de 10 repetições e carga de 10 repetições máximas (RM). Coletas sangüíneas foram realizadas para determinar as concentrações do hormônio do crescimento (GH) antes do exercício (T0), imediatamente após cada sessão de exercício (T1), e 5 (T5), 15 (T15) e 30 (T30) minutos de recuperação. A avaliação estatística dos dados foi por meio da análise de variância de medidas repetidas 3 X 5 [intervalo de recuperação (30s, 60s, 120s) X tempo (T0, T1, T5, T15, T30)], com o teste post-hoc Least Significant Difference (LSD). O nível de significância estatístico utilizado foi p < 0,05 em todas as comparações. Não houve diferenças entre os protocolos (P30, P60 e P120) nas concentrações sanguíneas do GH em repouso. Porém, em relação a T0, todos os protocolos obtiveram aumentos significativos (p < 0,05) nas concentrações do GH após a sessão de exercícios. As concentrações do GH entre os protocolos foram significativamente maiores para o P30 (24,34 ng/ml) e P60 (23,07 ng/ml) quando comparadas ao P120 (17,13 ng/ml) em T1. A concentração do GH no P30 foi significativamente maior em T5, T15 e T30, quando comparada ao P60 e ao P120. A magnitude das respostas hormonais (GH) agudas em mulheres treinadas parece ser maior com 30s de intervalo entre...
PURPOSE: The purpose of this study was to examine the acute hormonal responses of three different rest periods between sets of a traditional lower body resistance training session in young women. METHODS: Twelve apparently healthy, trained females (26.83± 3.93 yrs) participated in the study protocol. On three separate sessions of a lower body resistance exercise protocol, subjects were randomly assigned a rest interval of either 30 (P30), 60 (P60) or 120 (P120) seconds between sets. The resistance exercise session consisted of four lower body exercises (bilateral knee extension, bilateral knee flexion, leg press, and squat) with 3 sets of 10 repetitions at 10-repetition maximum (RM) load. Blood samples were drawn for determination of serum growth hormone (GH) concentrations before exercise (T0), immediately after each training session (T1), and 5 (T5), 15 (T15), and 30 (T30) minutes of recovery. Statistical evaluation of the data was measured using a 3 x 5 repeated measurements analysis of variance [rest interval (30, 60, and 120 s) x time (T0, T1, T5, T15, T30)] with a least-significant difference (LSD) post-hoc procedure for all hormonal measurements. The probability level of statistical significance was set at p < 0.05 in all comparisons. RESULTS: There were no differences among protocols (P30, P60 and P120) in the serum GH concentrations at baseline (T0). However, as compared to T0, all protocols led to acute increases (p < 0.05) in serum GH concentrations after each training session. The GH concentrations between protocols were significantly higher for P30 (24.34 ng/ml) and P60 (23.07 ng/ml) as compared to P120 (17.13 ng/ml) at T1. The P30 GH concentrations were significantly higher at T5, T15, and T30 as compared to P60 and P120. CONCLUSION: The magnitude of acute hormonal (GH) responses in previously strength-trained women seems to be greater with a 30-second rest interval between sets compared to longer rest periods (60s or 120s).
Assuntos
Humanos , Feminino , Adulto Jovem , Descanso/fisiologia , Exercício Físico/fisiologia , Hormônio do Crescimento/análise , Treinamento Resistido , MulheresRESUMO
OBJECTIVE: To evaluate plasma levels of angiogenic factors and their association with preeclampsia. METHODS: Twenty-three women with preeclampsia and nine normotensive pregnant women from the Maternity of Hospital das Clínicas of Belo Horizonte/MG-Brazil were assessed by National High Blood Pressure Education Program Working Group Creteria (NHBPEPWG). The plasma levels of vascular endothelial growth factor (VEGF) and Placental growth factor (PlGF) were determined by ELISA assay. RESULTS: Plasma concentration of PlGF was 12-fold lower in preeclampsia versus non preeclampsia pregnancies. An inverse correlation was observed between PlGF plasma levels and mean arterial pressure (MAP); a decrease in 1pg/mL of PlGF resulted in 6.18 mm Hg increase in MAP. CONCLUSION: These results indicate that PlGF is related to MAP in pregnant women.