RESUMO
Two cases of pulmonary coccidioidomycosis are reported; both patients were treated with surgery because the pulmonary lesion did not respond to medical treatment, both live in endemic areas of coccidioidomycosis. Both patients had pulmonary cavities; one of them with secondary empyema, in the other the cavity enlarged progressivelly and the patient presented hemoptysis. The two patients were treated with ketoconazole before the surgery, neither of them responded to medical treatment. The empyema was treated with a pleural tube but the problem was not resolved; the surgical treatment was decided and a superior right anterior segmentectomy was performed in one patient and a superior left lobectomy plus decortication in the ohter. Both patients were treated with ketoconazole after the surgery, and actually there is not evidence of active infection.